LEARNING OBJECTIVES
After reading this article you will be able to:
• list the variety of mental illnesses for which strong evidence exists to support the use of EMDR
• understand the specific applications of EMDR in affective, anxiety, psychotic and somatic disorders
• identify the areas in which further evidence is still needed to support the use of EMDR.
In our previous article in BJPsych Advances (Udo Reference Udo, Javinsky and Awani2022) we presented the process of conducting eye movement desensitisation and reprocessing (EMDR) therapy and discussed the approved indications for its use and evidence supporting EMDR for post-traumatic stress disorder (PTSD). In the present article, we discuss the various mental and associated physical health conditions for which EMDR may be useful. A key element of EMDR is that it views psychopathology through the adaptive information processing model, which suggests that mental illness can result from improperly processed trauma memories (Solomon Reference Solomon and Shapiro2008). EMDR is therefore a transdiagnostic intervention that can be used in many psychiatric disorders. The conditions chosen for discussion in this article are those underpinned by randomised controlled trials (RCTs) or where EMDR is included in treatment guidelines. It is hoped that readers will become aware that, apart from PTSD, EMDR may be used to improve the quality of treatment in various other conditions, both mental and physical. There are other conditions with only lower-level evidence, such as case reports, case series or expert opinions, but these are not the subject of this review.
Anxiety disorders
Panic disorder
Research investigating the efficacy of EMDR in treating anxiety disorders has largely focused on panic disorder, with several case studies, one controlled non-randomised trial and three RCTs supporting its use.
The case studies (Fernandez Reference Fernandez and Faretta2007; Bhagwagar Reference Bhagwagar2016; Trlin Reference Trlin and Hasanovic2021) have described EMDR as being effective in reducing symptoms associated with panic disorder.
In the non-randomised trial, by Faretta (Reference Faretta2013), 19 participants with panic disorder with and without agoraphobia received 12 sessions of either EMDR or cognitive–behavioural therapy (CBT). Both EMDR and CBT were found to be effective, with no significant differences between the two therapies, aside from a lower frequency of panic attacks in EMDR-treated participants. These results were maintained at the 1-year follow-up.
In an RCT by Feske & Goldstein (Reference Feske and Goldstein1997), 43 people with panic disorder were randomly assigned to either six sessions of EMDR, six sessions of EMDR without the eye movements (eye fixation exposure and reprocessing, EFER) or to a waiting list. Compared with the waiting list, EMDR resulted in significant reductions in panic and panic-related symptoms. When compared with EFER, EMDR was more effective in improving scores on two of five primary measures, specifically the Agoraphobia–Anticipated Panic-Coping Composite and General Anxiety–Fear of Panic Composite, as well as on secondary measures of depression and social adjustment; however, this difference did not remain significant at 3-month follow-up, suggesting that the eye movement component of EMDR might not be necessary for panic disorder. A subsequent RCT by Goldstein et al (Reference Goldstein, De Beurs and Chambless2000) assigned 46 individuals with panic disorder with agoraphobia to one of three groups: EMDR, association and relaxation therapy (ART) or a waiting list. Compared with the waiting list, EMDR resulted in significant improvements on measures of severity of anxiety, panic disorder and agoraphobia but made no difference in the frequency of panic attacks or anxious cognitions. Furthermore, there were no significant differences between the EMDR and ART groups, a result that remained at 1-month follow-up. Following this, an RCT by Horst et al (Reference Horst, den Oudsten and Zijlstra2017) was more promising. A total of 84 participants with panic disorder were assigned to receive 13 weekly 60 min sessions of either CBT or EMDR. The results suggested non-inferiority of EMDR to CBT on two of three measures of panic disorder severity and on the measure of quality of life, while the third measure of panic disorder severity was inconclusive. The authors therefore concluded that EMDR proved to be as effective as CBT for treating people with panic disorder.
