Oocyte cryopreservation represents an attractive and the least invasive option of fertility preservation strategy for patients wishing to retain their choice of a male partner. Recent advances in vitrification techniques have markedly improved the efficacy of oocyte cryopreservation, demonstrating that vitrification may be more effective than the conventional slow-cooling method. The proposed mechanism of vitrification uses a high concentration of cryoprotectant (CPA) and extremely rapid cooling and warming rates in order to avoid intra-and extracellular ice formation. The commonly used CPAs for cryopreservation of oocytes and embryos are small neutral solutes such as ethylene glycol (EG), 1,2-propanediol (PROH), dimethyl sulfoxide (DMSO), and glycerol. Some devices used for vitrification include the McGill cryoleaf, cryotip, cryotop, nylon loop or cryoloop, thin capillary or open pulled straws, hemi-straws, and electron microscope copper/gold grids. The oocyte vitrification technique offers a realistic hope of fertility preservation for women without partners.