This paper is an attempt to understand how people, in the daily practice of interacting with material culture, created, dealt with and interpreted complex and socially stressful historical processes. A 16th-century timber-framed burgher house, the Reformation and industrialization are the focus of attention. Today the house stands in a museum of cultural history in the south Scandinavian town of Lund, but it once was built in the nearby city of Malmö. Through studies of architecture and spatial analysis, as well as studies of alterations to the house and its surroundings, the biography of the house is followed back to its physical and mental origins. The architecture as well as changes in its appearance can be understood by the use of space as well as the concept of topophilia. The paper ends by relating results to contemporary sociological theories. It is argued that humans structure society through material culture, history (remembrance) and space.