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Inclusion body hepatitis–anaemia and hydropericardium syndromes: aetiology and control*

Published online by Cambridge University Press:  18 September 2007

Barrett S. Cowen
Affiliation:
The Pennsylvania State University, Department of Veterinary Science, Wiley Laboratory, University Park, Pennsylvania 16802, USA
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Abstract

Clinical and pathological descriptions of inclusion body hepatitis–anaemia syndrome (IBH–AS) and hydropericardium syndrome (HpS) are presented and their causation and control are discussed. IBH–AS is a disease which has generally been thought to have a multiple aetiology, including infectious bursal disease virus, avian adenovirus and probably chicken anaemia virus. However, there is new evidence which suggests that avian adenoviruses are primary pathogens in IBH–AS. HpS is a new broiler disease which has spread throughout Pakistan. It has a number of similarities with IBH–AS. Recently, outbreaks of a disease exhibiting features of IBH–AS and HpS have been observed in North and South America. Mortality has been reported to be higher than is usual for IBH–AS and some hydropericardium has been observed.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1992

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References

Afzal, M. and Ahmad, I. (1990) Efficacy of an inactivated vaccine against hydropericardium syndrome in broilers. Veterinary Record 126: 56Google ScholarPubMed
Afzal, M., Muneer, R., Stein, G. Jr and Cowen, B.S. (1990) Etiology and control of hydropericardium syndrome (Angara disease) in broilers of Pakistan. Proceedings of 3rd International Congress, Pakistan Veterinary Medical Association,Islamabad, Pakistan, pp. 1–20Google Scholar
Ahmad, I., Afzal, M., Malik, M.I., Hussain, Z. and Hanif, W. (1988) Studies on the disease pattern and etiology of hydropericardium syndrome (Angara disease) in broiler chickens in Pakistan. Pakistan Journal of Agricultural Research 10: 195199Google Scholar
Ahmad, I., Ahmad, K. and Malik, M.I. (1990) Comparative efficacy of different Angara disease vaccines in broilers. Veterinarski Archiv (in press)Google Scholar
Anjum, A.D., Sabri, M.A. and Iqbal, Z. (1989) Hydropericarditis syndrome in broiler chickens in Pakistan. Veterinary Record 124: 247248CrossRefGoogle ScholarPubMed
Bickford, A.A., Krasovich, M.A. and Fadly, A.M. (1973) Demonstration of virus particles in hepatic cells of chickens with inclusion body hepatitis. Avian Diseases 17: 629638CrossRefGoogle ScholarPubMed
Bulow, V.v., Rudolph, R. and Fuchs, B. (1986) Folgen der doppenlinfektion von küken mit adenovirus oder reovirus and dem erreger der wiären infektiosen anämie (CAA). Journal of Veterinary Medicine B33: 717CrossRefGoogle Scholar
Cheema, A.H., Afzal, M. and Ahmad, J. (1989) An adenovirus infection of poultry in Pakistan. Revue Scientifique Technologique, International Epizootics 8: 789798Google ScholarPubMed
Christensen, N.H. and Saifuddin, Md. (1989) A primary epidemic of inclusion body hepatitis in broilers. Avian Diseases 33: 622630CrossRefGoogle ScholarPubMed
Cook, J.K.A. (1974) Pathogenicity of avian adenoviruses for day-old chicks. Journal of Comparative Pathology 84: 505515CrossRefGoogle ScholarPubMed
Cowen, B.S. (1977) Avian adenovirus pathogenicity and isolant serotype. Journal of the American Veterinary Medicine Association 171: 11061107Google Scholar
Cowen, B.S. and Naqi, S.A. (1982) Classification of avian adenoviruses. Journal of the American Veterinary Medicine Association 181: 283Google Scholar
Cubillos, A., Sandoval, G., Ulloa, J., Cubillos, V. and Aguilar, M. (1986) Aislamiento y tepificacion del virus hepatitis a cuerpo de inclusion en broilers, en Chile. Archives de Medicina Veterinaria (Valdivia) 18: 115122Google Scholar
Erny, K.M., Barr, D.A. and Fahey, K.J. (1991) Molecular characterization of highly virulent fowl adenoviruses associated with outbreaks of inclusion body hepatitis. Avian Pathology 20: 597606CrossRefGoogle ScholarPubMed
Fadly, A.M. (1975) PhD Dissertation, Purdue University, USAGoogle Scholar
Fadly, A.M. and Winterfield, R.W. (1973) Isolation and some characteristics of an agent associated with inclusion body hepatitis, hemorrhages and aplastic anemia in chickens. Avian Diseases 17: 182193CrossRefGoogle ScholarPubMed
Fadly, A.M., Winterfield, R.W. and Olander, H.J. (1976) Role of bursa of Fabricius in the pathogenicity of inclusion body hepatitis and infectious bursal disease viruses. Avian Diseases 20: 467477CrossRefGoogle ScholarPubMed
Guy, J.S., Schaeffer, J.L. and Barnes, H.J. (1988) Inclusion-body hepatitis in day-old turkeys. Avian Diseases 32: 587590CrossRefGoogle ScholarPubMed
Hassan, S.A. (1989) Pakistan is mystified by Hydropericardium Syndrome. Poultry Misset 5: 3537Google Scholar
