Field experiments were conducted in southwestern Oklahoma near Colony in 2000 and near Ft. Cobb in 2001 to quantify the effect of time of removal of a natural population of crownbeard on peanut yield. Weed densities and dry weed weights were measured at eight weed-removal times, and in-shell peanut yields were determined at harvest. Crownbeard was removed at 0 (the weed-free check), 4, 6, 8, 10, 12, 14, and 16 wk (full season) after crop emergence (WAE). Weed density was a poor predictor for dry weed weight and peanut yield; however, dry weed weight and time of removal were good predictors for peanut yield. Weed growth was minimal up to 4 WAE and increased linearly after that time. For each week of weed growth, a 0.52 kg/plot increase in dry weed weight was measured. Peanut yield decreased linearly because of crownbeard competition. For each kilogram per plot increase in dry weed weight, a 129 kg/ha or 5.1% peanut yield reduction took place. For each week of weed interference, a 75 kg/ha or 2.8% peanut yield reduction occurred. Crownbeard removal by or before 4 WAE will minimize losses in peanut yield because of interference.