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Inequality in iron and folic acid consumption and dietary diversity in pregnant women following exposure to maternal nutrition interventions in three low- and middle-income countries

Published online by Cambridge University Press:  24 May 2024

Deepali Godha*
Affiliation:
Consultant for Alive & Thrive Initiative, FHI Solutions, FHI 360, Indore, MP, India
Sandra Remancus
Affiliation:
Alive & Thrive Initiative, FHI 360, Washington DC, USA
Tina Sanghvi
Affiliation:
Alive & Thrive Initiative, FHI 360, Washington DC, USA
*
*Corresponding author: Email [email protected]
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Abstract

Objective:

Research is available on improved coverage and practices from several large-scale maternal nutrition programmes, but not much is known on change in inequalities. This study analyses wealth and education inequality using Erreygers and Concentration indices for four indicators: adequate iron and folic acid (IFA) consumption, women’s dietary diversity, and counselling on IFA and dietary diversity.

Design:

A pre-test–post-test, control group design.

Setting:

Maternal nutrition intervention programmes conducted in Bangladesh, Burkina Faso and Ethiopia during 2015–2022.

Participants:

Recently delivered women (RDW) and pregnant women (PW).

Results:

Statistically significant reductions in education inequality were observed for adequate IFA consumption, counselling on IFA and dietary diversity in intervention areas of Bangladesh and for adequate IFA consumption in intervention areas of Burkina Faso.

A significant decrease in wealth inequality was observed for adequate IFA consumption in the intervention areas of Bangladesh, whereas a significant increase was observed in the non-intervention areas for counselling on IFA in Ethiopia and for dietary diversity in Burkina Faso.

Conclusion:

The results can be attributed to the extensive delivery system at community level in Bangladesh and being predominantly facility-based in Burkina Faso and Ethiopia. COVID-19 disruptions (in Burkina Faso and Ethiopia) and indicator choice also had a role in the results.

The main takeaways for nutrition programmes are as follows: (a) assessing inequality issues through formative studies during designing, (b) monitoring inequality indicators during implementation, (c) diligently addressing inequality through targeted interventions, setting aside resources and motivating frontline workers to reduce disparities and (d) making inequality analysis a routine part of impact evaluations.

Type
Research Paper
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution and reproduction, provided the original article is properly cited.
Copyright
© The Author(s), 2024. Published by Cambridge University Press on behalf of The Nutrition Society

Several large-scale maternal(Reference Sanghvi, Nguyen and Ghosh1) and child(Reference Victora, Barros and Assunção2) nutrition programmes have been successfully integrated into public health systems and child development initiatives. While these programmes were evaluated on nutrition coverage, impact, cost-effectiveness and implementation issues like integration and scaling-up(Reference Victora, Barros and Assunção2Reference Gwatkin, Rutstein and Johnson4), the extent to which they affected wealth and education inequality is not known. The literature on poverty and health equality shows that despite aggregate improvements in maternal and child health and nutrition coverage and practices, disparities among groups often continue and may even widen(Reference Gwatkin, Rutstein and Johnson4). A review of nutrition interventions, including those for pregnant women (PW), integrated into public health systems in low- and middle-income countries, particularly nutrition education and counselling (twenty-five studies) and micronutrient supplementation (forty-seven studies) lamented the ‘lack of attention to equity of intervention coverage’(Reference Menezes, Lelijveld and Wrottesley5). The Global Nutrition Report 2020 asserts that achieving Sustainable Development Goals (SDGs) and the 2025 global nutrition goals will require both multifaceted and equitable nutrition interventions(6). The aforementioned study and report speak of wealth equity, a term that indicates equal utilisation across wealth groups standardised by need. Wealth equality, on the other hand, indicates equal utilisation across wealth groups without the standardisation by need. This study utilised equality (rather than equity) measures to understand and improve the design and implementation of nutrition programmes for reducing inequality.

The few studies that have looked at disparities in nutrition programmes have focused on the broader issue of nutritional status rather than intervention coverage(Reference Leventhal, Crochemore-Silva and Vidaletti7Reference Yang, Liu and Zha11) Most of the previous studies have used the slope index of inequality and relative index of inequality to analyse inequality. Of the two regression-based indices, slope index of inequality measures the absolute change in health level between the most and the least disadvantaged socio-economic group, while relative index of inequality measures the ratio of health outcome between the bottom and top of the socio-economic levels(Reference Regidor12,Reference Renard, Devleesschauwer and Speybroeck13) . It should be noted that these group-based indices describe inequality across the whole population while also accounting for the size of each group and can be compared across groups if their composition remains the same. However, two important drawbacks need to be considered. (1) Researchers warn against using these indices for policy inferences as they are not appropriate for comparison if socio-economic composition of population changes across or within these groups(Reference Renard, Devleesschauwer and Speybroeck13). For example, when education is used as a solution to improve inequality, the increase in education levels leads to people moving from the uneducated group to the educated groups, thereby changing the composition of the groups. (2) The aforementioned studies have used linear and logistic regression models to estimate the indices. As Moreno-Betancur et al. (Reference Moreno-Betancur, Latouche and Menvielle14) have successfully pointed out the error in doing so, the estimation method changes with the type of parameter studied and the study design; and methodological issues such as model fit to the data become important. According to them, ideally time-to-event data should be used for such estimations and in case of cross-sectional data, negative binomial regression should be used. So far, none of the studies using slope index of inequality and relative index of inequality have explained the limitations in using them and so the practice continues.

