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Over one third of the population develops cancer during their life-time and stroke associated with malignancy accounts for 10% of all hospitalized patients. With and improved survival and better life quality of patients with cancer, cancer related stroke is likely to increase. It is crucial to early diagnose an underlying malignancy to optimize treatment. It is known that a major mechanism is cancer -associated hypercoagulability and over 50% of these strokes are cryptogenic. Cancer related stroke has a high risk of recurrence an improved algorithm of diagnostic-work up and a better evidence regarding secondary prevention are needed
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