Helmboldt, C.F. and Frazier, M.N. (1963) Avian hepatic inclusion bodies of unknown significance. Avian Diseases 7: 446450CrossRefGoogle ScholarPubMed
Howell, J., Macdonald, D.W. and Christian, R.G. (1970) Inclusion body hepatitis in chickens. Canadian Veterinary Journal 11: 99101Google ScholarPubMed
Jaffrey, M.S. (1988) A Treatise on Angara Disease in Chicken. Pakistan Veterinary Medical Association, Karachi, pp. 133Google Scholar
Jalalee, M.A. (1988) Hydropericardium in chickens. In: Proceedings of National Seminar on Hydropericardium Syndrome. Poultry Development Centre (PRI), Rawalpindi, Pakistan, pp. 8395Google Scholar
Kawamura, H., Sato, T., Tsubahara, H. and Isogai, S. (1963) Isolation of CELO virus from chicken trachea. National Institute of Animal Health Quarterly (Tokyo) 3: 110Google Scholar
Kefford, B. and Borland, R. (1979) Isolation of a serotype 8 avian adenovirus associated with inclusion body hepatitis. Australian Veterinary Journal 55: 599CrossRefGoogle ScholarPubMed
Khawaja, D.A., Ahmed, S., Rauf, A.M., Zulfigar, M., Mahmood, S.M.I. and Hassan, M. (1988) Isolation of an adenovirus from hydropericardium syndrome in broiler chicks. Pakistan Journal of Veterinary Research 1: 217Google Scholar
Macpherson, I., McDougall, J.S. and Laursen-Jones, A.P. (1974) Inclusion body hepatitis in a broiler integration. Veterinary Record 95: 286289CrossRefGoogle Scholar
McDougall, J.S. and Peters, R.W. (1974) Avian adenoviruses: a study of 8 field isolates. Research in Veterinary Science 16: 1218CrossRefGoogle ScholarPubMed
McFerran, J.B. and Connor, T.J. (1977) Further studies on the classification of fowl adenoviruses. Avian Diseases 21: 585595CrossRefGoogle ScholarPubMed
McFerran, J.B., McCracken, R.M., Connor, T.J. and Evans, R.T. (1976) Isolation of viruses from clinical outbreaks of inclusion body hepatitis. Avian Pathology 5: 315324CrossRefGoogle ScholarPubMed
Muneer, M.A., Ajmal, M., Arshad, M., Ahmad, M.D., Chaudhry, Z.I. and Khun, T.M. (1989) Preliminary studies on hydropericardium syndrome in broilers in Pakistan. Zootechnica International May, 4648Google Scholar
Pettit, J.R. and Carlson, H.C. (1972) Inclusion body hepatitis in broiler chickens. Avian Diseases 16: 858865CrossRefGoogle ScholarPubMed
Qureshi, A.A. (1988) Hydropericardium and kidney lesions. Poultry International 27: 4849Google Scholar
Qureshi, A.A. (1989) Hydropericardium and ascites. Poultry International 28: 4448Google Scholar
Reece, R.L., Barr, D.A., Grix, D.C., Forsyth, W.M., Condron, R.J. and Hindmarsh, M. (1986) Observations on naturally occurring inclusion body hepatitis in Victorian chickens. Australian Veterinary Journal 63: 201202CrossRefGoogle ScholarPubMed
Riddell, C. (1984) Viral hepatitis in domestic geese in Saskatchewan. Avian Diseases 28: 774782CrossRefGoogle ScholarPubMed
Rinaldi, A., Mandelli, F., Cessi, D., Caleri, A. and Gervio, G. (1968) Properties of a strain of CELO virus isolatead from chickens in Italy. Clinica Veterinaria 91: 382404Google Scholar
Rosen, M.N., Hunter, B.F. and Brunetti, O.A. (1965) Preliminary study of an infectious hepatitis in pheasants. Avian Diseases 9: 382393CrossRefGoogle ScholarPubMed
Rosenberger, J.K., Klopp, S., Eckroade, R.F. and Krauss, W.C. (1975) The role of the infectious bursal agent and several avian adenoviruses in the haemorrhagic–aplastic anemia syndrome and gangrenous dermatitis. Avian Diseases 19: 717729CrossRefGoogle Scholar
Saifuddin, Md. and Wilks, C.R. (1990) Reproduction of inclusion body hepatitis in conventionally raised chickens inoculated with a New Zealand isolate of avian adenovirus. New Zealand Veterinary Journal 38: 6265CrossRefGoogle ScholarPubMed
Scott, P.C., Condron, R.J. and Reece, R.L. (1986) Inclusion body hepatitis associated with adenovirus-like particles in a cockatiel (Psittaciformes; Nyphicus hollandicus). Australian Veterinary Journal 63: 337CrossRefGoogle Scholar
Tariq, M.A. (1988) Preliminary studies on hydropericardium syndrome in broiler chicks and its control measures in Pakistan. Proceedings of National Seminar on Hydropericardium Syndrome.Poultry Development Centre (PRI),Rawalpindi, Pakistan, pp. 49–57Google Scholar
Wells, R.J.H. and Harrigan, K. (1974) A fatal adenovirus infection of broiler chickens: inclusion body hepatitis. Veterinary Record 94: 481482CrossRefGoogle ScholarPubMed
Winterfield, R.W. (1984) Avian adenovirus infections. In: Diseases of Poultry (Eds. Hofstad, M.S., Barnes, H.F., Calnek, B.W., Reis, W.M. and Yoder, H.W.), Iowa State University Press, Ames, Iowa, pp. 497506Google Scholar
Winterfield, R.W., Fadly, A.M. and Gallina, A.M. (1973) Adenovirus and disease. I. Some characteristics of an isolate from chickens in Indiana. Avian Diseases 17: 334342CrossRefGoogle ScholarPubMed
Young, J.A., Purcell, D.A. and Kavanagh, P.J. (1972) Inclusion body hepatitis outbreak in broiler flocks. Veterinary Record 90: 72CrossRefGoogle ScholarPubMed