Three sites of Kharga Oasis (Dush, Labakha, and El-Deir), which were explored between 1981 and 2010, are considered in this chapter. They were occupied from the end of the fourth century BC till the early fifth century AD. About a thousand buried individuals were examined. The studies concerned sex ratio, age at death, causes of death, and pathology of mummies. More men than women were discovered, and the number of children found was particularly high in the Christian cemetery at El-Deir. Regarding age at death, the main feature is the proportion of women between 12 and 40 (as at many cemeteries). The pathological study, mainly based on X-rays, revealed problems with bones (fractures, arthritis, scoliosis…), problems with teeth (worn teeth, decay cases), and many cases of bilharzia. Presence of GAL (growth arrest lines) was observed on many mummies or skeletons,indicating periods when food was inadequate. Exploring cemeteries revealed the activities of their inhabitants: they were mainly farmers and craftsmen involved in potting, weaving, wickerwork, stone-cutting, and woodwork. There were obviously “rich” and “poor” tombs, but differences in quality could be due to an impoverishment of populations between Ptolemaic and Roman times.