Eight POST herbicides were evaluated alone or in various mixtures for spiny amaranth control in peanut in 1991 and 1992. Acifluorfen alone or in combination with bentazon, lactofen alone, or 2,4-DB alone applied late POST controlled spiny amaranth more than 80% at an early season rating. Lactofen applied early POST and 2,4-DB applied late POST controlled more than 90% late season. Imazethapyr and AC 263,222 controlled 72 to 90% of spiny amaranth, whereas bentazon and pyridate failed to provide adequate control.