This article examines the pioneering contributions of a generation of women civil servants, diplomats, and intellectuals—referred to as Cepalinas—to economic thought at the United Nations Economic Commission for Latin America and the Caribbean (CEPAL) between the late 1960s and early 1980s. These women experts, including statisticians, economists, sociologists, and demographers, played a critical role in reshaping CEPAL’s development agenda by advocating for the integration of gender perspectives into regional policies. Through extensive fieldwork and data collection, they highlighted the economic and social contributions of women, particularly those from marginalised communities, and challenged the prevailing male-dominated models of development. Despite the progress made following the 1975 UN International Conference on Women, the Cepalinas often remained on the periphery of institutional power and have been largely overlooked in the historiography. This article brings their work to the forefront, analysing their publications and mission reports to reveal how their efforts transformed both the Commission’s economic frameworks and broader global development policies.