Hostname: page-component-78c5997874-ndw9j Total loading time: 0 Render date: 2024-11-05T11:44:57.675Z Has data issue: false hasContentIssue false
  • English
  • Français

The role, importance and toxicity of arsenic in poultry nutrition

Published online by Cambridge University Press:  20 August 2019

M. ŽIVKOV BALOŠ ,
S. JAKŠIĆ  and
D. LJUBOJEVIĆ PELIĆ Open the ORCID record for D. LJUBOJEVIĆ PELIĆ [Opens in a new window]
M. ŽIVKOV BALOŠ
Affiliation:
Scientific Veterinary Institute “Novi Sad”, Rumenački put 20, 21000 Novi Sad, Serbia
S. JAKŠIĆ
Affiliation:
Scientific Veterinary Institute “Novi Sad”, Rumenački put 20, 21000 Novi Sad, Serbia
D. LJUBOJEVIĆ PELIĆ*
Affiliation:
Scientific Veterinary Institute “Novi Sad”, Rumenački put 20, 21000 Novi Sad, Serbia
*
Corresponding author: [email protected], [email protected]
Get access

Abstract

Arsenic (As) is highly toxic element, even at very low concentrations in feed and drinking water. Its physiological role in poultry is well established, as it is essential for the synthesis of methionine metabolites including cysteine, even though it is a teratogenic and carcinogenic element. Paradoxically, recent studies have uncovered its nutritional value. The recommended amounts of As in poultry feed are between 0.012 and 0.050 mg/kg. Water is the primary route for the transfer of As and exposure of animals to its toxic effects. The available data on the impact of water contamination on the deposition of As in broiler tissues are rather scarce. The amount of As was 0.006-0.015 mg/kg in breast meat, 0.007-0.017 mg/kg in drumstick meat, 0.001-0.014 mg/kg in liver and 0.008-0.016 mg/kg in testicles of broilers at the end of a 42 day experiment after exposure to naturally contaminated drinking water. The toxic dose of As for poultry is between 40 and 50 mg/kg of poultry feed whereas the amount of 40 mg/kg leads to decreased egg production and the amount of 50 mg/kg leads to decreased feed consumption. Symptoms of chronic As exposure differ among individuals, populations and geographic regions, which suggests that there is no universal definition of symptoms associated with chronic As poisoning. Moreover, some individuals can tolerate high As, that is, levels that can be fatal for others. In wild birds, the content of As was the highest in meat of march hens (0.063 mg/kg), seagull muscle tissue (0.058 mg/kg), in meat from swans (0.022 mg/kg) and the white-tailed eagle (0.022 mg/kg). In this review, the essential role and toxicity of As in poultry nutrition is addressed with particular emphasis on its importance as a contaminant of poultry feed and products.

Keywords

Asessentialitytoxicitypoultrynutrition
Type
Review
Information
World's Poultry Science Journal , Volume 75 , Issue 3 , September 2019 , pp. 375 - 386
Copyright
Copyright © World's Poultry Science Association 2019 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