Rank-dependent indices such as Erreygers index (EI) and Concentration index (CI) do not have these limitations. They capture all the information by ranking individuals (rather than groups) across the whole spectrum of household wealth (or mother’s education) in the study population from cross-sectional data and correlate it to levels of health(Reference Erreygers and Kessels15). This allows analysing even nuances due to minor differences in wealth between households (or mother’s education). As with slope index of inequality and relative index of inequality derived by regression techniques, the calculation of EI and CI allows consideration of ties in ranking between households (or mothers) in cross-sectional data. A point worth noting is that the indices are calculated differently for binary indicators (yes/no: EI) and continuous indicators (those having a range: CI). Some studies have used CI to analyse inequality for binary indicators(Reference da Silva, França and Barros8,Reference Reyes Matos, Mesenburg and Victora9) , but CI is not the right methodological choice for such bounded variables(Reference Erreygers and Kessels15). To our knowledge, empirical analysis of inequality in nutrition programmes using EI for binary variables and CI for continuous variables has not been done so far.

The aim of the paper is to assess whether disparities in coverage existed after intervention exposure and if the disparities were different among three countries – Bangladesh, Burkina Faso and Ethiopia. We examine the findings of large-scale maternal nutrition programmes from an equality lens using superior econometric techniques that have never been used before to our knowledge, to explore maternal nutrition inequality. The intervention package included iron and folic acid (IFA) supplementation and counselling to improve maternal IFA intake and dietary diversity. These were delivered through existing antenatal care (ANC) programmes and involved systems strengthening for improving IFA supply chains, facility, and outreach service delivery, building community demand, improving the performance of ANC providers and community health workers through training and supervision, and monitoring. No food or cash subsidies were provided. Training involved counselling skills, adherence, engaging family members and advocating for re-allocation of household budgets, promoting locally available affordable foods, and community mobilisation. Messages for PW and their husbands differed; baby and mothers’ health were the focus for PW and current and future economic costs and benefits, and feasible strategies were the focus for their husbands. Further details of the programmes and interventions can be obtained elsewhere(Reference Sanghvi, Nguyen and Ghosh1,Reference Nguyen, Kim and Sanghvi16Reference Kim, Zagré and Ouédraogo18) .

Methods

We conducted a secondary analysis of data from cross-sectional surveys conducted at baseline and endline by the International Food Policy Research Institute (IFPRI) in Bangladesh, Burkina Faso and Ethiopia. A three-stage sampling was used in the study regions, and districts and clusters were randomly allocated to intervention and non-intervention areas. The same clusters were sampled at endline. The sample size estimation for the original analyses was done separately in each country as per baseline prevalence of IFA consumption among recently delivered women (RDW) and of dietary diversity among PW, at a power of 0·80 and a significance level of 0·05 and thus, was adequately powered to perform separate analysis in the PW and RDW populations(Reference Nguyen, Kim and Sanghvi16Reference Kim, Zagré and Ouédraogo18). The final sample sizes of RDW and PW are shown (Table 1).

Table 1 Sample sizes and survey timing by country

RDW, recently delivered women; PW, pregnant women.

Indicators

We calculated changes in inequality in the four indicators as described below:

  • Adequate IFA consumption indicates whether RDW had consumed IFA for at least 90 days during their most recent pregnancy.

  • The IFA counselling indicator measures the total number of messages received on IFA – this number differed across study countriesFootnote 1 .

  • Dietary diversity indicates whether a woman had consumed at least five out of ten defined food groups on the previous day.

  • The binary indicator for counselling on dietary diversity indicates whether the PW received information on consuming five varieties of food from a health worker during ANC and/or home visits (also during community meetings in Burkina Faso).

Statistical analysis

We used two equality indices after ranking the population by household wealth index scoreFootnote 2 and level of mother’s education. The wealth score, a country’s study-area-specific composite index, was obtained using principal component analysis of a household’s assets, materials used in construction, and access to type of drinking water, toilet, and electricity. Since study areas were basically chosen among the disadvantaged population within each country, where rich and richest did not make much sense, the households were divided into three wealth categories (instead of using the popular categorisation) that merely demarcate the poorest from the slightly better-off.

Though wealth and education are often correlated, the logic behind analysing both wealth and education inequalities was to gain insight into the different country contexts. While study areas were basically chosen among the disadvantaged population within each country, education levels across the study countries were different. For example, the prevalence of secondary or higher education in the study population of Bangladesh was above 11 per cent while it was less than 2 per cent in Ethiopia.

