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The workup of urolithiasis during pregnancy often requires a multidisciplinary approach. This case examines the physical and anatomical changes in pregnancy that can lead to urolithiasis and the pathophysiology of the disease. Through a patient case, the physical findings, laboratory tests, and imaging studies needed to establish a diagnosis of urolithiasis in pregnancy is reviewed. Treatment options for urolithiasis and special considerations in the pregnant population are then discussed in detail, covering both conservative management and invasive procedures. Specific guidance is provided as to when additional imaging tests or consultation with interventional radiology or urology is warranted.
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