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1 results

  • A large A(H3N2) influenza outbreak with a high attack rate in a drug user community in Italy, April 2022

  • Maria Gori, Clara Fappani, Silvia Bianchi, Marta Canuti, Daniela Colzani, Paolo Ottogalli, Sarah Duehren, Elisabetta Tanzi, Antonella Amendola, Antonio Boschini
  • Journal:
    Epidemiology & Infection / Volume 151 / 2023
    Published online by Cambridge University Press:
    19 January 2023, e36
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  • Despite the COVID-19 pandemic, influenza remains an important issue. Especially in community settings, influenza outbreaks can be difficult to control and can result in high attack rates. In April 2022, a large A(H3N2) influenza outbreak spread in the largest Italian drug-rehabilitation community. One hundred eighty-four individuals presented influenza-like symptoms (attack rate of 26.2%); 56% previously received the influenza vaccine. Sequence analyses highlighted a genetic drift from the vaccine strain, which may have caused the observed lack of protection.