Hostname: page-component-6587cd75c8-67gbf Total loading time: 0 Render date: 2025-04-24T03:55:49.029Z Has data issue: false hasContentIssue false
  • English
  • Français

A case series of interventions and outcomes in patients with laryngeal squamous cell cancer

Published online by Cambridge University Press:  25 April 2024

Richard Townsley ,
Jiak Ying Tan ,
Elbert Edy ,
Alison Lim Open the ORCID record for Alison Lim [Opens in a new window]  and
Jeremy McMahon
Richard Townsley
Affiliation:
Department of Otorhinolaryngology, University Hospital Crosshouse, Kilmarnock, Scotland, UK
Jiak Ying Tan
Affiliation:
Department of Otorhinolaryngology, Glasgow Royal Infirmary, Glasgow, Scotland, UK
Elbert Edy
Affiliation:
Department of Otorhinolaryngology, University of Glasgow, Glasgow, Scotland, UK
Alison Lim*
Affiliation:
Department of Otorhinolaryngology, Queen Elizabeth University Hospital, Glasgow, Scotland, UK
Jeremy McMahon
Affiliation:
Department of Otorhinolaryngology, Queen Elizabeth University Hospital, Glasgow, Scotland, UK Department of Maxillofacial Surgery, Queen Elizabeth University Hospital, Glasgow, Scotland, UK
*
Corresponding author: Alison Lim; Email: [email protected]
Get access Rights & Permissions [Opens in a new window]

Abstract

Objective

The larynx is the second most prevalent subsite for head and neck cancer. Over half of head and neck cancer patients present with advanced disease. We report our regional practices for palliative intent laryngeal squamous cell cancer (SCC).

Methods

Retrospective analysis of patients with laryngeal SCC treated with palliative intent, discussed at the regional head and neck multidisciplinary team meeting from July 2010 to June 2016.

Results

A total of 65 patients were included, of whom 45 per cent had potentially curable disease but were not fit for curative treatment. Nine patients (14 per cent) underwent tracheostomy, with mean survival and hospital stay of 278 and 48 days, respectively. Four patients (6 per cent) underwent debulking surgery with mean survival and hospital stay of 214 and 1 days, respectively.

Conclusion

All palliative treatment measures offered to patients can have an impact on survival and quality of life. Patients should be at the centre of the decision-making process and counselled on the potential impact of interventions.

Keywords

head and neck neoplasmspalliative caretracheostomylaryngeal neoplasmsquality of life
Type
Main Article
Information
The Journal of Laryngology & Otology , Volume 138 , Issue 9 , September 2024 , pp. 961 - 964
Copyright
Copyright © The Author(s), 2024. Published by Cambridge University Press on behalf of J.L.O. (1984) LIMITED

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

Article purchase

Temporarily unavailable

Footnotes

Alison Lim takes responsibility for the integrity of the content of the paper

References

Schenker, Y, Arnold, RM, Bauer, JE. An enhanced role for palliative care in the multidisciplinary approach to high-risk head and neck cancer. Cancer 2015;122:340–3CrossRefGoogle ScholarPubMed
Doobaree, IU, Landis, SH, Linklater, KM, El-Hariry, I, Moller, H, Tyczynski, J. Head and neck cancer in south east England between 1995–1999 and 2000–2004: an estimation of incidence and distribution by site, stage and histological type. Oral Oncol 2008;45:809–14CrossRefGoogle Scholar
Begbie, FD, Douglas, CM, Finlay, F, Montgomery, J. Palliative intent treatment for head and neck cancer: an analysis of practice and outcomes. J Laryngol Otol 2019;133:313–17CrossRefGoogle ScholarPubMed
Timon, C, Reilly, K. Head and neck mucosal squamous cell carcinoma: results of palliative management. J Laryngol Otol 2006;120:389–92CrossRefGoogle ScholarPubMed
Nilsen, ML, Johnson, JT. Potential for low-value palliative care of patients with recurrent head and neck cancer. Lancet Oncol 2017;18:e284–9CrossRefGoogle ScholarPubMed
Berrino, F, Gatta, G. Variation in survival of patients with head and neck cancer in Europe by site of origin of the tumours. EUROCARE Working Group. Eur J Cancer 1998;34:2154–61CrossRefGoogle ScholarPubMed
Kowalski, LP, Carvalho, AL. Natural history of untreated head and neck cancer. Eur J Cancer 2000;36:1032–7CrossRefGoogle ScholarPubMed
McMahon, JD, Robertson, GA, Liew, C, McManners, J, Mackenzie, FR, Hislop, WS et al. Oral and oropharyngeal cancer in the West of Scotland – long-term outcome data of a prospective audit 1999–2001. Br J Oral Maxillofac Surg 2011;49:92–8CrossRefGoogle ScholarPubMed
Pracy, P, Loughran, S, Good, J, Parmar, S, Goranova, R. Hypopharyngeal cancer: United Kingdom National Multidisciplinary Guidelines. J Laryngol Otol 2016;130(suppl 2):104–10CrossRefGoogle ScholarPubMed
Ledeboer, QCP, Van der Schroeff, MP, Pruyn, JFA, de Boer, MF, de Jong RJ, Baatenburg, van der Welden, LA. Survival of patients with palliative head and neck cancer. Head Neck 2011;33:1021–6CrossRefGoogle ScholarPubMed
Koo, MM, Swann, R, McPhail, S, Abel, GA, Elliss-Brookes, L, Rubin, GP et al. Presenting symptoms of cancer and stage at diagnosis: evidence from a cross-sectional, population-based study. Lancet Oncol 2020;21:73–9CrossRefGoogle ScholarPubMed
Duncan, W, MacDougall, RH, Kerr, GR, Downing, D. Adverse effect of treatment gaps in the outcome of radiotherapy for laryngeal cancer. Radiother Oncol 1996;41(3):203–7CrossRefGoogle ScholarPubMed
Nikolaou, AC, Markou, CD, Petridis, Daniilidis IC. Second primary neoplasms in patients with laryngeal carcinoma. Laryngoscope 2000;110:58–64CrossRefGoogle ScholarPubMed
Paleri, V, Stafford, FW, Sammut, MS. Laser debulking in malignant upper airway obstruction. Head Neck 2005;27:296–301CrossRefGoogle ScholarPubMed
Chan, JY, To, VS, Wong, ST, Wei, WI. Quality of dying in head and neck cancer patients: the role of surgical palliation. Eur Arch Otorhinolaryngol 2013;270:681–8CrossRefGoogle Scholar