Utilising a microscope for otological surgery offers a plethora of advantages, such as ambidextrous hand mobility and stereopsis.Reference Mudry1 Endoscopic ear surgery, on the other hand, offers a more transparent view of the middle-ear cavity that is not limited by the line-of-sight view, with the disadvantages of single-handed surgery and two-dimensional views.Reference Baazil, Dobbe, van Spronsen, Ebbens, Dikkers and Streekstra2,Reference Guneri and Cakir3 An article in this month's issue of The Journal of Laryngology & Otology sought to compare microscopic and endoscopic stapes surgery.Reference Hajiioannou, Gkrinia, Tzimkas-Dakis, Palla, Brotis and Korais4 Thirteen studies were included in their meta-analysis. Although both techniques resulted in comparable outcomes concerning success rates (as evaluated by air–bone gap improvement), post-operative pain and dysgeusia favoured the endoscopic approach. The authors hypothesise that the improved visualisation of the surgical field provided by the endoscope enables less bony auditory canal drilling, and, consequently, less post-operative pain, as well as limited manipulation of the chorda tympani, leading to better rates regarding post-operative dysgeusia. However, the authors point out that like any other newly introduced technology, this innovative approach has a learning curve for those not acquainted with endoscopic otology.Reference Narendrakumar5 Their findings are comparable to previous studies which have also concluded that endoscopic stapes surgery has similar surgical and functional advantages as compared with microscopic surgery.Reference Pauna, Pereira, Monsanto, Amaral and Hyppolito6
A study by Flynn et al. in this month's issue seeks to address whether patients are presenting later and with more advanced head and neck cancer following the coronavirus disease 2019 pandemic.Reference Flynn, Maqsood, Maseland, Montgomery and Douglas7 This retrospective cohort study compared all presentations of head and neck cancer between June and October of 2019 with the same period following the peak of the pandemic in 2020 in West Scotland, a region populated by 2.5 million people. A total of 528 patients met the study inclusion criteria. Compared with 2019, patients in 2020 were more likely to present with a higher cancer stage (p = 0.002) and have a longer preceding symptom duration (p < 0.001), and were more likely to have an emergency hospital admission attributed to head and neck cancer complications or sequelae (p = 0.017). Further work is required to assess whether these findings are temporary or longer lasting (e.g. as a result of patient reluctance to seek medical attention, or difficulties in accessing primary care).Reference Bhamra, Gorman, Arnold, Rajah, Jolly and Nieto8
Finally, the molecular correlates of obstructive sleep apnoea were studied by Lin et al., who found that patients with obstructive sleep apnoea demonstrated more severe inflammation, increased airway remodelling, and increased protein and messenger RNA expression of pro-inflammatory and pro-fibrotic cytokines compared with control participants.Reference Lin, Wang, Chiu, Sun, Lin and Tzeng9 It is hypothesised that airway inflammation and remodelling may alter tissue compliance, which could adversely affect upper airway collapsibility.