Digital radar waveforms such as orthogonal frequency-division multiplexing (OFDM) often have the disadvantage that they require high sampling rates if fine range resolutions have to be achieved. The frequency comb OFDM radar scheme offers a possibility to overcome this drawback and to improve the range resolution without increasing the sampling rate. Simultaneously, the high unambiguous velocity, which is one of the advantages of digital radar waveforms, is retained and due to the simple generation of orthogonal transmit signals, it is well suited for multiple-input multiple-output (MIMO) applications. To prove all these features of the frequency comb OFDM radar scheme, a suitable 4 × 4 MIMO demonstrator including frequency comb generation as well as up- and downconversion with these combs has been set up. Its functionality has been validated with real measurements in an anechoic chamber in conjunction with a radar target simulator to emulate very high velocities.