The indices are EI that measures inequality of a binary indicator (such as adequate IFA consumption, maternal dietary diversity and counselling on dietary diversity) and CI that measures inequality for a continuous indicator (such as counselling on IFA consumption)(Reference Erreygers and Van Ourti19). Both indices range from –1 to +1, where the negative values indicate a pro-poor distribution, positive values indicate a pro-better-off distribution and a value of 0 indicates neutral distribution. We used ‘conindex’ in Stata 15.1 and standard errors using the cluster sandwich estimator(20). The difference in indices across surveys was tested by F-test that assumes equal variance. An explanation of the observed difference in indices has been attempted with prevalence estimates in the supplemental figures along with the text.

Results

Table 2 shows the population characteristics of RDW and PW at baseline for each country. In Bangladesh, three out of five RDW and PW belonged to the better-off wealth tertile, while in Ethiopia more than half the RDW belonged to the better-off wealth tertile. The proportion of PW who were adolescents was 27 per cent in Bangladesh and 13 per cent in Burkina Faso. About 12 per cent of PW had not attended school in Bangladesh, whereas this estimate was about 57 per cent in Burkina Faso. The parity distribution was balanced in Bangladesh, but the majority of RDW in Burkina Faso and Ethiopia had three or more children. Most women were housewives in Bangladesh and farmers in Burkina Faso and belonged to other occupations in Ethiopia. Bangladesh had the lowest utilisation levels of formal maternal health services at the time of the surveys. Four or more ANC visits were almost universal in Burkina Faso and Ethiopia, but the prevalence in Bangladesh was 66 per cent. The prevalence of institutional deliveries was 38 per cent in Bangladesh, 92 per cent in Burkina Faso and 77 per cent in Ethiopia. Different baseline levels of nutrition outcome indicators can be seen in adequate IFA consumption that was highest in Burkina Faso at 72 per cent and lowest in Bangladesh at 56 per cent. Similarly, mean messages on IFA counselling were also higher in Burkina Faso and Ethiopia as compared to Bangladesh. On the other hand, the prevalence of maternal dietary diversity and counselling on dietary diversity was much higher in Bangladesh as compared to the other study countries. Counselling on dietary diversity was very low in Burkina Faso at 5·63 per cent. Higher baseline levels indicate less room for improvement.

Table 2 Population characteristics at baseline, by country, RDW and PW

RDW, recently delivered women; PW, pregnant women; No., unweighted numbers; Col%, Column %; NA, not applicable; na, information not available.

Table 3 presents the indices on wealth inequality by nutrition indicator in intervention and non-intervention areas at baseline and endline. In intervention areas of Bangladesh, absolute wealth inequality in adequate IFA consumption became less pro-rich at endline as compared to baseline. This can be seen in the reduction in EI to almost one-third (from 0·149 to 0·052), and the change was statistically significant (for further details, see online supplementary material, Supplemental Figure 1). In Ethiopia, the CI for counselling on IFA increased from baseline to endline in non-intervention areas, and the change was significant. In intervention areas of Ethiopia, counselling on IFA became less pro-rich (CI dropped from 0·166 to 0·090), but the change was not significant (for further details, see online supplementary material, Supplemental Figure 2).

Table 3 Erreygers index and concentration index (ranked by household wealth), by country and indicator

IFA, iron and folic acid.

#Concentration index used.

*Indicates statistically significant difference.

Wealth inequality in maternal dietary diversity declined in Bangladesh in intervention areas from 0·283 at baseline to 0·136 at endline, remained almost unchanged in Burkina Faso, and became more pro-better-off at endline in Ethiopia (0·040–0·162). The changes were not statistically significant except in non-intervention areas of Burkina Faso, where inequality increased significantly (for further details, see online supplementary material, Supplemental Figure 3).

Wealth inequality in receiving counselling on dietary diversity declined to one-fifth in intervention areas of Bangladesh, and it remained pro-poor (–0·101 to –0·019). In intervention areas of Ethiopia, inequality reduced to half, though it remained pro-better-off (0·144–0·068). Wealth inequality declined in intervention areas of Burkina Faso, from almost no difference across wealth categories at baseline (0·004) to favouring the poorest at endline (–0·057). However, none of the changes were statistically significant (for further details, see online supplementary material, Supplemental Figure 4).

Table 4 presents the indices on education inequality by nutrition indicator in intervention and non-intervention areas of study countries at baseline and endline. For adequate IFA consumption, EI when ranked by mother’s education was not significantly different between baseline and endline in non-intervention areas across study countries (for further details, see online supplementary material, Supplemental Figure 5). The change in education inequality in the intervention areas of Bangladesh became less pro-educated (from 0·178 to 0·070) and was significantly different. In intervention areas of Burkina Faso, education inequality for adequate IFA consumption changed from pro-low educated (–0·050) to pro-educated (0·024), and the change was significant. The CI for counselling on IFA declined significantly in the intervention areas of Bangladesh from 0·041 to 0·020 and became less pro-educated (for further details, see online supplementary material, Supplemental Figure 6).

