Spring-applied herbicides were evaluated in field studies conducted in 1985 through 1987 in western Nebraska for selective weed control in irrigated established alfalfa. Imazethapyr, norflurazon, pendimethalin, and prodiamine did not injure alfalfa but varied in their weed control spectrums. Overall weed densities were lowest in plots treated with norflurazon at 2.8 kg ai/ha and diuron at 1.8 kg/ha.