Specific phobias
Two RCTs have evaluated whether EMDR is an effective treatment for specific phobia. A study by Doering et al (Reference Doering, Ohlmeier and de Jongh2013) randomly assigned 31 individuals who met DSM-IV-TR criteria for dental phobia to either three EMDR sessions targeting memories of negative dental events or a waiting list. EMDR was associated with significant reductions in dental anxiety and avoidance behaviour, findings that were maintained at both the 3-month and 1-year follow-ups. After 1 year, 83.3% of the EMDR group were in regular dental treatment. An RCT by Triscari et al (Reference Triscari, Faraci and Catalisano2015) assessed the efficacy of CBT combined with EMDR in treating flight anxiety (fear of flying). They randomised 65 individuals to receive either CBT combined with systematic desensitisation, CBT combined with EMDR therapy or CBT combined with virtual reality exposure therapy. All three groups experienced significant decreases on scales measuring flight anxiety, with results maintained at 1-year follow-up and no significant differences between groups.
Generalised anxiety disorder
Presently, no RCTs have evaluated the use of EMDR in generalised anxiety disorder (GAD). In two preliminary studies (Gauvreau Reference Gauvreau and Bouchard2008; Farima Reference Farima, Dowlatabadi and Behzadi2015), small samples of individuals with GAD completed several sessions of EMDR. Both studies found a significant reduction in symptoms of anxiety and excessive worry, which were maintained at 1- and 2-month follow-up respectively. Furthermore, Gauvreau et al reported that two of their four participants achieved full remission from GAD, and Farima et al found that EMDR increased tolerance of uncertainty.
Symptoms of anxiety disorder
Finally, Yunitri et al (Reference Yunitri, Kao and Chu2020) completed a meta-analysis to evaluate the overall effectiveness of EMDR in reducing symptoms of anxiety disorder. Their results, having analysed 17 studies, showed that EMDR was associated with a significant reduction in anxiety, panic, phobia and behavioural/somatic symptoms. Subgroup analysis revealed greater effects of EMDR when compared with passive control conditions. These effects were found not to differ significantly with the duration or number of sessions. The authors thus concluded that EMDR is efficacious in reducing symptoms associated with anxiety disorder.
Obsessive–compulsive disorder
EMDR has not been recommended as a treatment for obsessive–compulsive disorder (OCD) in any major guidelines, and research into its use is still in its early stages. Marsden et al (Reference Marsden, Lovell and Blore2018a) performed an RCT comparing EMDR and the recommended treatment, CBT. Their study randomised 55 individuals to each treatment. Both treatments had comparable completion rates and clinical outcomes, with no significant differences between the groups. Participants were recruited from a primary care mental health service that routinely offered 16–20 sessions of CBT, suggesting that their psychopathology may not have been severe. The basis for the application of EMDR was Marr's (Reference Marr2012) hypothesis that it can be used to process the fears and obsessive behaviours of OCD, thereby reducing distress in the present. He also hypothesised that EMDR could be used to process emotions associated with the trigger event or underlying event linked to the onset of illness. Marsden et al followed Marr's EMDR sequential protocol, which involved processing current triggers for obsessions and compulsions, generating a psychological belief of future success and then processing any past disturbing events. Their study is limited by its sample size and a brief follow up period of 6 months.
Nazari et al's (Reference Nazari, Momeni and Jariani2011) RCT compared EMDR with treatment using citalopram, a selective serotonin reuptake inhibitor (SSRI). In their study, 90 individuals were randomly assigned to the two groups and received the interventions for 12 weeks. Comparisons were made before and after, which showed a significant post-treatment drop in symptoms in the EMDR group compared with the citalopram group. The authors concluded that both methods brought about improvement in obsessive–compulsive symptoms, with short-term EMDR having better outcomes. Their study was limited by a short follow-up of participants, low dose of citalopram (20 mg daily) and no record of side-effects of interventions. In addition, 17 participants from the citalopram group and 13 from the EMDR group were lost to follow-up and not included in the final analysis. The range or median number of sessions required for EMDR therapy was not clear.
