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Meiotic cycle checkpoints in mammalian oocytes

Published online by Cambridge University Press:  26 September 2008

Josef Fulka Jr ,
Judy Bradshaw  and
Robert Moor
Josef Fulka Jr
Affiliation:
Deparment of Development and Singnalling, The Babraham Institute, Cambridge, CB2 4AT, UK
Judy Bradshaw
Affiliation:
Deparment of Development and Singnalling, The Babraham Institute, Cambridge, CB2 4AT, UK
Robert Moor
Affiliation:
Deparment of Development and Singnalling, The Babraham Institute, Cambridge, CB2 4AT, UK
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Extract

Recent Spectacular achievements have enabled the identification of key molecules responsible for mitotic cell cycle progression through the stages of G1, the gap before DNA replication; S, the phase of DNA synthesis; G2, the gap before chromosome segregation; and M, mitosis itself. The last stage has been most intensively studied, where MPE, maturation promotion factor, has been found responsible for the nuclear events associated with chromosomal segregation and the prodcution of two identical daughter cells (see Murray & Hunt, 1993).

Type
Article
Information
Zygote , Volume 2 , Issue 4 , November 1994 , pp. 351 - 354
Copyright
Copyright © Cambridge University Press 1994

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