The present study examines the directionality of links between romantic relationship conflict and psychological distress in premarital relationships of emerging adults. A total of 182 participants (Mage = 21.23; SDage = 1.62; 85.16% female) provided data at both Time 1 (T1) and Time 2 (T2). Participants responded to a battery of questions related to romantic relationship conflict and psychological distress. The data for the present study were collected at two time points during spring semester of 2018: First week (Time 1) and the last week of the semester, Week 14 (Time 2). A two-wave two variable cross-lagged autoregressive panel model was conducted to examine the links between relationship conflict and psychological distress over time in emerging adults. Using a latent cross-lagged panel model, we found that romantic relationship conflict at T1 significantly predicted psychological distress at T2, but psychological distress at T1 was not associated with subsequent romantic relationship conflict at T2, after controlling for autoregressive effects. The results highlighted the key role of romantic relationship conflict in predicting later psychological distress. Limitations and implications are discussed and future directions are suggested.