In this presidential address I offer a critical examination of how Africa was misrepresented in the Global North’s imaginations and media reporting during the COVID-19 pandemic. Such biased imaginings of Africa as a site of inevitable catastrophe account for the racialized under-accounting of the history of African scientists’ pioneering success in biomedical research and with epidemics. The global archives of COVID-19 pandemics must acknowledge these scientists, as well as the humanistic contributions of African artists who collaborated with health experts and produced poetic/musical performances in local and world languages to tackle biomedical and social pandemics.