Böhm (Reference Böhm2019) carried out a narrative review of studies of EMDR treatment of OCD. It included the two studies above as the only randomised trials available at the time. In addition, case studies were reviewed which showed the successful integration of EMDR with CBT strategies for treatment of refractory OCD. Furthermore, a small study by Keenan et al (Reference Keenan, Farrell and Keenan2018) showed that EMDR was effective in treating people with OCD who were still symptomatic after having previously undergone CBT. Eight patients who had not benefitted from exposure and response prevention therapy completed eight sessions of EMDR, after which they demonstrated a decrease in their OCD symptoms both 1 and 3 months later; however, the authors did not do any formal statistical testing to be able to comment on significance.
Marsden et al (Reference Marsden, Teahan and Lovell2018b) considered the experiences of a sample of 24 participants in their above-mentioned RCT comparing EMDR and CBT (Marsden Reference Marsden, Lovell and Blore2018a). A thematic analysis of interviews showed that half of the 14 in their sample who had received EMDR struggled to recall the name of the treatment and its rationale; however, many felt that the preparatory phases before actual processing were of good use. Some of the EMDR participants were able to work satisfactorily with the bilateral stimulation device, but some complained of experiencing drowsiness, exhaustion and nausea. Other difficulties that EMDR participants encountered were inability to locate an OCD trigger memory, inability to relive real-world anxiety in the therapy space and exacerbation of checking behaviours after finishing therapy. Difficulties described by participants in the CBT group included problems performing exposures at the beginning of therapy and during graded activities; finding the sessions too structured and inflexible; and inability to express their feelings, leading to eventual drop out from CBT. The authors thought that the acceptability and tolerability of treatment methods depended largely on how credible patients found the rationale behind each treatment. In his seminal book Persuasion and Healing: A Comparative Study of Psychotherapy, Frank (Reference Frank1961) asserts that one of the common characteristics of efficacious psychotherapies is the use of rationales that provide reasonable explanations for patients’ symptoms and proposes procedures for resolving them.
Mood disorders
Depression
Multiple RCTs assessing EMDR as a treatment for depression have been conducted, with sessions focusing on reprocessing negative memories of stressful life experiences that contributed to the development of depression or negative cognitions associated with reduced functioning. The results of these studies generally support the use of EMDR in treating depression, both as a stand-alone therapy and in addition to other psychotherapies or antidepressant medication.
Hase et al (Reference Hase, Balmaceda and Hase2015) compared outcomes for 16 in-patients with depression who received EMDR plus treatment as usual with a group of 16 controls matched for diagnosis, degree of depression, gender, age and time of admission who received treatment as usual only. Treatment as usual consisted of individual psychodynamic psychotherapy, group therapy sessions and five group sessions of psychoeducation. The EMDR group had a greater overall reduction in depressive symptoms, with 68% of participants achieving full remission of their symptoms. At the 1-year follow-up, those who received EMDR reported fewer problems related to depression and fewer relapses.
Gauhar (Reference Gauhar2016) randomly assigned 26 individuals with depression to either 6–8 sessions of EMDR or a waiting-list control. Results showed significant improvements on all measures of depressive symptoms and quality of life following EMDR therapy, with the number and strength of negative cognitions markedly decreased post-treatment. These results were maintained at 3-month follow-up.
A second RCT by Hase et al (Reference Hase, Plagge and Hase2018) again tested whether adding EMDR to treatment as usual would achieve superior results. The authors randomised 30 in-patients with depression to receive EMDR plus treatment as usual or treatment as usual only. Treatment as usual consisted of psychodynamic or behavioural group therapy, standard individual therapy and antidepressant medication. Patients who received EMDR plus treatment as usual had significantly better scores on the Beck Depression Inventory-II and the Global Severity Index following treatment. Furthermore, 7 out of the 14 patients in the EMDR group achieved full symptom remission, compared with only 4 out of the 16 in the treatment-as-usual only group.
Lastly, an RCT by Ostacoli et al (Reference Ostacoli, Carletto and Cavallo2018) compared EMDR with CBT to assess EMDR's efficacy as an adjunct to antidepressant medication. Eighty-two individuals with depression were randomised to receive 12–18 sessions of either EMDR or CBT in addition to treatment as usual with antidepressant medication. Both groups showed a reduction in depressive symptoms with no significant differences between the two groups, effects that were maintained at the 6-month follow-up.
