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Functions of propolis as a natural feed additive in poultry

Published online by Cambridge University Press:  13 January 2016

U.T. MAHMOUD*
Affiliation:
Dept. of Animal Hygiene, Faculty of Veterinary Medicine, Assiut University, 71526, Egypt
H.W. CHENG
Affiliation:
USDA Agricultural Research Service, 125 S. Russell St. West Lafayette, IN, USA
T.J. APPLEGATE
Affiliation:
Dept. of Animal Sciences, Purdue University, 915 West State Street, West Lafayette, IN 47907, USA
*
Corresponding author: [email protected]
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Abstract

Propolis is a resinous hive product collected by honeybees from various sources of plants. Numerous scientific investigations have been focused on the biological activities of propolis and its functions as a health supplement in humans. It could have similar function in other animals, such as in poultry. This review is focused on the recent findings concerning the effects of propolis, as an antioxidant, on performance, carcass characteristics, behaviour, immunity, and physiological homeostasis in domesticated poultry species (broiler chickens, laying hens, quail, and duck); and the needs in future poultry research.

Type
Reviews
Copyright
Copyright © World's Poultry Science Association 2016 

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References

ABDEL-MOHSEIN, H.S., MAHMOUD, M.A.M. and MAHMOUD, U.T. (2014) Influence of propolis on intestinal microflora of Ross broilers exposed to hot environment. Advances in Animal and Veterinary Sciences 2: 204-211.CrossRefGoogle Scholar
ABDEL-RAHMAN, M.A. and MOSAAD, G.M. (2013) Effect of propolis as additive on some behavioural patterns, performance and blood parameters in Muscovy broiler ducks. Journal of Advanced Veterinary Research 3: 64-68.Google Scholar
AÇIKGÖZ, Z., YÜCEL, B., ALTAN and Ö. (2005) The effects of propolis supplementation on broiler performance and feed digestibility. Archiv für Geflügelkunde 69: 117-122.Google Scholar
ATTIA, Y.A., ABDAL-HAMID, A.E., IBRAHIM, M.S., AL-HARTHI, M.A., BOVERA, F. and ELNAGGAR, A.S. (2014) Productive performance, biochemical and hematological traits of broiler chickens supplemented with propolis, bee pollen, and mannan oligosaccharides continuously or intermittently. Livestock Science 164: 87-95.CrossRefGoogle Scholar
AYGUN, A., SERT, D. and COPUR, G. (2012) Effects of propolis on eggshell microbial activity, hatchability and chick performance in Japanese quail (Coturnix coturnix Japonica) eggs. Poultry Science 91: 1018-1025.CrossRefGoogle ScholarPubMed
BABIŃSKA, I., KLECZEK, K., MAKOWSKI, W. and SZAREK, J. (2013) Effect of feed supplementation with propolis on liver and kidney morphology in broiler chickens. Pakistan Veterinary Journal 33: 1-4.Google Scholar
BABIŃSKA, I., KLECZEK, K., SZAREK, J. and MAKOWSKI, W. (2012) Modulating effect of propolis and bee pollen on chicken breeding parameters and pathomorphology of liver and kidneys in the course of natural infection with Salmonella Enteritidis. The Bulletin of the Veterinary Institute in Pulawy 56: 3-8.CrossRefGoogle Scholar
BANKOVA, V. (2005) Chemical diversity of propolis and the problem of standardization. Journal of Ethnopharmacology 100: 114-117.CrossRefGoogle ScholarPubMed
BONOMI, A., BONOMI, B.M., QUARANTELLI, A., SABBIONI, A. and SUPERCHI, P. (2002) The use of propolis in duck feeding. Rivista di Scienza dell'Alimentazione 31: 15-28.Google Scholar