Table 4 Erreygers index and concentration index (ranked by mother’s education), by country and indicator

IFA, iron and folic acid.

#Concentration index used.

*Indicates statistically significant difference.

A significant drop in education inequality for dietary diversity was observed from baseline (0·258) to endline (0·052) in the intervention areas of Bangladesh where it became less pro-educated (for further details, see online supplementary material, Supplemental Figure 7). For counselling on dietary diversity, there was no significant change in education inequality between baseline and endline in non-intervention and intervention areas in any of the study countries (for further details, see online supplementary material, Supplemental Figure 8).

Discussion

Overall, the study shows that there was no generalised shift towards greater equality in intervention areas, even though the overall prevalence of indicators was higher in intervention areas. Yet, although improving equality was not an explicit objective of the programmes, some maternal nutrition indicators were trending towards lower inequality after exposure to nutrition interventions. To our knowledge, this is the first study to explore changes in inequality in maternal nutrition service delivery and uptake of practices by PW following intervention programmes. The study is unique in assessing inequality using pre-test–post-test randomised intervention and control group evaluation data from low- and middle-income countries. Though no attempt has been made to imply causality, the strong study design allows our conclusion regarding the possible inequality lowering effect of nutrition interventions to be potentially valid and worth pursuing. We examined inequality by PW’s education in addition to wealth; the study therefore also adds to the literature by providing empirical evidence on education inequality.

As summarised in Table 5, statistically significant reductions in education inequality were observed for adequate IFA consumption, counselling on IFA and dietary diversity in intervention areas of Bangladesh, and for adequate IFA consumption in intervention areas of Burkina Faso. While wealth inequality in adequate IFA consumption decreased over time in the intervention areas in all three countries, it increased for counselling on IFA in Bangladesh and Burkina Faso. This indicates the need for more targeted studies on barriers to counselling services among the less advantaged PW. The lack of alignment in results for IFA consumption and IFA counselling in Bangladesh and Burkina Faso suggests that IFA consumption cannot be attributed only to IFA counselling. This is consistent with studies on factors influencing IFA intake(Reference Sununtnasuk, D’Agostino and Fiedler21).

Table 5 Summary table showing change in inequality (absolute) in maternal nutrition indicators after programme exposure in non-intervention and intervention areas

SE variable, socio-economic variable; Non-Int., non-intervention; Int., intervention.

# Concentration index used.

* indicates statistically significant difference.

Wealth equality declined significantly at endline in the non-intervention group for counselling on IFA in Ethiopia and dietary diversity in Burkina Faso, but not in the intervention group. This may be considered a protective effect of the interventions as the period between baseline and endline was marked by COVID-19 disruptions in Burkina Faso and Ethiopia. For dietary diversity and counselling on dietary diversity, variable results were observed in inequality by wealth and education. For example, during the programme implementation period, inequality declined in Bangladesh while it increased in Burkina Faso and Ethiopia. The timing of COVID-19 coincided with the intervention period in Burkina Faso and Ethiopia but not in Bangladesh(Reference Nguyen, Kim and Sanghvi16,Reference Kim, Sununtnasuk and Worku17,Reference Kim, Ganaba and Menon22) . In addition, the much poorer maternal education in Burkina Faso as compared to Bangladesh might have played a role.

Though the same package of globally recommended interventions was implemented in all three countries, adapting it to existing health systems and local contexts resulted in variations. This and external factors, such as disruptions due to COVID-19 and content of some indicators, were likely explanatory factors for the differing results across countries. Baseline variations among the countries could have limited the potential to improve the prevalence of nutrition indicators where prevalence levels were already high. Since the nutrition interventions were integrated into ANC services, issues with inequality in ANC at baseline may reflect the underlying ANC service delivery platforms as noted below.

First, the structures of ANC platforms varied from a community-based NGO programme in Bangladesh to a primary health centre-based government programme in Burkina Faso, and a primary health centre plus health post-based government programme in Ethiopia. With regard to functioning, the Bangladesh model used a ‘performance improvement cycle’ to build nutrition service provision more comprehensively, while the Burkina Faso model focused primarily on health systems strengthening to improve ANC services with linkages to community health agents. The Ethiopia model focused on capacity building of selected health systems components, including supplies, monitoring, and ANC providers at primary health centre hubs and in health posts along with imparting key messages through group sessions and home visits by health extension workers and volunteers(Reference Sanghvi, Nguyen and Ghosh1).

Second, economic constraints and geographic barriers were addressed differently. In Bangladesh, IFA tablets were made free in intervention areas and female community health volunteers delivered IFA and counselling to the PWs’ doorsteps(Reference Sanghvi, Nguyen and Ghosh1). On the other hand, though IFA tablets and facility visits were made free in both Burkina Faso and Ethiopia and services were brought nearer to the community in Ethiopia by permitting health extension workers to deliver ANC services at the health post level, PW were still required to visit health facilities to collect them and receive counselling, thereby benefitting only those women who had time, resources, and family support to make facility visits.