Overall, the results of these studies suggest that, either alone or as an adjunct, EMDR is a promising option for the treatment of depression, although more research is needed to appropriately integrate it into treatment guidelines.
Bipolar disorder
At present, only one RCT has investigated the use of EMDR in bipolar disorder. Novo et al (Reference Novo, Landin-Romero and Radua2014) randomised 20 individuals with DSM-IV bipolar I or II disorder with subsyndromal mood symptoms and a history of traumatic events to receive either 14–18 sessions of EMDR over 12 weeks or treatment as usual. Those who received EMDR showed a statistically significant improvement in depressive and hypomanic symptoms, symptoms of trauma, and the impact of trauma on functioning compared with the treatment-as-usual group; however, this effect was only partly maintained in trauma impact at the 24-week follow-up. This pilot study therefore suggested that EMDR may be an effective intervention for subsyndromal mood and trauma symptoms in people with bipolar disorder.
Dissociative disorders
Guidelines published by the International Society for the Study of Trauma and Dissociation (2011) identify EMDR as one of the treatments that may be helpful in dissociative identity disorder (DID); however, this recommendation is based on limited, lower-level studies. Included in the guidelines is a paper by Lazrove & Fine (Reference Lazrove and Fine1996) which presents a comprehensive description of how EMDR may be used in DID using a case report. Twombly (Reference Twombly2000) also describes how EMDR may be adapted for people with DID. Paulsen (Reference Paulsen1995) uses cases to illustrate situations where EMDR should not be used or should be cautiously used in people with DID.
The use of EMDR in DID is highly specialised and requires specific training. The majority of evidence for treating this disorder with EMDR takes the form of expert opinions presented at conferences and in the grey literature.
Eating disorders
Traumatic life experiences are known to be one of many etiological factors that may trigger eating disorders. Thus, EMDR may have a role in the treatment of eating disorders; however, the current evidence comprises only case studies and one randomised experimental trial.
Four case studies have provided preliminary evidence supporting EMDR's use. Dziegielewski & Wolfe (Reference Dziegielewski and Wolfe2000) explored the potential of EMDR as a brief intervention for low self-esteem and body image disturbances. The authors described a young female with a history of bulimia-like behaviour who, following completion of two EMDR sessions, showed significant improvements in scores on the Self-Esteem Rating Scale and the Body Image Avoidance Questionnaire. A case study by Halvgaard (Reference Halvgaard2015) examined whether EMDR could reduce symptoms associated with emotional eating. A 55-year-old woman with problems with emotional eating and feelings of loss of control over food underwent six weekly sessions of EMDR. Her treatment followed a specialised EMDR protocol, the adjusted Desensitization of Triggers and Urge Reprocessing (DeTUR™) protocol (Popky Reference Popky and Shapiro2005). She experienced an overall positive change in eating behaviour and affect regulation during triggering situations, results that were maintained at 3- and 6-month follow-up. Zaccagnino et al (Reference Zaccagnino, Cussino and Callerame2017) described the case of a 17-year-old in-patient with unremitting anorexia nervosa who received twice-weekly EMDR sessions for 6 months, with a focus on reprocessing relational traumas. At the end of treatment, the young woman's BMI had increased from 14 to 21.5 and she no longer met criteria for anorexia nervosa. Furthermore, she reported an increase in self-confidence, with results maintained at 12- and 24-month follow-up. Lastly, Yaşar et al (Reference Yaşar, Abamor and Usta2019) summarised the cases of two young girls with avoidant/restrictive food intake disorder as a consequence of traumatic events, who were treated with seven sessions of EMDR therapy combined with nine sessions of CBT. Both girls experienced significant reductions in associated symptoms of anxiety and depression and were subsequently able to eat a greater variety of foods.
In the randomised experimental trial by Bloomgarden & Calogero (Reference Bloomgarden and Calogero2008), 43 women receiving standard residential treatment for eating disorders (SRT) were compared with 43 women receiving SRT in addition to EMDR (SRT + EMDR) on measures of negative body image and other clinical outcomes. Those in the SRT + EMDR group received one or two EMDR sessions per week during their treatment stay, with a specific focus on body image problems. Those in the SRT + EMDR group reported less distress about negative body image memories and lower body dissatisfaction at post-treatment, 3-month and 12-month follow-up, compared with the SRT only group.
