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Summary

Guillain Barré syndrome (GBS) is an acquired neuromuscular disorder that presents as rapidly progressive weakness and numbness, usually in an ascending fashion. The underlying pathophysiology is monophasic inflammatory immune-mediated demyelinating polyneuropathy that in many cases is triggered by viral illnesses, usually a few weeks prior to the onset of syndrome. The majority of cases are in young adults, although it can occur in pediatric and elderly age groups. GBS should be considered in the differential diagnosis of new-onset rapidly progressing weakness in an otherwise healthy individual.

The role of Campylobacter jejuni as the triggering agent of Guillain–Barré syndrome (GBS) has not been reassessed since the end of the 1990s in France. We report that the number of C. jejuni-related GBS cases increased continuously between 1996 and 2007 in the Paris region (mean annual increment: 7%, P = 0·007).

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Chapter 20 - Peripheral Nerve and Neuromuscular Disorders

Summary

Increased incidence of Campylobacter jejuni-associated Guillain–Barré syndromes in the Greater Paris area

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Chapter 20 - Peripheral Nerve and Neuromuscular Disorders

Summary

Increased incidence of Campylobacter jejuni-associated Guillain–Barré syndromes in the Greater Paris area