Third, community agents in Burkina Faso and Ethiopia were remunerated through fixed monthly salaries and were not linked to coverage or quality criteria. In contrast, community volunteers in Bangladesh were provided performance-based cash incentives, with clearly structured criteria including reaching as many PW as possible. This may have motivated community volunteers to make extra efforts in reaching distant and less receptive households.

Fourth, in Bangladesh, additional special forums were organised for husbands of PW through outreach sessions at convenient sites and at times convenient for them. Husbands played a pivotal role in each country in facilitating PW attendance at ANC sessions and in the uptake of PW’s IFA consumption and dietary diversity. Similar forums were not successful in Burkina Faso because the staff found it difficult to identify the right venues to reach husbands of PW consistently with high coverage. In Ethiopia, no special gatherings for husbands were used; instead, home visits were made and other family members present in the household were engaged.

As noted above, despite a common package of interventions, the strategies used for service delivery differed and may account for more reductions in inequality in Bangladesh as compared to Burkina Faso and Ethiopia(Reference Leventhal, Crochemore-Silva and Vidaletti7,Reference Kavle and Landry23) . While Tables 35 show that inequality in Bangladesh reduced in intervention areas at endline as compared to baseline, Figures 18 in the supplemental material show how this came about. The prevalence among the poorest increased to almost the same extent as the better-off. While the first three bars representing prevalence at baseline and non-intervention areas at endline remained almost the same, the increase in prevalence (fourth bar) in intervention areas at endline is drastic. This change is higher in the poorest section as compared to the less poor and better-off. Our results align with an analysis of eighteen RMNCH indicators in thirty-six low-income and middle-income countries that found community-based interventions had a more equitable distribution and those primarily delivered in health facilities did not(Reference Leventhal, Crochemore-Silva and Vidaletti7). Similarly, past research suggests that ANC attendance in facilities and high-quality ANC services tend to favour the better-off(Reference Amo-Adjei, Aduo-Adjei and Opoku-Nyamaah24). A review of counselling services in South Asian countries found that poor households and those utilising lower level or public health facilities were less likely to receive counselling than wealthier households or those utilising higher levels of government facilities or private facilities(Reference Torlesse, Benedict and Craig25).

COVID-19 disruptions also had a role in the Burkina Faso and Ethiopia results. The epidemic took a heavy toll on the delivery and utilisation of ANC due to interrupted services in Ethiopia and on household food security due to high food prices in Burkina Faso and Ethiopia during programme implementation(Reference Osendarp, Akuoku and Black26). In contrast, maternal nutrition interventions in Bangladesh were implemented and evaluated during 2015–2016, preceding COVID-19 restrictions, and were conducted following a period of economic growth and overall food availability(Reference Ahmed, Bakhtiar and Ali27). The incorporation of multiple components in the community-based intervention was a successful strategy deployed by Bangladesh, as well(Reference Browne, Adams and Atkinson28).

The type of PW behaviour also had a bearing on the study results, with IFA consumption responding to interventions better than dietary diversity. Relatively greater effort and costs were likely to have been incurred in improving dietary diversity at the household and individual levels, for example, for shifting embedded gender norms and perceptions of family members to increase specified foods and meals for PW, while IFA was available free of cost and could be obtained through public health services. For service delivery costs, ensuring IFA supplies and improving health providers’ IFA distribution and counselling performance are likely to require less effort as compared to efforts to alter household budgets and food allocation for PW.

Limitations

The study results are subject to the following limitations. (1) Absence of information on survey weights prevented significance testing in changes (difference-in-difference) in inequality indices. Instead, a cluster sandwich estimator was used. (2) Though the simplistic conceptualisation of counselling on dietary diversity did not do justice to the full contents of counselling that also covered food quantity and meal frequency and tailoring of messages to individual client needs, it was an indication of efforts made to modify PW diets. In addition, the conceptualisation disregards other factors that influence the quality of counselling including (but not limited) to training, mentoring and counselling materials. In future, better measures of counselling quality need to be developed. (3) In Bangladesh, education inequality used education categories for ranking because of a lack of yearly information on mother’s education. It has been suggested that multiple ties in the fractional ranking of the education variable may be problematic(Reference Chen and Roy29), but the Stata command ‘conindex’ takes care of these ties in computing the point estimate while the ‘cluster’ option takes care of ties between non-independent observations(Reference O’Donnell, O’Neill and Van Ourti30). (4) In Ethiopia, there was the absence of consolidated information on the total number of IFA consumed in baseline datasets of RDW and on education in baseline datasets of both RDW and PW datasets, so only endline was used. (5) Note that some estimates are based on sample sizes as low as 86 (Ethiopia PW baseline data). Though there are no guidelines on sample sizes and index calculations are based on cumulative means and do not require large sample sizes, estimate precision increases with larger samples. (6) It should be noted that dividing household wealth into three equal-sized groups or wealth tertiles incorporates only the concept of relative poverty because most of the respondents belonged to deprived sections of society in rural areas where the programmes were implemented.