Although further research is still necessary, the preliminary findings of these studies imply a promising potential for the use of EMDR in treating eating disorders.
Substance misuse and addictions
Current interventions in addictions are limited by high relapse rates and low retention numbers. They are mostly based on self-control strategies that employ cognitive–behavioural approaches. These are not always appropriate or preferred by patients and there is a need to expand treatment strategies. EMDR offers various possibilities. It can be used to treat PTSD that is comorbid with addictions or underlying traumas associated with the onset of addiction, which is referred to as trauma-focused EMDR. There is also an adaptation of EMDR to process non-trauma memory representation of the addiction, referred to as the addiction-focused approach. These two approaches can be combined.
Markus & Hornsveld (Reference Markus and Hornsveld2017) performed a broad critical review of the literature on how EMDR is used in addictions. Their review comprised 18 studies of varying types, which are mostly lower-quality evidence, but include one RCT. They state that the current literature shows that EMDR's use in addictions is promising, but note that despite 20 years of research and development, addiction-focused EMDR approaches are still largely under-researched. In particular, they felt that EMDR may be useful in reducing the intensity of substance misuse-related imagery and craving.
Included in Markus & Hornsveld's review is Hase et al's (Reference Hase, Schallmayer and Sack2008) RCT, in which 34 individuals with alcohol dependence were randomised to treatment as usual (TAU) or treatment as usual plus EMDR (TAU + EMDR). EMDR treatment focused on the addiction memory, which includes preparatory behaviour, substance effects (substance use) and loss of control. The TAU + EMDR group showed a significant reduction in alcohol craving post-treatment and at 1-month follow-up, whereas the TAU group did not. A specialised EMDR protocol, the craving extinguished (CravEx) protocol, was used.
Meysami-Bonab et al (Reference Meysami-Bonab, Abolghasemi and Sheikhian2012) conducted an RCT on individuals with drug addictions attending an ‘addiction treatment camp’, in which 30 participants were randomised to either eight sessions of EMDR or no treatment. They had completed a period of detoxification before the interventions. They were assessed, using a questionnaire, for emotion regulation and emotion recognition. Those who received EMDR were found to have increased positive emotion regulation and emotion recognition in the post-test phase and their scores for negative emotion regulation were significantly improved. Their study was limited by lack of follow-up and the use of a single therapist and assessor. However, the finding of increased positive emotion regulation and recognition increases the possibility of recovery.
Sleep disturbances
EMDR is a recommended treatment in the best practice guide for the treatment of nightmare disorder in adults (Aurora Reference Aurora, Zak and Auerbach2010) commissioned by the American Academy of Sleep Medicine. This review of evidence recognises that it is based on two lower-level studies (Silver Reference Silver, Brooks and Obenchain1995; Raboni Reference Raboni, Tufik and Suchecki2006). It is thought that the efficacy of EMDR in nightmare disorder is based on its ability to induce the processing of disturbing memories and experiences by stimulating neural mechanisms that are similar to those activated during rapid eye movement (REM) sleep (Stickgold Reference Stickgold2008; Aurora Reference Aurora, Zak and Auerbach2010).
Psychosis
Although EMDR may not cure psychosis, it may have a role in ameliorating psychotic symptoms. Adams et al (Reference Adams, Ohlsen and Wood2020) performed a comprehensive systematic review of the use of EMDR in psychosis. They found six studies: one RCT, two case series, one case report and two pilot studies, one of which used an RCT design and the other an open trial with one arm. Their total sample comprised 236 adults, with individual study sample size ranging from 27 to 155. Participants had a range of psychotic disorders: schizophrenia, schizoaffective disorder, delusional disorders (including olfactory reference syndrome), bipolar disorder with psychotic features, and psychosis not otherwise specified. The number of EMDR sessions received ranged from one to ten. The authors found that the application of EMDR in psychosis was associated with reductions in delusional thinking and negative symptoms of psychosis, as well as improved social and general functioning, longer remission, fewer readmissions to hospital, reduction in use of mental health services and reduction in use of medications. These benefits were maintained at 10-year follow-up. There were mixed findings for the management of auditory hallucinations and paranoid thinking.
