In this paper, we introduce a new class of set-valued risk measures which satisfies cash sub-additivity. Dual representation for them is provided. Moreover, we also investigate dynamic set-valued cash sub-additive risk measures and discuss the corresponding multi-portfolio time consistency. The equivalent characterization of the multi-portfolio time consistency is given. Finally, an example is also given to illustrate the introduction of set-valued cash sub-additive risk measures. The present paper can be considered as a set-valued extension of scalar cash sub-additive risk measures introduced by El Karouii and Ravanelli [8].