Conclusions

The results from three different country and programme contexts provide useful insights into programmatic strategies needed to improve inequality in maternal nutrition interventions which can be helpful in other programmes. Although the programmes were not explicitly designed to reduce inequality, it appears that certain elements of policies and interventions helped in improving inequality(Reference Kavle and Landry23,Reference Paudyal, Parajuli and Garcia Larsen31,Reference Ahmed, Chase and Wagnild32) . Pro-poor characteristics of the long-standing community-based MNCH programme in Bangladesh transferred easily to the newly integrated nutrition components; the type of remuneration, competence, experience and commitment of community workers enabled them to more effectively reach the poorest and motivate behaviour change among PW in Bangladesh. This aligns with past research(Reference LeBan, Kok and Perry33) and reinforces the WHO guidance on maintaining community health worker programmes to maximise coverage(Reference Tulenko, Møgedal and Afzal34) and foster equity(Reference Campbell, Buchan and Cometto35). However, this analysis indicates that more needs to be done to explicitly identify and reduce inequality.

Applying inequality analysis across three countries with different contexts provides further insight into the role of health systems’ infrastructure and use of rigorously designed programme interventions as compared to routine intervention packages. The study interventions tailored global recommendations(36) to each context and aimed at improving overall coverage and adoption of nutrition practices, but they were not aimed specifically at reducing inequalities. Large-scale programmes usually focus on improving coverage or usage but do not usually have the objective of reducing inequality. Through this study, we examined whether this approach needs to be enhanced through the explicit introduction of equality strategies. Since inequality is a major hurdle in achieving SDGs, the programme insight gained from this article will be helpful to programmers in future.

According to the 2030 collaboration, reducing inequalities within countries at a faster pace could be one of the ways to achieve SDGs by 2030(37). The main takeaways from this study for nutrition programmes to help countries achieve these goals are as follows: (a) assessing inequality issues early while designing interventions through formative studies, (b) monitoring inequality indicators throughout implementation, (c) diligently addressing inequality through targeted interventions, setting aside resources to address inequality and motivating frontline workers to reach left-out communities and areas, (d) motivating managers and providers to build community linkages and engage family members to drive services, coverage and quality closer to where the disadvantaged reside and (e) making inequality analysis a routine part of impact evaluations.

Acknowledgements

The authors acknowledge the journal reviewers for their insightful comments that have helped in making this study better. The authors are grateful to the International Food Policy and Research Institute for access to evaluation data. This study would not have been possible without the sustained support of the Bill & Melinda Gates Foundation who funded the development and implementation of the programmes described here and funded the analysis under grant number INV-042392, awarded to the Alive & Thrive initiative, Global Nutrition Unit, FHI 360. Under the grant conditions of the Foundation, a Creative Commons Attribution 4.0 Generic License has already been assigned to the Author Accepted Manuscript version that might arise from this submission, see https://creativecommons.org/licenses/by/4.0/.

Financial support

The analysis was funded by the Bill & Melinda Gates Foundation (BMGF) (grant number INV-006546 and INV-042392), awarded to Alive & Thrive initiative, Global Nutrition Unit, FHI 360. BMGF had no role in the design, analysis or writing of this article.

Conflict of interest

None.

Authorship

DG participated in the conceptualisation, data curation, formal analysis, methodology, interpretation, and writing of the original and final drafts of the paper. SR was involved in conceptualisation, funding acquisition, data interpretation, and review and editing. TS conceptualised the study and participated in the literature search, study design, methodology, validation, access to data, data interpretation and writing of sections of the original and final drafts of the paper.

Ethics of human subject participation

This study was conducted according to the guidelines laid down in the Declaration of Helsinki, and all procedures involving research study participants were approved by the Institutional Review Board (IRB) at International Food Policy Research Institute and from the IRB of the study countries. Written/verbal informed consent was obtained from all subjects/patients. Verbal consent was witnessed and formally recorded.

Data sharing

De-identified participant data used for generating the results are accessible through https://www.aliveandthrive.org/en/our-data, linked to https://dataverse.harvard.edu/dataverse/harvard.

Supplementary material

For supplementary material accompanying this paper visit https://doi.org/10.1017/S1368980024001150

Footnotes

1 This is because messages and contact points were tailored to each country context. Messages were received during both ANC and counselling sessions at home visits in Bangladesh; at three different contact points in Burkina Faso: during ANC visits in facilities, home visits and community meetings/GASPA (local term for women’s support groups); and at two different contact points in Ethiopia: during ANC visits in health facilities and home visits. The country specific message list is as follows:

  • Bangladesh : Take 1 tablet daily; IFA prevents anemia; IFA reduces the risk of LBW; IFA reduces the risk of maternal death; do not drink tea/coffee with IFA; and others.

  • Burkina Faso : Take 1 tablet daily; take 180 IFA tablets from the fourth month of pregnancy until delivery; IFA prevents anemia; IFA reduces the risk of LBW; IFA reduces the risk of maternal death; do not to take tea/coffee with IFA; take IFA tablets with water before sleeping at night; eat more fruits and vegetables daily when taking IFA tablets; take two IFA tablets per d/take IFA with or after meals; prevent or manage side effects (only endline) and others.

