Experiments were conducted over 4 yr to investigate the effects of four postemergence herbicides on soybean [Glycine max (L.) Merr. ‘Williams 79’] yield under weed-free conditions. Bentazon [3-(1-methylethyl)-(1H)-2,1,3-benzothiadiazin-4(3H)-one 2,2-dioxide], acifluorfen {5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoic acid}, and naptalam/dinoseb {2-[(1-naphthalenylamino)carbonyl] benzoic acid}/[2-(1-methylpropyl)-4,6-dinitrophenol] alone and in combination with 2,4-DB [4-(2,4-dichlorophenoxy) butyric acid] applied to soybeans at the V3 and V5 soybean growth stages caused early crop injury, but soybeans outgrew most of the injury by 21 days and there was no effect on yield. Bentazon plus 2,4-DB with or without adjuvant did not affect the yield of five soybean cultivars tested.