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Dynamics of telomere length in the chicken

Published online by Cambridge University Press:  13 November 2014

S.H. SOHN  and
V.K. SUBRAMANI
S.H. SOHN*
Affiliation:
Department of Animal Science and Biotechnology, Gyeongnam National University of Science and Technology, Jinju 660-758, Republic of Korea
V.K. SUBRAMANI
Affiliation:
Department of Animal Science and Biotechnology, Gyeongnam National University of Science and Technology, Jinju 660-758, Republic of Korea
*
Corresponding author: [email protected]
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Abstract

Telomeres are specialised nucleoprotein end structures of eukaryotic chromosomes and protect and maintain genome integrity from recombination, exonuclease degradation and end-to-end fusion. Because of the end replication problem, telomere length in somatic cells tends to decrease with organismal age. Telomere shortening is known to occur in chicken somatic tissues and correlates with advanced developmental age. However, age is not the only determinant of telomere length in an individual. Several factors at the genetic and epigenetic levels are known to affect telomere length in different ways. Herein, we review several factors that affect telomere length in the chicken. Genetic factors include breed and sex, while the epigenetic factors include environmental and stochastic influences. Age, stocking density and living or housing systems were reviewed as environmental factors pertaining to the habitat of the organism. Factors such as oxidative stress, antioxidants in feed and restriction feeding were the stochastic factors that we reviewed.

Keywords

chickentelomeregenetic factorsepigenetic factorsenvironmental factors
Type
Review Article
Information
World's Poultry Science Journal , Volume 70 , Issue 4 , December 2014 , pp. 721 - 736
Copyright
Copyright © World's Poultry Science Association 2014 

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