  • Ethiopia : Take 180 IFA tablets daily during pregnancy; take one IFA tablet per d from the fourth month of pregnancy; IFA prevents anemia; IFA reduces the risk of LBW; IFA reduces the risk of maternal death; not to take tea/coffee with IFA; take IFA tablets with water or lime juice at night; potential side effects; and how to manage those side effects.

2 The wealth index was created using principal component analysis. Variable selection and creation of wealth index has been conducted separately for each country, but it remains the same within a country across non-intervention and intervention areas as well as baseline and endline surveys. Further details are available from the authors.

References

Sanghvi, T, Nguyen, PH, Ghosh, S et al. (2022) Process of developing models of maternal nutrition interventions integrated into antenatal care services in Bangladesh, Burkina Faso, Ethiopia and India. Matern Child Nutr 18, e13379.CrossRefGoogle ScholarPubMed
Victora, CG, Barros, FC, Assunção, MC et al. (2012) Scaling up maternal nutrition programs to improve birth outcomes: a review of implementation issues. Food Nutr Bull 33, S626.CrossRefGoogle ScholarPubMed
Black, MM, Pérez-Escamilla, R & Rao, SF (2015) Integrating nutrition and child development interventions: scientific basis, evidence of impact, and implementation considerations. Adv Nutr 6, 852859.CrossRefGoogle ScholarPubMed
Gwatkin, DR, Rutstein, S, Johnson, K et al. (2007) Socio-economic differences in health, nutrition, and population within developing countries: an overview. Niger J Clin Pract 10, 272282.Google ScholarPubMed
Menezes, R, Lelijveld, N, Wrottesley, SV et al. (2022) Integrating women and girls’ nutrition services into health systems in low- and middle-income countries: a systematic review. Nutrients 14, 4488.CrossRefGoogle ScholarPubMed
Report GN (2020) Action on Equity to End Malnutrition - Global Nutrition Report. Bristol: Development Initiatives Poverty Research Ltd.Google Scholar
Leventhal, DGP, Crochemore-Silva, I, Vidaletti, LP et al. (2021) Delivery channels and socioeconomic inequalities in coverage of reproductive, maternal, newborn, and child health interventions: analysis of 36 cross-sectional surveys in low-income and middle-income countries. Lancet Glob Health 9, e1101e9.CrossRefGoogle ScholarPubMed
da Silva, ICM, França, GV, Barros, AJD et al. (2018) Socioeconomic inequalities persist despite declining stunting prevalence in low- and middle-income countries. J Nutr 148, 254258.CrossRefGoogle ScholarPubMed
Reyes Matos, U, Mesenburg, MA & Victora, CG (2020) Socioeconomic inequalities in the prevalence of underweight, overweight, and obesity among women aged 20–49 in low- and middle-income countries. Int J Obes (Lond) 44, 609616.CrossRefGoogle ScholarPubMed
Wang, M, Gao, H, Wang, J et al. (2022) Global burden and inequality of iron deficiency: findings from the Global Burden of Disease datasets 1990–2017. Nutr J 21, 16.CrossRefGoogle ScholarPubMed
Yang, F, Liu, X & Zha, P (2018) Trends in socioeconomic inequalities and prevalence of anemia among children and nonpregnant women in low- and middle-income countries. JAMA Network Open 1, e182899-e.CrossRefGoogle ScholarPubMed
Regidor, E (2004) Measures of health inequalities: part 2. J Epidemiol Community Health 58, 900903.CrossRefGoogle ScholarPubMed
Renard, F, Devleesschauwer, B, Speybroeck, N et al. (2019) Monitoring health inequalities when the socio-economic composition changes: are the slope and relative indices of inequality appropriate? Results of a simulation study. BMC Public Health 19, 662.CrossRefGoogle ScholarPubMed
Moreno-Betancur, M, Latouche, A, Menvielle, G et al. (2015) Relative index of inequality and slope index of inequality: a structured regression framework for estimation. Epidemiol 26, 518527.CrossRefGoogle ScholarPubMed
Erreygers, G & Kessels, R (2017) Socioeconomic status and health: a new approach to the measurement of bivariate inequality. Int J Environ Res Public Health 14, 673.CrossRefGoogle Scholar
Nguyen, PH, Kim, SS, Sanghvi, T et al. (2017) Integrating nutrition interventions into an existing maternal, neonatal, and child health program increased maternal dietary diversity, micronutrient intake, and exclusive breastfeeding practices in Bangladesh: results of a cluster-randomized program evaluation. J Nutr 147, 23262337.CrossRefGoogle ScholarPubMed
Kim, S, Sununtnasuk, C, Worku, A et al. (2022) A Feasibility Study of Integrating Maternal Nutrition Interventions into Antenatal Care Services in Ethiopia: A Cluster-Randomized Evaluation. Washington, DC: IFPRI.Google Scholar
