Archaeologists have relied on the presence of European material on Indigenous New England sites as the main indicator that a site was occupied during the sixteenth or early seventeenth centuries—a span often characterized as the Contact period. The AD 1480–1630 span is particularly difficult to sequence because it lies on a radiocarbon calibration plateau. Here we report on a program of AMS dating from an Indigenous site on Great Island on Cape Cod in Massachusetts that highlights evidence of widespread activity during the sixteenth and early seventeenth centuries—absent European material culture. Furthermore, the archaeological evidence indicates that a previously excavated colonial tavern in the same area on Great Island was the last in a long-term occupation in which “European contact” was not a defining event. Instead, the evidence points to a continuous Indigenous presence extending from the Middle Woodland period. Later colonial period activities, including those associated with European material, were mapped onto a long-standing Indigenous task-scape.