ADAMS, P., VAN DER FELS-KLERX, H.J. and DE JONG, J. (2017) As, lead, cadmium and mercury in animal feed and feed materials. Trend analysis of monitoring results collected in the Netherlands. RIKILT Wageningen University and Research, University of Wageningen.Google Scholar
BEAVER, L.M., TRUONG, L., BARTON, C.L., CHASE, T.T., GONNERMAN, G.D., WONG, C.P., TANGUAY, R.L. and HO, E. (2017) Combinatorial effects of zinc deficiency and As exposure on zebrafish (Danio rerio) development. PloS ONE 12(8): e0183831.Google Scholar
BISWAS, U., SARKAR, S., BHOWMIK, M.K., SAMANTA, A.K. and BISWAS, S. (2000) Chronic toxicity of As in goats: clinicobiochemical changes, phatomorphology and tissue residues. Small Ruminants Research 38: 229-235.Google Scholar
CHATTOPADHYAY, S., DEB, B. and MAITI, S. (2012) Hepatoprotective role of vitamin B (12) and folic acid in As intoxicated rats. Drug and Chemical Toxicology 35 (1): 81-88.Google Scholar
CHIOU, W.S., CHEN, K.L. and YU, B. (1997) Effect of roxarsone on performance, toxicity, tissue accumulation and residues of eggs and excreta in laying hens. Journal of the Science of Food and Agriculture 74: 229-236.Google Scholar
COHEN, S.M., ARNOLD, L.L., ELDAN, M., LEWIS, A.S. and BECK, B.D. (2006) Methylated Asals: The implications of metabolism and carcinogenicity studies in rodents to human risk assessment. Critical Reviews in Toxicology 36: 99-133.Google Scholar
DABEKA, R.W., MCKENZIE, A.D., LACROIX, G.M., CLEROUX, C., BOWE, S. and GRAHAM, R.A. (1993) Survey of As in total diet food composites and estimation of the dietary intake of As by Canadian adults and children. Journal of Association of Official Analytical Chemists International 76: 14-25.Google Scholar
D'ANGELO, E., ZEIGLER, G., GLENN BECK, E., GROVE, J. and SIKORA, F. (2012) As species in broiler (Gallus gallus domesticus) litter, soils, maize (Zea mays L.), and groundwater from litter-amended fields. Science of Total Environment 438: 286-292.Google Scholar
DESESSO, J.M. (2001) Teratogen update: inorganic As. Teratology 63: 170-173.Google Scholar
DESESSO, J.M., JACOBSON, K.F., SCIALLI, A.R., FARR, C.H. and HOLSON, J.F. (1998) An assessment of the developmental toxicity of inorganic As. Reproductive Toxicology 12 (4): 385-433.Google Scholar
DESHENG, Q. and NIYA, Z. (2006) Effect of arsanilic acid on performance and residual of As in tissue of Japanese laying quail. Poultry Science 85: 2097-2100.Google Scholar
EFSA (2005) Opinion of the Scientific Panel on Contaminants in the Food Chain on a request from the Commission related to As as undesirable substance in animal feed. EFSA Journal 180: 1-35.Google Scholar
EISLER, R. (1988) As hazards to fish, wildlife, and invertebrates: a synoptic review. Contaminat Hazard Reviews U.S. Fish and Wildlife Service, Biological Report 85 (1.12).Google Scholar
GOLUB, M.S., MACINTOSH, M.S. and BAUMRIND, N. (1998) Developmental and reproductive toxicity of inorganic As: animal studies and human concerns. Journal of Toxicology and Environmental Health, Part B 1 (3): 199-241.Google Scholar
GRESS, J., DA SILVA, E.B., DE OLIVIERA, L.M., ZHAO, D., ANDERSON, G., HEARD, D., STUCHAL, L.D. and MA, L.Q. (2016) Potential As exposure in 25 species of zoo animals living in CCA-wood enclosures. Science of the Total Environment 551-552: 614-621.Google Scholar
HANSEN, H.R., RAAB, A., FRANCESCONI, K.A. and FELDMAN, J. (2003) Metabolism of As by sheep chronically exposed to arsenosugars as a normal part of their diet. 1. Quantitative intake, uptake, and excretion. Environmental Science and Technology 37: 845-851.Google Scholar
HERBEL, M.J., BLUM, S.E., HOEFT, S.E., COHEN, S.M., ARNOLD, L.L., LISAK, J., STOLZ, J.F. and OREMLAND, R.S. (2002) Dissimilatory arsenate reductase activity and arsenate-respiring bacteria in bovine rumen fluid, hamster feces, and termite hindgut. FEMS Microbiology Ecology 41: 59-67.Google Scholar
HUNDER, G., SCHAPER, J., ADEMUYIWA, O. and ELSENHANS, B. (1999) Species differences in As-mediated real copper accumulation: a comparison between rats, rats and guinea pigs. Human and Experimental Toxicology 18: 699-705.Google Scholar
JONES, F.T. (2007) A Broad View of As. Invited review. Poultry Science 86: 2-14.Google Scholar
KADIRVEL, R., SUNDARAM, K., MANI, S., SAMUEL, S., ELANGO, N. and PANNEERSELVAM, C. (2007) Supplementation of ascorbic acid and alpha-tocopherol prevents As-induced protein oxidation and DNA damage induced by As in rats. Human and Experimental Toxicology 26 (12): 939-946.Google Scholar
LI, Y. and CHEN, T. (2005) Concentrations of additive As in Beijing pig feeds and the residues in pig manure. Resources, Conservation and Recycling 45: 356-367.Google Scholar