Conversely, in a study involving 40 individuals with schizophrenia, Kim et al (Reference Kim, Choi and Kim2010) found that EMDR was no more effective in reducing symptoms associated with schizophrenia, anxiety and depression than progressive muscle relaxation (PMR) therapy or treatment as usual. However, effect size for negative symptoms was large for the EMDR group compared with the control groups (ES = 0.60 for EMDR, ES = 0.39 for PMR and ES = 0.21 for treatment as usual).
Of note, a Japanese researcher (Kikuchi Reference Kikuchi2008) published the earliest peer-reviewed article detailing the application of EMDR therapy to schizophrenia. This work has not yet been published in English. Its model and concepts have borrowed much from how CBT is applied in schizophrenia. These are described by Miller (Reference Miller2015).
Trauma has been shown to be a significant predictor of psychosis (Read Reference Read, van Os and Morrison2005; Shevlin Reference Shevlin, Dorahy and Adamson2007), meaning that screening and treatment of trauma symptoms should be an important consideration in individuals with psychotic disorders. To this end, two studies have examined the safety and efficacy of using EMDR to treat PTSD in patients with psychosis. In a feasibility study, de Bont et al (Reference de Bont, Van Minnen and De Jongh2013) found that 7 of 10 individuals treated with either EMDR or prolonged exposure therapy no longer met the diagnostic criteria for PTSD at follow-up. No serious adverse events were reported and participants did not exhibit any worsening of delusions, hallucinations, general psychopathy or social functioning. However, participants were followed up for only 3 months, the sample was small, and the study focused on auditory hallucinations, not including other types of hallucination. The study was also limited by the lack of a control group and the use of clinical chart diagnosis to determine lifetime diagnosis. An RCT by van den Berg et al (Reference van den Berg, de Bont and van der Vleugel2015) also suggested that EMDR is safe and effective in treating PTSD in people with psychosis. They randomised 155 patients to receive either prolonged exposure therapy or EMDR or to a waiting list. Participants in both treatment conditions experienced greater reductions in PTSD symptoms than those on the waiting list. Importantly, no severe adverse events occurred as a result of the interventions. In their 12-month follow-up study, van den Berg et al (Reference van den Berg, de Bont and van der Vleugel2018) showed that positive effects were maintained for reductions in PTSD symptoms, depression and paranoid-referential thinking and for remission from schizophrenia in both treatment groups. The authors therefore concluded that their results suggested that trauma-focused therapies such as EMDR have long-term neutral to positive effects on symptoms of PTSD, depression and psychosis in people with psychotic disorders.
The specific ways in which EMDR was employed in the treatment processes described above were to target and process the traumatic memories that caused comorbid PTSD (van den Berg Reference van den Berg and van der Gaag2012; de Bont Reference de Bont, Van Minnen and De Jongh2013; Laugharne Reference Laugharne, Marshall and Laugharne2014; Adams Reference Adams, Ohlsen and Wood2020), to target and process hallucinations associated with negative beliefs about self and others (Kratzer Reference Kratzer, Heinz and Schennach2017) and to target life experiences that triggered olfactory reference syndrome (McGoldrick Reference McGoldrick, Begum and Brown2008).
Despite this exciting potential for the application of EMDR in psychosis, existing studies are limited by lower sample sizes and power, with their study designs making the overall quality of evidence low. Preliminary guidelines on the skilled use of EMDR in the management of psychosis have been published by a team of subject experts (van den Berg Reference van den Berg, van der Vleugel and Staring2013).
