The aim of the present study, based on literature data, is to find signatures of the giant radio continuum structure Loop III on the nearby interstellar medium, and search for molecular cloud and star formation, possibly triggered by its expansion. The preliminary results are as follows: (1) The 3D map of the Local Bubble, published by Lallement et al. (2003) suggests that Loop III is probably more distant than the early models had indicated. (2) The molecular clouds at high galactic latitudes in the 2nd Galactic quadrant are probably associated with the neutral/molecular wall of Loop III. (3) Star formation in Lynds 1333 and Lynds 1082 (GF 9) might have been triggered by the expansion of Loop III. (4) The supernova(e), whose explosion produced Loop III, might have been located in the SU Cas association.