BANSKOTA, A.H., TEZUKA, Y. and KADOTA, S. (2001) Recent progress in pharmacological research of propolis. Phytotherapy Research 15: 561-571.CrossRefGoogle ScholarPubMed
BIAVATTI, M.W., BELLAVER, M.H., VOLPATO, L., COSTA, C. and BELLAVER, C. (2003) Preliminary studies of alternative feed additives for broilers: Alternanthera brasiliana extract, propolis extract and linseed oil. Revista Brasileira de Ciência Avícola 5: 147-151.CrossRefGoogle Scholar
BONOMI, A., BONOMI, B.M., QUARANTELLI, A., SABBIONI, A. and SUPERCHI, P. (2002) The use of propolis in duck feeding. Rivista di Scienza dell'Alimentazione 31: 15-28.Google Scholar
ÇETIN, E., SILICI, S., ÇETIN, N. and GÜÇLÜ, B.K. (2010) Effects of Diets Containing Different Concentrations of Propolis on Hematological and Immunological Variables in Laying Hens. Poultry Science 89: 1703-1708.CrossRefGoogle ScholarPubMed
CHENG, H.W., SINGLETON, P. and MUIR, W.M. (2002) Social stress in laying hens: differential dopamine and corticosterone responses after intermingling different genetic strains of chickens. Poultry Science 81: 1265-1272.CrossRefGoogle ScholarPubMed
DENLI, M., CANKAYA, S., SILICI, S., OKAN, F. and ULUOCAK, A.N. (2005) Effect of Dietary Addition of Turkish Propolis on the Growth Performance, Carcass Characteristics and Serum Variables of Quail (Coturnix coturnix japonica). Asian-Australasian Journal of Animal Sciences 18: 848-854.CrossRefGoogle Scholar
DIMOV, V., IVANOVSKA, N., MANOLOVA, N., BANKOVA, V., NIKOLAV, N. and POPOV, S. (1991) Immunomodulatory action of propolis. Influence on anti-infectious protection and macrophage function. Apidologie 22: 155-162.CrossRefGoogle Scholar
EDENS, F.W. (2003) An alternative for antibiotic use in poultry: probiotics. Revista Brasileira de Ciência Avícola 5: 75-97.CrossRefGoogle Scholar
EYNG, C., MURAKAMI, A.E., DUARTE, C.R.A. and SANTOS, T.C. (2014) Effect of dietary supplementation with an ethanolic extract of propolis on broiler intestinal morphology and digestive enzyme activity. Journal of Animal Physiology and Animal Nutrition 98: 393-401.CrossRefGoogle ScholarPubMed
EYNG, C., MURAKAMI, A.E., PEDROSO, R.B., SILVEIRA, T.G.V., LOURENCO, D.A.L. and GARCIA, A.F.Q.M. (2013) Crude propolis as an immunostimulating agent in broiler feed during the starter phase. Semina: Ciências Agrárias, Londrina 34: 2511-2522.Google Scholar
FARRÉ, R., FRASQUET, I. and SÁNCHEZ, A. (2004) Propolis and human health. Ars Pharmaceutica 45: 21-43.Google Scholar
FREITAS, J.A., VANAT, N., PINHEIRO, J.W., BALARIN, M.R.S., SFORCIN, J.M. and VENANCIO, E.J. (2011) The Effects of Propolis on Antibody Production by Laying Hens. Poultry Science 90: 1227-1233.CrossRefGoogle ScholarPubMed
GALAL, A., ABD EL-MOTAAL, A.M., AHMED, A.M.H. and ZAKI, T.G. (2008) Productive performance and immune response of laying hens as affected by dietary propolis Supplementation. International Journal of Poultry Science 7: 272-278.CrossRefGoogle Scholar
GREENAWAY, W., MAY, J., SCAYSBROOK, T. and WHATLEY, F.R. (1991) Identification by gas chromatography-mass spectrometry of 150 compounds in propolis. Zeitschrift fur Naturforschung 42: 111-121.CrossRefGoogle Scholar
HAŠČÍK, P., GARLÍK, J., ELIMAM, I.O.E., KAČÁNIOVÁ, M., POCHOP, J., BOBKO, M., KROČKO, M. and BENCZOVÁ, E. (2011) Sensory quality of poultry meat after propolis application. Journal of Microbiology, Biotechnology and Food Sciences 1: 172-186.Google Scholar