Somatoform disorders, including chronic pain syndromes
Medically unexplained symptoms
van Rood & de Roos (Reference van Rood and de Roos2009) carried out a systematic review of the use of EMDR in medically unexplained or functional syndromes. They felt this research area was still in its ‘infancy’ and more studies were needed; however, they uncovered 16 studies, including 1 RCT, 2 uncontrolled clinical studies, 7 case series and 6 case reports. The physical symptoms reported were chronic pain, phantom limb pain and psychogenic non-epileptic seizures. Others conditions included body dysmorphic disorder, myoclonic movement, olfactory reference syndrome, stress-related dermatological disorders and chronic fatigue syndrome. Of the 46 participants for whom comorbidity information was available, 14 (30%) had at least one comorbid disorder; 11 (24%) had PTSD, 9 (20%) had major depression and 2 had mixed anxiety and depression. The rationale for the use of EMDR was often not explicitly stated in the studies. It was thought that in most studies, EMDR was used because stressful or traumatic events were assumed to be indicated in the aetiology and maintenance of the medically unexplained symptoms (van Rood Reference van Rood and de Roos2009). EMDR was also used because particular medically unexplained symptoms appeared similar to those in PTSD but with symptoms displayed in specific sensory modalities. The number of sessions ranged from 1 to 72 and the duration of therapy ranged from 1 week to 18 months. After treatment with EMDR, not only did the intensity of physical symptoms reduce but psychological symptoms also decreased, with results maintained at follow-up.
Chronic pain syndromes, including phantom limb pain
Two systematic reviews have evaluated the current body of literature on the use of EMDR in treating chronic pain syndromes. Tesarz et al (Reference Tesarz, Leisner and Gerhardt2014) found two RCTs and multiple observational studies assessing phantom limb pain, headache, musculoskeletal pain and fibromyalgia. The two trials showed significant improvements in pain intensity following EMDR treatment, with high effect sizes. Effect sizes in the observational studies, however, varied considerably in measuring reductions in pain intensity and improvements in disability, depressive symptoms and anxiety. Follow-up assessments generally found improvements to be maintained over time. A more recent review by Tefft & Jordan (Reference Tefft and Jordan2016) included three RCTs and multiple uncontrolled clinical studies and case series. Most of these studies reported significant improvements on pain and psychological indices following treatment with EMDR. However, the authors cautioned that most of the evidence currently comes from case studies and that the included RCTs have limited applicability, as one provided only a single session of EMDR and the other focused on the management of acute pain in migraines. Of the chronic pain conditions studied, there appears to be the greatest amount of support for the use of EMDR in phantom limb pain (Wilensky Reference Wilensky2006; Schneider Reference Schneider, Hofmann and Rost2007, Reference Schneider, Hofmann and Rost2008; Russell Reference Russell2008; de Roos Reference de Roos, Veenstra and de Jongh2010). Indeed, Tefft & Jordan (Reference Tefft and Jordan2016) suggested that phantom limb pain appears to be particularly conducive to successful treatment with EMDR, with 92% of indviduals experiencing moderate to substantial improvement in pain severity along with improvement in anxiety, PTSD and depression. One additional RCT has been published since these reviews. Gerhardt et al (Reference Gerhardt, Leisner and Hartmann2016) randomised 40 participants with chronic, non-specific back pain who reported previous experiences of psychological trauma to either receive 10 sessions of pain-focused EMDR in addition to treatment as usual or treatment as usual alone. Comparisons of pain intensity and disability post-treatment between the groups suggested significant improvements in the EMDR group, with moderate to large effect sizes. Furthermore, almost 50% of participants in the EMDR group rated their symptoms as either ‘improved’ or ‘very much improved’, compared with none in the control group.
Summary
Although most studies thus far have found EMDR to be a safe and effective treatment for a variety of somatoform and chronic pain syndromes, the majority of the literature has been case studies and so there is currently insufficient evidence for definite treatment recommendations.
Summary and conclusions
Apart from its approved use for treating PTSD, EMDR has been shown to be useful in the treatment of a variety of affective and non-affective conditions. Specifically, this review has presented high-quality evidence supporting the use of EMDR in the management of panic disorder, specific phobia, OCD and major depressive disorder. It has been shown to be potentially useful in the management of bipolar affective disorder, although more evidence is needed. Moreover, its usefulness is not limited to these conditions. Early evidence points to the potential usefulness of EMDR in the management of eating disorders and substance misuse. EMDR is recommended, by subject experts, for the treatment of dissociative identity disorder and nightmare disorder. It has also been found to be helpful for individuals suffering from complex disorders such as somatoform disorders and chronic pain syndromes. The mechanisms by which it helps in these latter conditions are less clear, but they appear to require an increased number of sessions and a longer duration of treatment compared with PTSD.