MANDAL, P. (2017) An insight of environmental contamination of As on animal health. Emerging Contaminants 3: 17-22.Google Scholar
MANDAL, B.K. and SUZUKI, K.T. (2002) As round the world: a review. Talanta 58: 201-235.Google Scholar
MIHALJEV, Ž., ŽIVKOV BALOŠ, M., KAPETANOV, M. and JAKŠIĆ, S. (2013) Determination of toxic elements in wild birds from the area of Vojvodina. Proceedings of 10th International Symposium Modern Trends in Livestock Production, Belgrade, pp. 1196-1203.Google Scholar
MITCHELL, E., FRISBE, S. and SARKAR, B. (2011) Exposure to multiple metals from groundwater-a global crisis: Geology, climate change, health effects, testing and migration. Metallomics 3: 874-908.Google Scholar
NATIONAL ACADEMY OF SCIENCES (1977) As. National Academy Press, Washington D.C..Google Scholar
NIELSEN, F.H. (1998) Ultratrace elements in nutrition: current knowledge and speculation. Journal of Trace Elements in Experimental Medicine 11: 251-274.Google Scholar
NATIONAL RESEARCH COUNCIL (2005) Mineral tolerance of animals. Second revised edition, National Academy Press, Washington D.C.Google Scholar
PÈTURSDÓTTIR, Á.H.E., JÖRUNDSÓTTIR, H.Ó. and GUNNLAUGSDÓTTIR, H. (2010) Food safety and added value of Icelandic fishmeal – determination of toxic and non-toxic As species in fish meal. Skýrsluágrip Matís ohf, Icelandic Food and Biotech R and D,Google Scholar
PULS, R. (1990) Mineral levels in animal health. Diagnostic data. Sherpa International, Clearbrook, British Columbia.Google Scholar
RANA, S.V.S. (2007) Protective effect of ascorbic acid against oxidative stress induced by inorganic As in liver and kidney of rat. Indian Journal of Experimental Biology 45: 371-375.Google Scholar
ROY, P. and SAHA, A. (2002) Metabolism and toxicity of As: A human carcinogen. Current Science 82: 38-45.Google Scholar
RUTHERFORD, D.W., BEDNAR, A.J., GARBARINO, J.R., NEEDHAM, R., STAVER, K.W. and WERSHAW, A.J. (2003) Environmental fate of roxarsone in poultry litter. Part II. Mobility of As in soils amended with poultry litter. Environmental Science and Technology 37: 1515-1520.Google Scholar
SCHOEN, A.B., BECK, B., SHARMA, R. and DUBE, E. (2004) As toxicity at low doses: Epidemiological and mode of action considerations. Toxicology and Applied Pharmacology 198: 253-267.Google Scholar
SHAH, A.Q., KAZI, T.G., ARAIN, M.B., JAMALI, M.K., AFRIDI, H.I., JALBANI, N., ABBAS, G. and BAIG, J.A. (2009) Comparison of electro thermal and hydride generation atomic absorption spectrometry for the determination of total As in broiler chicken. Food Chemistry 113: 1351-1355.Google Scholar
SHARPE, M. (2003) Deadly waters run deep: The global As crisis. Journal of Environmental Monitoring 5: 81-85.Google Scholar
SINGH, S. and RANA, S.V. (2007) Amelioration of As by L-Ascorbic acid in laboratory rats. Journal of Environmental Biology 28 (2): 377-384.Google Scholar
TAO, S.S. and BOLGER, P.M. (1999) Dietary As intake in the United States. FDA Total diet study. Food Additives and Contaminants 16: 465-472.Google Scholar
VENTURA-LIMA, J., REIS BOGO, M. and MONSERRAT, J.M. (2011) As toxicity in mammals and aquatic animals: A comparative biochemical approach. Ecotoxicology and Environmental Safety 74: 211-218.Google Scholar
VODELA, J.K., LENZ, S.D., RENDEN, A.J., MCELHENNEY, W.H. and KEMPPAINEN, B.W. (1997) Drinking water contaminants (As, Cd, Pb, Benzene and Trichloroethylene). 2. Effects on reproductive performances, egg quality and embryo toxicity in broiler breeders. Poultry Science 76: 1493-1500.Google Scholar
WANG, H., DONG, Y., YANG, Y., TOOR, G.S. and ZHANG, X. (2013) Changes in heavy metal contents in animal feed and manures in an intensive animal production region in China. Journal of Environmental Sciences 25: 2435-2442.Google Scholar
WANG, A., HOLLADAY, S.D., WOLF, D.C., AHMED, S.A. and ROBERTSON, J.L. (2006) Reproductive and developmental toxicity of As in rodents: A review. International Journal of Toxicology 25: 319-331.Google Scholar
WORLD HEALTH ORGANIZATION (2017) MediaCentre: As in food. Fact sheet.Google Scholar
ŽIVKOV BALOŠ, M., MIHALJEV, Ž., ĆUPIĆ, Ž., VUKAŠINOVIĆ, M. and VIDIĆ, B. (2007) Content of toxic elements in raw materials and feed for domestic animals produced in Vojvodina. Proceedings of XII International Feed Technology Symposium, Novi Sad, pp. 353-357.Google Scholar
ŽIVKOV BALOŠ, M., MIHALJEV, Ž., JAKŠIĆ, S., ĆUPIĆ, Ž. and KAPETANOV, M. (2013) Concentration of As in water and tissues of broilers. Proceedings of 10th International Symposium Modern Trends in Livestock Production, Belgrade, pp. 776-783.Google Scholar