Since other evidence strongly suggests that the omission of Matt 16:2b–3 is the result of multiple emergence, this variant unit serves as a helpful case study to evaluate the usefulness of pre-genealogical coherence for detecting multiple emergence of a reading, an important premise of the Coherence-Based Genealogical Method (CBGM). This article adapts the Wasserman–Gurry method of assessing pre-genealogical coherence in the Synoptic Gospels (for which full collation of the relevant witnesses is presently lacking) in several ways to approximate more closely the approach used in the CBGM. It also attempts to refine the data generated by the Parallel Pericopes: Manuscript Clusters tool of the INTF at certain points. The study confirms that the assessment of pre-genealogical coherence is useful in detecting multiple emergence, coincidental agreement and contamination even based on the limited data in the Parallel Pericopes volume of the Editio Critica Maior.