Although EMDR used to be considered unsuitable for psychosis, evolving evidence supports its safe use in some cases. This use of EMDR is based on several concepts. The adverse early childhood experiences of many people with psychosis constitute unresolved trauma. This trauma is often an important aspect of their illness, including triggers for the onset of psychosis, the resolution of which improves symptoms. Furthermore, the events of having a psychotic breakdown and/or being treated in mental health services are potentially traumatic in themselves and may in some cases lead to post-traumatic stress symptoms. It is now acknowledged that psychoses and PTSD may occur comorbidly, influencing one another and leading to ongoing traumatisation (Marconi Reference Marconi and Polidoro2018).
The evidence supporting the use of EMDR in treating PTSD is incontrovertible, especially in adults, but this review highlights areas where further research is needed. Furthermore, there is a sense of urgency, given the ubiquity of mental illnesses such as anxiety and depressive disorders and the complexity of disorders such as eating, substance use and somatoform disorders. The outcomes of studies presented in this review are indeed encouraging. Hence, there is promise that treatment guidelines may be expanded and it is our hope that this article enlightens clinicians to consider these possibilities and advocate for services that can deliver these interventions for the good and well-being of patients.
Acknowledgements
We are grateful the Francine Shapiro (Electronic) Library of the EMDR International Association; the Mental Health Library at Parkwood Institute, St Joseph's Healthcare London, Ontario; and the library services of the University of Western Ontario, Canada. We thank Alexandra Richman, EMDR Approved Trainer and Approved Consultant (UK), for her practical support, and consultant psychiatrist Dr Carol McDaniel for her helpful comments on our draft paper.
Author contributions
All co-authors made equal contributions to the conception and design of the work and the acquisition, analysis or interpretation of data. All were also involved in drafting the work and revising it critically for important intellectual content. All co-authors gave final approval of the version to be published and agree to be accountable for all aspects of the work.
Funding
This research received no specific grant from any funding agency, commercial or not-for-profit sectors.
Declaration of interest
I.U. is a member of the BJPsych Advances editorial board and did not take part in the review or decision-making process of this article.
MCQs
1 Indications for which EMDR has been used successfully include:
a depressive disorders
b chronic pain
c panic disorder
d psychosis
e all of the above.
2 Concerning the use of EMDR for anxiety disorders, meta-analysis found that:
a EMDR reduces only anxiety symptoms
b EMDR reduces only anxiety and panic symptoms
c EMDR reduces only phobic symptoms
d EMDR reduces only phobic and somatic symptoms
e EMDR reduces anxiety, panic, phobic and somatic symptoms.
3 Studies on the use of EMDR in depression suggest that:
a EMDR may be used as a stand-alone treatment for depression
b EMDR may be used in addition to other psychotherapies
c EMDR may be used in addition to medication
d EMDR may target negative memories associated with the development of depression
e all of the above.
4 As regards the rationale for the use of EMDR in the treatment of psychosis:
a EMDR targets traumatic memories that are associated with comorbid PTSD
b EMDR targets hallucinatory experiences that are associated with negative beliefs about self and others
c EMDR targets negative life experiences that trigger psychosis
d EMDR targets traumatic memories of having a psychotic breakdown and hospital admission
e all of the above.
5 Which of the following statements is false:
a EMDR is included in a best practice guide for treating nightmares
b practitioners need to be specially trained to use EDMR to treat patients with dissociative identitity disorder
c a randomised controlled trial has not shown EMDR to be comparable to CBT in treating OCD
d with respect to chronic pain, the greatest amount of evidence exists to support EDMR's use in phantom limb pain
e research into EMDR as a treatment for eating disorders is currently mostly limited to case studies.
MCQ answers
1 e 2 e 3 e 4 e 5 c
eLetters
No eLetters have been published for this article.