Field studies were conducted from 1982 to 1984 to evaluate the effectiveness of SC-0224 (trimethylsulfonium carboxymethylaminomethylphosphonate) and glyphosate [N-(phosphonomethyl)glycine] for quackgrass [Agropyron repens (L.) Beauv. # AGRRE] control. The herbicides were compared 1) in different rates and carrier volumes, 2) on several spring and fall application dates, and 3) with varying time intervals between application and moldboard plowing. Glyphosate and SC-0224 controlled quackgrass equally well at carrier volumes of 25 to 400 L/ha. Both herbicides generally provided similar control as fall and spring applications and with time intervals of 12 to 96 h between application and plowing. Occasionally the low rate of SC-0024 gave less quackgrass control the next season than the same rate of glyphosate. Adding nonionic surfactant at 0.5% (v/v) did not influence the phytotoxicity of these herbicides at the rates and carrier volumes tested. These herbicides controlled quackgrass comparably and greater than 85% when applied under appropriate environmental conditions.