Let $p$ be a prime number, $k$ a finite field of characteristic $p>0$ and $K/k$ a finitely generated extension of fields. Let $A$ be a $K$-abelian variety such that all the isogeny factors are neither isotrivial nor of $p$-rank zero. We give a necessary and sufficient condition for the finite generation of $A(K^{\mathrm {perf}})$ in terms of the action of $\mathrm {End}(A)\otimes \mathbb {Q}_p$ on the $p$-divisible group $A[p^{\infty }]$ of $A$. In particular, we prove that if $\mathrm {End}(A)\otimes \mathbb {Q}_p$ is a division algebra, then $A(K^{\mathrm {perf}})$ is finitely generated. This implies the ‘full’ Mordell–Lang conjecture for these abelian varieties. In addition, we prove that all the infinitely $p$-divisible elements in $A(K^{\mathrm {perf}})$ are torsion. These reprove and extend previous results to the non-ordinary case.

In the framework of Berthelot’s theory of arithmetic ${\mathcal{D}}$-modules, we prove the $p$-adic analogue of Betti number estimates and we give some standard applications.

Let 𝒱 be a mixed characteristic complete discrete valuation ring with perfect residue field k. We solve Berthelot’s conjectures on the stability of the holonomicity over smooth projective formal 𝒱-schemes. Then we build a category of F-complexes of arithmetic 𝒟-modules over quasi-projective k-varieties with bounded and holonomic cohomology. We obtain its stability under Grothendieck’s six operations.