Amid growing interest in studying China and India together, this special issue, “Methods in China-India Studies,” seeks to open a conversation on the relevance, approaches, and stakes of China-India research. Why should we pair China and India together, how can we best do so, and to what ends? In this introduction to the issue, the editors first discuss the rationales commonly evoked as justification for studying China and India together. The first section articulates shared intellectual commitments as lending a coherence to China-India studies, and as providing a common ground and point of departure for scholars across disciplinary boundaries. The second section outlines a history of the China-India pairing from the first century CE to the end of the twentieth century, with a focus on how a range of historical actors paired China and India under shifting political circumstances and with differing objectives. This section also offers an assessment of the methodological approaches recent scholarship has extended to studying each of these periods. As a whole, this introduction reflects on the unique challenges and opportunities of conducting China-India research, and outlines some of the contributions the China and India conceptual pairing can make to other fields of study.