Jostedalsbreen in western Norway is the mainland Europe's largest ice cap and a complex system of more than 80 glaciers. While observational records indicate a significant sensitivity to climate fluctuations, knowledge about ice-cap wide spatiotemporal mass changes and their drivers remain sparse. Here, we quantify the surface mass balance (SMB) of Jostedalsbreen from 1960 to 2020 using a temperature-index model within a Bayesian framework. We assimilate seasonal glaciological SMB to constrain accumulation and ablation, and geodetic mass balance to adjust model parameters for each glacier individually. Overall, we find that Jostedalsbreen has experienced a small mass loss of −0.07 m w.e. a−1 (−0.21 to +0.08 m w.e. a−1), but with substantial spatiotemporal variability. Our results suggest that winter SMB variations were the main control on annual SMB between 1960 and 2000, while increasingly negative summer SMB is responsible for substantial mass losses after 2000. Spatial variations in SMB between glaciers or regions of the ice cap are likely associated with local topography and its effect on orographic precipitation. We advocate for models to leverage the growing availability of observational resources to improve SMB predictions. We demonstrate an approach that incorporates complementary datasets, while addressing their inherent uncertainties, to constrain models and provide robust estimates of spatiotemporal SMB and associated uncertainties.