Agriculture is one of the high input energy using sectors which ultimately produces the output energy for the survival of human beings. Wheat is an important cereal in the agriculture production system. It is a major food crop and staple food for many countries in the world. Higher population growth has increased demand for wheat, and this demand has been met through the adoption of modern agricultural practices which are heavily dependent on energy. The current study was planned to examine the input energy use efficiency of rainfed wheat growers in Pakistan and Turkey (countries among the top 10 global wheat producers). A total of 119 wheat growers from the rainfed areas of both countries were randomly selected. The data envelopment analysis was executed to estimate the input energy use efficiency score of the growers. The results of the study revealed that almost a similar source of input energy is used in both countries in wheat cultivation. The largest input energy consumption in Turkey was nitrogen fertilizer (10,531.50 MJ ha−1), while in Pakistan was farmyard manure (12,837.32 MJ ha−1). The Turkish growers have higher energy use efficiency 2.42 as compared to Pakistani growers, whose energy use efficiency was 1.09. Results further revealed that there is a substantial potential for energy savings in both countries by optimizing energy use. The study concluded that the exchange of energy-efficient practices between both countries can significantly reduce energy use and improve the yield of wheat.