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Psychiatry and Psychobiology (1)

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Baseline ACTH values and its relation to pre- and post- dexamethasone cortisol levels in depressed patients
J.A. Cabranes, I. Almoguera, J.L. Ayuso, E. Garcia-Camba, J. del Olmo
Journal:

Psychiatry and Psychobiology / Volume 2 / Issue 1 / 1987

Published online by Cambridge University Press:

28 April 2020, pp. 28-33

Print publication:

1987
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Baseline ACTH values were assessed in a large sample of depressed patients to establish correlations with baseline and post-dexamethasone cortisol levels. No statistically significant differences were found, indicating that excessive ACTH release mighl not be responsible for the elevated cortisol levels and nonsuppression by dexamethasone frequently observed in these patients. Other extrahypophyseal factors may mediate these responses.