HASSAN, M.G. and ABDULLA, T.A. (2011) The effect of propolis feed supplementation on hygiene and performance of broiler chickens. Iraqi Journal of Veterinary Science 25: 77-82.Google Scholar
KLECZEK, K., MAJEWSKA, K., MAKOWSKI, W. And MICHALIK, and , D. (2012) The effect of diet supplementation with propolis and bee pollen on the physicochemical properties and strength of tibial bones in broiler chickens. Archiv Tierzucht 55: 97-103.Google Scholar
KROČKO, M., ČANIGOVÁ, M., BEZEKOVÁ, J., LAVOVÁ, M., HAŠČÍK, P. and DUCKOVÁ, V. (2012) Effect of nutrition with propolis and bee pollen supplements on bacteria colonization pattern in gastrointestinal tract of broiler chickens. Animal Science and Biotechnologies 45: 63-67.Google Scholar
LAXMINARAYAN, R., DUSE, A., WATTAL, C., ZAIDI, A.K., WERTHEIM, H.F., SUMPRADIT, N., VLIEGHE, E., HARA, G.L., GOULD, I.M., GOOSSENS, H., GREKO, C., SO, A.D., BIGDELI, M., TOMSON, G., LEE, M.S., KIM, Y.H., PARK, W.S., AHN, W.G., PARK, O.K., KWON, S.H., MORITA, K., SHIM, I. and HER, S. (2013) Novel antidepressant-like activity of propolis extract mediated by enhanced glucocorticoid receptor function in the hippocampus. Evidence-Based Complementary and Alternative Medicine 2013: 1-10.Google Scholar
LEE, M.S., KIM, Y.H., PARK, W.S., AHN, W.G., PARK, O.K., KWON, S.H., MORITA, K., SHIM, I. and HER, S. (2013) Novel antidepressant-like activity of propolis extract mediated by enhanced glucocorticoid receptor function in the hippocampus. Evidence-Based Complementary and Alternative Medicine 2013: 1-10.Google ScholarPubMed
LEVY, S.B. and MARSHALL, B. (2004) Antibacterial resistance worldwide: causes, challenges and responses. Nature Medicine 10: S122 - S129.CrossRefGoogle ScholarPubMed
MAHMOUD, M.A.M., ABDEL-MOHSEIN, H.S. and MAHMOUD, U.T. (2014b) Effect of Chinese propolis supplementation on Ross broiler chicks: microbial population in fecal matter and litter. Journal of Advanced Veterinary Research 4: 77-84.Google Scholar
MAHMOUD, U.T., ABDEL-RAHMAN, M.A. and DARWISH, M.H.A. (2013) The effect of Chinese propolis supplementation on Ross broiler performance and carcass characteristics. Journal of Advanced Veterinary Research 3: 154-160.Google Scholar
MAHMOUD, U.T., ABDEL-RAHMAN, M.A. and DARWISH, M.H.A. (2014a) Effects of propolis, ascorbic acid and vitamin e on thyroid and corticosterone hormones in heat stressed broilers. Journal of Advanced Veterinary Research 1: 18-27.Google Scholar
MAHMOUD, U.T., ABDEL-RAHMAN, M.A., DARWISH, M.H.A., APPLEGATE, T.J. and CHENG, H.W. (2015) Behavioral changes and feathering score in heat stressed broiler chickens fed diets containing different levels of propolis. Applied Animal Behaviour Science 166: 98-105.CrossRefGoogle Scholar
MAISONNEUVE, E. and GERDES, K. (2014) Molecular Mechanisms underlying bacterial persisters. Cell157: 539-548.CrossRefGoogle ScholarPubMed
MARKHAM, K.E., MITCHEL, K.A., WILKINS, A.L., DALDY, J.A. and LU, Y. (1996) HPLC and GC-MS identification of the major organic constituents in New Zealand propolis. Phytochemistry 42: 205-211.CrossRefGoogle Scholar
MARSHALL, B.M. and LEVY, S.B. (2011) Food Animals and Antimicrobials: Impacts on Human Health. Clinical Microbiology Reviews 24: 718-733.CrossRefGoogle ScholarPubMed
MATSUI, T., EBUCHI, S., FUJISE, T., ABESUNDARA, K.J.M., DOI, S., YAMADA, H. and MATSUMOTO, K. (2004) Strong antihyperglycemic effects of water-soluble fraction of Brazilian propolis and its bioactive constituent, 3,4,5-tri-o-caffeoylquinic acid. Biological and Pharmaceutical Bulletin 27: 1797-1803.CrossRefGoogle Scholar
