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2 results

  • Cross-over study of topical anaesthesia with tetracaine solution for transoral rigid laryngoscopy

  • Z-H Zhu, J Zheng, L-Y Ying, B-W Zhu, J Qian, Z-X Ma
  • Journal:
    The Journal of Laryngology & Otology / Volume 126 / Issue 11 / November 2012
    Published online by Cambridge University Press:
    11 September 2012, pp. 1150-1154
    Print publication:
    November 2012
  • Background:

    Transoral rigid laryngoscopy with videostroboscopy is the most practical method to visualise the vocal folds. The optimal topical anaesthesia regimen for transoral rigid laryngoscopy has not yet been established.

    Objective:

    To compare patient comfort and compliance with various topical anaesthetics for transoral rigid laryngoscopy.

    Methods:

    Each of 10 patients received a random topical administration of either 2 per cent lidocaine gel, 1 per cent tetracaine gel or 1 per cent tetracaine solution, 10 minutes before undergoing rigid laryngoscopy with videostroboscopy. During follow-up laryngoscopies, the agent with the lowest mean visual analogue scale score for discomfort was then used to study the timing of topical anaesthetic application: the agent was given to the patient 5, 10 or 15 minutes before laryngoscopy (with the timing randomly selected).

    Results:

    Compared with lidocaine gel or tetracaine gel, laryngoscopy with topical tetracaine solution was more comfortable. There was a statistically significant difference in discomfort score between the 5 and 10 minute application groups, but not between the 10 and 15 minute groups.

    Conclusion:

    Tetracaine solution, applied topically 10 minutes before transoral rigid laryngoscopy, significantly decreases patient discomfort.

  • Cocaine versus tetracaine in septoplasty: a prospective, randomized, controlled trial

  • E I Drivas, J K Hajiioannou, V A Lachanas, A J Bizaki, D E Kyrmizakis, J G Bizakis
  • Journal:
    The Journal of Laryngology & Otology / Volume 121 / Issue 2 / February 2007
    Published online by Cambridge University Press:
    15 August 2006, pp. 130-133
    Print publication:
    February 2007

  • Background: Successful local anaesthesia is of critical importance for the success of septoplasty, and many surgeons prefer to use cocaine for this purpose. The aim of this study was to evaluate the efficacy of cocaine 4 per cent solution, compared with tetracaine 2 per cent plus adrenaline, as a local anaesthetic for patients undergoing septoplasty.

    Methods: From December 2002 to February 2005, a prospective, randomized, controlled trial was conducted. One hundred and eight patients underwent septoplasty under local anaesthesia. Patients were randomly classified into group A and group B, in which was used respectively cocaine 4 per cent solution and tetracaine 2 per cent solution plus adrenaline. A visual analogue scale was used to evaluate the severity of patients' pain during their procedure.

    Results: Group B (tetracaine; mean rank=43.77) reported significantly less pain (p<0.001) compared with group A (cocaine; mean rank=65.23).

    Conclusions: On the basis of these findings, we recommend tetracaine as the first choice anaesthetic for nasal septoplasty; the use of cocaine should be limited.