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1 results

  • Chapter 16 - Peripheral Neuropathies

  • Edited by David R. Gambling, University of California, San Diego, M. Joanne Douglas, University of British Columbia, Vancouver, Grace Lim, University of Pittsburgh
  • Book:
    Obstetric Anesthesia and Uncommon Disorders
    Published online:
    26 January 2024
    Print publication:
    01 February 2024, pp 259-272

  • Summary

    Peripheral neuropathy takes many forms and occurs as a primary condition or as a component of diseases with multisystem manifestations. There are manifold etiologies, including genetic, inflammatory, traumatic/compressive, metabolic, vasculitic, neoplastic, dietary, and toxic/drug-induced. They are classified as mononeuropathy, multifocal neuropathy (mononeuropathy multiplex), or polyneuropathy. Peripheral neuropathies affect the cell body and the axon (neuropathy, axonopathy) or the myelin sheath (demyelinating neuropathy/neurapraxia). Neuropathies affect sensory, motor, autonomic nerves, or a combination. Pregnancy exacerbates some neuropathies, while pregnancy or parturition may be a direct or indirect cause of a variety of mononeuropathies and plexopathies. A peripheral neuropathy does not directly impact anesthetic care but associated systemic disease manifestations can complicate peripartum anesthetic care. Some peripheral neuropathies alter drug sensitivity or impair respiration, presenting unique challenges to the anesthesiologist.