NEWAIRY, A.A. and ABDOU, H.M. (2013) Effect of propolis consumption on hepatotoxicity and brain damage in male rats exposed to chlorpyrifos. African Journal of Biotechnology 12: 5232-5243.CrossRefGoogle Scholar
OMAR, R.E.M., MAHMOUD, E.A., KAROUSA, M.M. and RANDA, S.A. (2004) Changes in behaviour, performance and blood parameters of Sasso chicks supplemented with propolis and nigella sativa oil in their diets. Journal of the Faculty of Veterinary Medicine Zagazig University - Egypt 32: 57-65.Google Scholar
ORSATTI, C.L. and SFORCIN, J.M. (2012) Propolis immunomodulatory activity on TLR-2 and TLR-4 expression by chronically stressed mice. Natural Product Research 26: 446-453.CrossRefGoogle ScholarPubMed
ORSI, R.O., FUNARI, S.R.C., SOARES, A.M.V.C., CALVI, S.A., OLIVEIRA, S.L., SFORCIN, J.M. and BANKOVA, V. (2000) Immunomodulatory action of propolis on macrophage activation. Journal of Venomous Animals and Toxins including Tropical Diseases, Botucatu 6: 205-219.CrossRefGoogle Scholar
OZKOK, D., ISCAN, K.M. and ILICI, S. (2013) Effects of dietary propolis supplementation on performance and egg quality in laying hens . Journal of Animal and Veterinary Advances 12: 269-275.Google Scholar
PARK, J.H., LEE, J.K., KIM, H.S., CHUNG, S.T., EOM, J.H., KIM, K.A., CHUNG, S.J., PAIK, S.U. and OH, H.Y. (2004) Immunomodulatory effect of caffeic acid phenethyl ester in Balb/c mice. International Immunopharmacology 4: 429-436.CrossRefGoogle ScholarPubMed
PETRUŠKA, P., TUŠIMOVÁ, E., KALAFOVÁ, A., HAŠČÍK, P., KOLESÁROVÁ, A. and CAPCAROVÁ, M. (2012) Effect of propolis in chicken diet on selected parameters of mineral Profile. Journal of Microbiology, Biotechnology and Food Sciences 1: 593-600.Google Scholar
SAMENI, H.R., FATEMEH, K., HASSAN, M.A., REZA, B.A., BEHPOUR, Y. and ALI., T.A. (2014) Effects of hydroalcoholic extract of propolis on oxidative stress indices of rat fetal brain induced by chronic prenatal stress. Koomesh Journal of Semnan University of Medical Sciences 15: 482-492.Google Scholar
SANTOS, A.V., TEIXEIRA, A.S., RODRIGUES, P.B., FREITAS, R.T.F., GUIMARAES, A.M. and GIACOMETTI, R.A. (2003) Nutritive value of propolis residue for broiler chickens. Ciencia e Agrotecnologia 27: 1152-1159.CrossRefGoogle Scholar
SEVEN, I., AKSU, T. and TATLI SEVEN, P. (2010) The Effects of propolis on biochemical parameters and activity of antioxidant enzymes in broilers exposed to lead-induced oxidative stress. Asian - Australasian Journal of Animal Sciences 23: 1482-1489.CrossRefGoogle Scholar
SEVEN, I., AKSU, T. and TATLI SEVEN, P. (2012) The effects of propolis and vitamin c supplemented feed on performance, nutrient utilization and carcass characteristics in broilers exposed to lead. Livestock Science 148: 10-15.CrossRefGoogle Scholar
SEVEN, I., TATLI SEVEN, P. and SILICI, S. (2011) Effects of dietary Turkish propolis as alternative to antibiotic on growth and laying performances, nutrient digestibility and egg quality in laying hens under heat stress. Revue de Médecine Vétérinaire 162: 186-191.Google Scholar
SFORCIN, J.M. (2007) Propolis and the immune system: A review. Journal of Ethnopharmacology 113:1-14.CrossRefGoogle ScholarPubMed
SHALMANY, S.K. AND SHIVAZAD, and , M. (2006) The effect of diet propolis supplementation on ross broiler chicks performance. International Journal of Poultry Science 5: 84-88.Google Scholar
