The control of puncturevine in southern peas with imazethapyr and imazaquin and the potential for carryover of these herbicides to spinach was evaluated in Arkansas. Imazethapyr (0.07 kg ai ha−1) and imazaquin (0.14 kg ha−1) applied to southern peas either PPI tank-mixed with trifluralin (0.84 kg ha−1) or PRE or POST following trifluralin controlled puncturevine at least 70%. Imazaquin and imazethapyr remaining in soil after use caused injury and yield reduction to spinach planted 3 to 4 mo after herbicide application in the fall after southern pea harvest. In spring spinach planted 8 to 9 mo after herbicide application, the only injury observed was from soil residues of imazethapyr applied POST in one of two years, with no yield reduction. In rate by timing experiments, imazethapyr at 0.07 kg ha−1 applied PPI, PRE, and 3 and 6 d after puncturevine emergence controlled puncturevine at least 95% at the 2-wk rating. At the 4-wk rating, imazethapyr at 0.07 kg ha−1 applied PRE provided this level of control. Imazaquin at 0.07 and 0.14 kg ha−1 controlled puncturevine greater than 93% when applied up to 12 d after emergence. Puncturevine control was less with both herbicides at lower rates and as application timing increased.