Kim, SS, Zagré, RR, Ouédraogo, CT et al. (2023) Intensified nutrition interventions in antenatal care services increased consumption of iron and folic acid supplements and early breastfeeding practices in Burkina Faso: results of a cluster-randomized program evaluation. J Nutr 153, 30583067.CrossRefGoogle Scholar
Erreygers, G & Van Ourti, T (2011) Measuring socioeconomic inequality in health, health care and health financing by means of rank-dependent indices: a recipe for good practice. J Health Econ 30, 685694.CrossRefGoogle ScholarPubMed
StataCorp (2017) Stata Statistical Software: Release 15.1 StataCorp. College Station, TX: StataCorp LLC.Google Scholar
Sununtnasuk, C, D’Agostino, A & Fiedler, JL (2016) Iron+folic acid distribution and consumption through antenatal care: identifying barriers across countries. Public Health Nutr 19, 732742.CrossRefGoogle ScholarPubMed
Kim, S, Ganaba, R, Menon, P et al. (2022) Strengthening nutrition interventions in antenatal care services improved consumption of iron-folic acid supplements and early breastfeeding practices in Burkina Faso. Curr Dev Nutr 6, 674.CrossRefGoogle Scholar
Kavle, JA & Landry, M (2018) Community-based distribution of iron-folic acid supplementation in low- and middle-income countries: a review of evidence and programme implications. Public Health Nutr 21, 346354.CrossRefGoogle ScholarPubMed
Amo-Adjei, J, Aduo-Adjei, K, Opoku-Nyamaah, C et al. (2018) Analysis of socioeconomic differences in the quality of antenatal services in low and middle-income countries (LMICs). PLoS One 13, e0192513.CrossRefGoogle ScholarPubMed
Torlesse, H, Benedict, RK, Craig, HC et al. (2021) The quality of maternal nutrition and infant feeding counselling during antenatal care in South Asia. Matern Child Nutr 17, e13153.CrossRefGoogle ScholarPubMed
Osendarp, S, Akuoku, JK, Black, RE et al. (2021) The COVID-19 crisis will exacerbate maternal and child undernutrition and child mortality in low- and middle-income countries. Nat Food 2, 476484.CrossRefGoogle ScholarPubMed
Ahmed, AU, Bakhtiar, MM, Ali, M et al. (2022) Trends and inequities in food, energy, protein, fat, and carbohydrate intakes in rural Bangladesh. J Nutr 152, 25912603.CrossRefGoogle ScholarPubMed
Browne, J, Adams, K, Atkinson, P et al. (2018) Food and nutrition programs for aboriginal and Torres Strait Islander Australians: an overview of systematic reviews. Aust Health Rev 42, 689697.CrossRefGoogle ScholarPubMed
Chen, Z & Roy, K (2009) Calculating concentration index with repetitive values of indicators of economic welfare. J Health Econ 28, 169175.CrossRefGoogle ScholarPubMed
O’Donnell, O, O’Neill, S, Van Ourti, T et al. (2016) conindex: estimation of concentration indices. Stata J 16, 112138.CrossRefGoogle ScholarPubMed
Paudyal, N, Parajuli, KR, Garcia Larsen, V et al. (2022) A review of the maternal iron and folic acid supplementation programme in Nepal: achievements and challenges. Matern Child Nutr 18, e13173.CrossRefGoogle ScholarPubMed
Ahmed, S, Chase, LE, Wagnild, J et al. (2022) Community health workers and health equity in low- and middle-income countries: systematic review and recommendations for policy and practice. Int J for Equity Health 21, 49.CrossRefGoogle ScholarPubMed
LeBan, K, Kok, M & Perry, HB (2021) Community health workers at the dawn of a new era: 9. CHWs’ relationships with the health system and communities. Health Res Policy Syst 19, 116.CrossRefGoogle ScholarPubMed
Tulenko, K, Møgedal, S, Afzal, MM et al. (2013) Community health workers for universal health-care coverage: from fragmentation to synergy. Bull World Health Organ 91, 847852.CrossRefGoogle ScholarPubMed
Campbell, J, Buchan, J, Cometto, G et al. (2013) Human resources for health and universal health coverage: fostering equity and effective coverage. Bull World Health Organ 91, 853863.CrossRefGoogle ScholarPubMed
WHO (2016) Who Recommendations on Antenatal Care for a Positive Pregnancy Experience. Geneva, Switzerland: WHO.Google Scholar
Countdown to 2030 Collaboration (2018) Countdown to 2030: tracking progress towards universal coverage for reproductive, maternal, newborn, and child health. Lancet 391, 15381548.CrossRefGoogle Scholar
Figure 0

Table 1 Sample sizes and survey timing by country

Figure 1

Table 2 Population characteristics at baseline, by country, RDW and PW

Figure 2

Table 3 Erreygers index and concentration index (ranked by household wealth), by country and indicator

Figure 3

Table 4 Erreygers index and concentration index (ranked by mother’s education), by country and indicator

Figure 4

Table 5 Summary table showing change in inequality (absolute) in maternal nutrition indicators after programme exposure in non-intervention and intervention areas