SHIHAB, I.M. and ALI, B.H. (2012) Effect of propolis in diet supplementation on the immune response against Newcastle disease and hematological picture in broiler chicks. Al-Anbar Journal of Veterinary Sciences 5: 40-46.Google Scholar
SMITH, J.L. and FRATAMICO, P.M. (2010) Fluoroquinolone resistance in campylobacter. Journal of Food Protection 73: 1141-1152.CrossRefGoogle ScholarPubMed
TAHERI, H.R., RAHMANI, H.R. and POURREZA, J. (2005) Humoral immunity of broilers is affected by oil extracted propolis (OEP) in the diet. International Journal of Poultry Science 4: 414-417.Google Scholar
TAO, X., ZHANG, Z.Y., DONG, H., ZHANG, H. and XIN, H. (2006) Responses of thyroid hormones of market-size broilers to thermoneutral constant and warm cyclic temperatures. Poultry Science 85: 1520-1528.CrossRefGoogle ScholarPubMed
TATLI SEVEN, P. (2008) The effects of dietary turkish propolis and vitamin c on performance, digestibility, egg production and egg quality in laying hens under different environmental temperatures. Asian - Australasian Journal of Animal Sciences 21: 1164-1170.CrossRefGoogle Scholar
TATLI SEVEN, P. and SEVEN, I. (2008) Effect of Dietary Turkish Propolis as Alternative to Antibiotic on Performance and Digestibility in Broilers Exposed to Heat Stress. Journal of Applied Animal Research 34: 193-196.CrossRefGoogle Scholar
TATLI SEVEN, P., SEVEN, I., YILMAZ, M. and SIMSEK, U.G. (2008) The effects of Turkish propolis on growth and carcass characteristics in broilers under heat stress. Animal Feed Science and Technology 146: 137-148.CrossRefGoogle Scholar
TATLI SEVEN, P., YILMAZ, S., SEVEN, I., CERCI, I.H., AZMAN, M.A. and YILMAZ, M. (2009) Effects of Propolis on Selected Blood Indicators and Antioxidant Enzyme Activities in Broilers under Heat Stress. Acta Veterinaria Brno 78: 75-83.CrossRefGoogle Scholar
TEKELI, A., KUTLU, H.R. and CELIK, L. (2011) Effect of Z. officinale and propolis extracts on the performance, carcass and some blood parameters of broiler chicks. Current Research in Poultry Science 1: 12-23.CrossRefGoogle Scholar
TEKELI, A., KUTLU, H.R., CELIK, L. and DORAN, F. (2010) Determination of the effects of Z. officinale and propolis extracts on intestinal microbiology and histological characteristics in broilers. International Journal of Poultry Science 9: 898-906.CrossRefGoogle Scholar
THORSTEINSDOTTIR, T.R., HARALDSSON, G., FRIDRIKSDOTTIR, V., KRISTINSSON, K.G. and GUNNARSSON, E. (2010) Broiler chickens as source of human fluoroquinolone-resistant Escherichia coli, Iceland. Emerging Infectious Diseases Journal 16: 133-135.CrossRefGoogle ScholarPubMed
VILELA, C.O., VARGAS, G.D., FISCHER, G., LADEIRA, S., DE FARIA, R.O., NUNES, C.F., DE LIMA, M., HÜBNER, S.O., LUZ, P., OSÓRIO, L.G. and ANCIUTI, M.A. (2012) Propolis: A natural product as an alternative for disinfection of embryonated eggs for incubation. Arquivos do Instituto Biológico São Paulo 79: 161-167.CrossRefGoogle Scholar
ZHI-JIANG, Z., SAN-FENG, L., KE, P., HONG-XIANG, W. and KAI-JIE, T. (2004) Effects of pollen and propolis on productive and immune performance in meat fowl. Scientia Agriculura Sinica 37: 751-755.Google Scholar
ZIARAN, H.R., RAHMANI, H.R. and POURREZA, J. (2005) Effect of dietary oil extract of propolis on immune response and broiler performance. Pakistan Journal of Biological Science 8: 1485-1490.Google Scholar