This study employs neutron activation analysis (NAA) to examine pottery from Middle Bronze Age (MBA) (c. 2200–1700 bc) Mitrou in East Lokris, central Greece. The analysis of 112 samples from all ceramic phases reveals complex patterns of production and exchange at multiple scales. Limited production of tablewares is evident within the immediate coastscape, contrasting sharply with abundant imports of tableware from other communities (most prominently, central Euboea and Boeotia), revealing a highly interconnected central Greek world. The NAA results also reinforce previous petrographic analysis, emphasizing connections with the broader regional maritime sphere, including the Cyclades, Aegina, Crete, and the south-eastern Aegean. The results challenge previous perceptions of the central Greek MBA as isolated, provide new insights into MBA connectivity, and highlight the need for further analytical work at other central Greek sites.