Field experiments were conducted in 1988 and 1989 to evaluate imazethapyr for weed control in peanuts. Imazethapyr was applied PRE or POST at 3, 5, or 7 weeks after crop emergence (WAE) at 0.071 kg ai ha–1. Imazethapyr applied PRE controlled common lambsquarters 85%, prickly sida 92%, and a mixture of entireleaf, ivyleaf, pitted, and tall morningglory species 77%. Morningglory control was at least 91% with imazethapyr plus metolachlor PRE followed by imazethapyr plus 2,4–DB or imazethapyr plus acifluorfen at 3, 5, or 7 WAE. Yields from systems that included metolachlor plus imazethapyr PRE followed by imazethapyr plus acifluorfen, imazethapyr plus 2,4–DB, or acifluorfen plus 2,4–DB at 3 WAE were greater than yields from the handweeded check. All systems with imazethapyr plus metolachlor PRE followed by any POST treatment except imazethapyr plus acifluorfen 7 WAE provided net returns equivalent to the herbicide standard of metolachlor PRE and acifluorfen and bentazon plus 2,4–DB 3 WAE. All systems except imazethapyr PRE provided greater net returns than the handweeded weed–free check.