We commence this, the last issue of the century, nay the
millennium, with a timely annotation by Overmeyer and
Taylor on one of the most controversial topics in child
psychiatry at present. As the diagnosis of ADHD (or, in
its more limited diagnostic form, hyperkinetic disorder)
becomes ever more widely recognised in all corners of the
world, the use of medical management to control young
children (mainly boys) whose behaviour irritates parents
and teachers alike is growing almost exponentially. The
authors provide a valuable review of the use of medication
for hyperkinetic/ADHD disorders. They point out that
the use of stimulants can reduce the severity of symptoms,
although they acknowledge that merely suppressing those
symptoms will not necessarily affect the prognosis; there
is no evidence that long-term outcome is better for
medically treated individuals. It has now been shown by
several trials that medication can be relatively more
effective than behavioural treatments alone: however,
this conclusion should not be taken as a license to
prescribe medication as a first line of treatment in all
circumstances and at all ages. It is worth bearing in mind
that methylphenidate and dexamphetamine are the only
drugs licensed in the United Kingdom for the treatment
of hyperactivity. The review also discusses the use of
pemoline (now unlicensed in the United Kingdom because of risk
of liver damage), antidepressants, and
clonidine. It does not mention risperidone, which has
recently attracted a certain vogue amongst private
paediatric practitioners. Risperidone does not yet have an
evidence base, but it is less prone to induce extra-pyramidal symptoms than other neuroleptics such as
haloperidol. It is not, however, free of hazards, which
include obesity and endocrinological disorders. Interestingly,
the “elimination diet” that every other parent
seemed to be demanding for their “hyperactive” child a
few years ago has gone out of fashion, presumably
because there was hardly any convincing evidence that it
was beneficial in the first place.