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Candidate models for how neurons or networks operate must be validated against experimental data. For this, it is necessary to have a good model for the measurement itself. For example, to compare model predictions from cortical networks with electrical signals recorded by electrodes placed on the cortical surface or the head scalp, the so-called volume conductor theory is required to make a proper quantitative link between the network activity and the measured signals. Here we describe the physics and modelling of electric, magnetic and other measurements of brain activity. The physical principles behind electric and magnetic stimulation of brain tissue are the same as those covering electric and magnetic measurements, and are also outlined.
This chapter describes pseudoscience and questionable ideas related to obsessive-compulsive disorder and other related disorders. The chapter opens by discussing controversies such as the assumptions of pseudoscientific medical interventions. Dubious treatments include energy therapies, neurofeedback, thought stopping, psychodynamic therapy, ketamine, magnetic stimulation, and new age wellness remedies. The chapter closes by reviewing research-supported approaches.
The purpose of this study was investigating the effectiveness of rTMS (repetitive transcranial of magnetic stimulation) on increase social performance in patients with recurrent major depression.
Method
It was used a quasi-experimental, pretest–posttest design with control group, a sample consisting of 32 patients who had depression on the basis of DSM-IV diagnostic criteria, SCID and BDI-II scales and were randomly assigned to two groups.
The experimental group underwent 20 sessions of rTMS as the independent factor and both groups (control & experimental) had 12-session psychotherapy and drugs treatment. Upon the intervention, both groups were tested with two tests (BDI-II & SASS). To determine the effect of the independent factor on the dependent factor of rTMS.
Data were analyzed by t-test.
Results
The comparison between pre- & posttest of all the tests showed the reduction of signs & symptoms of depression, (a = 0/05) (Beck scale P ≤ 0/001 & F = 30) and increase social performance in participants (P ≤ 0/001 & F = 83).
Conclusion
The rTMS is effect in the reduction of signs & symptoms of depression and increase social functioning in recurrent major depression.
Disclosure of interest
The authors have not supplied their declaration of competing interest.
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