This essay responds to Brack et al., ‘Plague and the Mongol Conquest of Baghdad (1258)? A reevaluation of the sources’, which is a critique of our 2021 essay in this journal, ‘Plague and the Fall of Baghdad (1258)’. We argue that Brack and colleagues have misunderstood our investigation as an attempt to pinpoint the exact timing of the outbreak of plague connected with the Mongol siege of Baghdad, and so believe that an altered timeframe invalidates our suggestion that plague was involved. Taking this opportunity to revisit the state of plague historiography in western Asia, we address four issues: (1) why Mongol historiography has, until recently, avoided the question of plague’s late mediaeval resurgence within the Mongol Empire and why the ‘new genetics’ of plague now makes the question unavoidable; (2) why reconstruction of the biological processes of ‘focalisation’ is now the most urgent question in plague historiography since it constitutes what we call the prodromal stage of the Black Death pandemic; (3) how a newly informed biological perspective on disease history can allow a more sensitive reading of past observers’ reports of epidemics; and finally, (4) what a plausible scenario might look like for plague’s presence in western Asia and the eastern Mediterranean region in the late-thirteenth and early-fourteenth centuries as an emerging zoonotic disease with occasional epizootic and human outbreaks, before the more catastrophic outbreaks of the 1340s commonly referred to as ‘the Black Death’.

Archaeologists in the Canary Islands have gathered substantial quantitative data from radiocarbon measurements and aDNA analyses. While undeniably helpful and necessary for apprehending past human activity, their interpretation, based on theories underpinning models developed for island chains, has lagged, leaving a gap in our understanding of processes of occupation and social network systems. The decontextualized nature of the archaeological landscape of the Canaries and a lack of consensus about proper radiocarbon methodologies are some of the factors contributing to heated scholarly debate. Here, for the Canary Islands, the author reviews the current literature on aDNA and discusses settlement theories, the chronological evidence used for occupation models, and how such perspectives align with current thinking on island colonization.

While some species of parasites can be identified to species level from archaeological remains using microscopy (i.e. Enterobius vermicularis, Clonorchis sinensis), others can only be identified to family or genus level as different species produce eggs with similar morphology (i.e. Tænia sp. and Echinococcus sp.). Molecular and immunological approaches offer the possibility to provide more precise determination at the species level. They can also identify taxa when classic parasite markers such as eggs or cysts have been destroyed over time. However, biomolecules can be poorly preserved and modern reference DNA is available only for a limited number of species of parasites, leading to the conclusion that classic microscopic observation should be combined with molecular analyses. Here we present a review of the molecular approaches used over the past two decades to identify human pathogenic helminths (Ascaris sp., Trichuris sp., E. vermicularis, Fasciola sp. etc.) or protists (Giardia sp., Trypanosoma sp., Leishmania sp. etc.). We also discuss the prospects for studying the evolution of parasites with genetics and genomics.