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Live birth following a single oocyte fertilized with ICSI and embryo transfer on day 2: a case report

Published online by Cambridge University Press:  03 September 2020

Romualdo Sciorio Open the ORCID record for Romualdo Sciorio [Opens in a new window] ,
Elisavet Angelaki  and
Naser Al-Azemi
Romualdo Sciorio*
Affiliation:
Edinburgh Assisted Conception Programme, EFREC, Royal Infirmary of Edinburgh, Edinburgh, Scotland, UK Reproductive Medicine & IVF Unit, Royale Hayat Hospital, Kuwait City, Kuwait
Elisavet Angelaki
Affiliation:
Reproductive Medicine & IVF Unit, Royale Hayat Hospital, Kuwait City, Kuwait
Naser Al-Azemi
Affiliation:
Reproductive Medicine & IVF Unit, Royale Hayat Hospital, Kuwait City, Kuwait
*
Author for correspondence: Romualdo Sciorio. Edinburgh Assisted Conception Programme, EFREC, Royal Infirmary of Edinburgh, 51 Little France Crescent, Old Dalkeith Road, Edinburgh, Scotland, EH16 4SA, UK. E-mail: [email protected]
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Summary

In this report, we present a case of a couple who obtained a live birth with a single oocyte fertilized by intracytoplasmic sperm injection. The oocyte was collected at 36 h post trigger and was found to be at metaphase II when sperm injection was performed. At 18 h post injection, the oocyte was found to be fertilized with two clear pronuclei. The embryo divided and generated a four-cell embryo on day 2, which was replaced to the uterine cavity. Pregnancy test gave a positive β-human chorionic gonadotropin result, the scan performed at 7 weeks, revealed the presence of one amniotic sac with fetal heartbeat. Healthy live birth was obtained after 39 weeks of gestation.

Keywords

Cumulus–oocyte complex (COC)Fertilization and embryo cultureIn vitro fertilization (IVF)Intracytoplasmic sperm injectionLive birth
Type
Short Communication
Information
Zygote , Volume 28 , Issue 6 , December 2020 , pp. 516 - 518
Copyright
© The Author(s), 2020. Published by Cambridge University Press

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References

Bourne, H, Edgar, DH and Baker, HWG (2004). Sperm Preparation Techniques. In: Gardner, DK, Weissman, A, Howles, CM and Shoham, Z (eds). Textbook of Assisted Reproductive Techniques 2004: Laboratory and Clinical Perspectives 2nd edn. USA: Informa Healthcare, pp. 79–91.Google Scholar
Cobo, A, García-Velasco, J, Domingo, J, Pellicer, A and Remohí, J (2018). Elective and onco-fertility preservation: factors related to IVF outcomes. Hum Reprod 33, 2222–31.CrossRefGoogle ScholarPubMed
De Geyter, C, Calhaz-Jorge, C, Kupka, MS, Wyns, C, Mocanu, E, Motrenko, T, Scaravelli, G, Smeenk, J, Vidakovic, S and Goossens, V (2018). European IVF-monitoring Consortium (EIM) for the European Society of Human Reproduction and Embryology (ESHRE). ART in Europe, 2014: results generated from European registries by ESHRE: The European IVF-monitoring Consortium (EIM) for the European Society of Human Reproduction and Embryology (ESHRE). Hum Reprod 33, 1586–601.CrossRefGoogle Scholar
Esteves, SC, Carvalho, JF, Bento, FC and Santos, J (2019a). A novel predicative model to estimate the number of mature oocytes required for obtaining al least one euploid blastocyst for transfer in couples undergoing in vitro fertilization/intracytoplasmic sperm injection: the ART calculator. Front Endocrinol (Lausanne) 10, 99.CrossRefGoogle Scholar
Esteves, SC, Carvalho, JF, Martinhago, CD, Melo, AA, Bento, FC, Humaidan, P and Alviggi, C (2019b). POSEIDON (Patient-Oriented Strategies Encompassing IndividualizeD Oocyte Number) Group. Estimation of age-dependent decrease in blastocyst euploidy by next generation sequencing: development of a novel prediction model. Panminerva Med 61, 3–10.CrossRefGoogle ScholarPubMed
Esteves, SC, Yarali, H, Ubaldi, FM, Carvalho, JF, Bento, FC, Vaiarelli, A, Cimadomo, D, Özbek, İY, Polat, M, Bozdag, G, Rienzi, L and Alviggi, C (2020). Validation of ART calculator for predicting the number of metaphase II oocytes required for obtaining at least one euploid blastocyst for transfer in couples undergoing in vitro fertilization/intracytoplasmic sperm injection. Front Endocrinol (Lausanne) 10, 917.CrossRefGoogle ScholarPubMed
Gardner, DK (2016). The impact of physiological oxygen during culture, and vitrification for cryopreservation, on the outcome of extended culture in human IVF. Reprod Biomed Online 32, 137–41.CrossRefGoogle ScholarPubMed
Gardner, DK and Schoolcraft, WB (1999). Culture and transfer of human blastocysts. Curr Opin Obstet Gynecol 11, 307–11.CrossRefGoogle ScholarPubMed
Hu, Y, Maxson, WS, Hoffman, DI, Ory, SJ, Eager, S, Dupre, J and Lu, C (1998). Maximizing pregnancy rates and limiting higher-order multiple conceptions by determining the optimal number of embryos to transfer based on quality. Fertil Steril 69, 650–7.CrossRefGoogle ScholarPubMed
Human Fertilisation and Embryology Authority (2018). Fertility treatment 2014–2016. Trends and figures. Available at https://www.hfea.gov.uk/media/2563/hfea-fertility-trends-and-figures-2017-v2.pdf (accessed 1 March 2018).Google Scholar
Niederberger, C, Pellicer, A, Cohen, J, Gardner, DK, Palermo, GD, O’Neill, CL, Chow, S, Rosenwaks, Z, Cobo, A, Swain, JE, et al. (2018). Forty years of IVF. Fertil Steril 110, 185–324.e5.CrossRefGoogle Scholar
Palermo, G, Joris, H, Devroey, P and Van Steirteghem, AC (1992). Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte. Lancet 340, 17–8.CrossRefGoogle ScholarPubMed
Palomba, S, Santagni, S and La Sala, GB (2015). Progesterone administration for luteal phase deficiency in human reproduction: an old or new issue? J Ovarian Res 8, 77–92.CrossRefGoogle ScholarPubMed
Sciorio, R and Smith, GD (2019). Embryo culture at a reduced oxygen concentration of 5%: a mini review. Zygote 23, 1–7.Google Scholar
Steptoe, PC and Edwards, RG (1978). Birth after the reimplantation of a human embryo. Lancet 2, 366.CrossRefGoogle ScholarPubMed
Thoma, ME, McLain, AC, Louis, JF, King, RB, Trumble, AC, Sundaram, R and Buck Louis, GM (2013). The prevalence of infertility in the United States as estimated by the current duration approach and a traditional constructed approach. Fertil Steril 99, 1324–31.CrossRefGoogle Scholar
Ubaldi, FM, Cimadomo, D, Vaiarelli, A, Fabozzi, G, Venturella, R, Maggiulli, R, Mazzilli, R, Ferrero, S, Palagiano, A and Rienzi, L (2019). Advanced maternal age in IVF: still a challenge? The present and the future of its treatment. Front Endocrinol (Lausanne) 10, 94.CrossRefGoogle Scholar
Vaiarelli, A, Cimadomo, D, Ubaldi, N, Rienzi, L and Ubaldi, FM (2018). What is new in the management of poor ovarian response in IVF? Curr Opin Obstet Gynecol 30, 155–62.Google ScholarPubMed
Voronina, E and Wessel, G (2003). The regulation of oocyte maturation. Curr Top Dev Biol 58, 53–110.CrossRefGoogle ScholarPubMed
Zhao, Y, Brezina, P, Hsu, CC, Garcia, J, Brinsden, PR and Wallach, E (2011). In vitro fertilization: four decades of reflections and promises. Biochim Biophys Acta 1810, 843–52.CrossRefGoogle ScholarPubMed