Hostname: page-component-cd9895bd7-gvvz8 Total loading time: 0 Render date: 2024-12-28T11:27:35.505Z Has data issue: false hasContentIssue false
  • English
  • Français

Herbicide Inputs for a New Agronomic Crop, Annual Wormwood (Artemisia annua)

Published online by Cambridge University Press:  12 June 2017

Charles T. Bryson  and
Edward M. Croom Jr.
Charles T. Bryson
Affiliation:
U. S. Dep. Agric., Agric. Res. Serv., South. Weed Sci. Lab., P.O. Box 350, Stoneville, MS 38776
Edward M. Croom Jr.
Affiliation:
Res. Inst. of Pharm. Sci., School of Pharmacy, Univ. Miss., University, MS 38677
Get access Rights & Permissions [Opens in a new window]

Abstract

Annual wormwood has been cultivated on a small scale for production of the artemisinin class of antimalarial drugs in sufficient quantities for preclinical and clinical trials. Large scale cultivation will require a reliable, efficient crop production system. Production systems using 32 herbicides alone or in combinations were evaluated in growth chamber, greenhouse, and field experiments at Stoneville, MS from 1985 through 1988. The herbicide treatments that provided the best weed control were (A) metolachlor at 2.2 kg ai ha-1 preemergence (PRE), (B) chloramben at 2.2 kg ai ha-1 (PRE), or (C) trifluralin at 0.6 kg ai ha-1 preplant soil incorporated (PPI) followed by fluazifop at 0.2 + 0.2 kg ai ha-1 postemergence broadcast (POST) and acifluorfen at 0.6 kg ai ha-1 (POST). These herbicide production systems provided excellent weed control (≥85%) and minimal crop injury (≤10%) with no effect on crop height or weight at harvest. Production of artemisinin was not reduced by herbicide treatments A, B, and C in 1987 and treatments B and C in 1988 when compared with the hand-weeded plots.

Keywords

Acifluorfen, 5-[2-chloro-4-(trifluoromethyl)phenoxy]-2-nitrobenzoic acidchloramben, 3-amino-2,5-dichlorobenzoic acidfluazifop (±)-2-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenoxy]propanoic acidmetolachlor, 2-chloro-N-(2-ethyl-6-methylphenyl)-N-(2-methoxy-1-methylethyl)acetamidetrifluralin, 2,6-dinitro-N,N-dipropyl-4-(trifluoromethyl)benzenamineannual wormwood, Artemisia annua L. ♯ ARTANArtemisininantimalarial drugweed controlcrop production systemARTAN
Type
Research
Information
Weed Technology , Volume 5 , Issue 1 , March 1991 , pp. 117 - 124
Copyright
Copyright © 1990 by the Weed Science Society of America 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Literature Cited

1. Duke, S. O., Vaughn, K. C., Croom, E. M. Jr., and Elsohly, H. N. 1987. Artemisinin, a constituent of annual wormwood (Artemisia annua), is a selective phytotoxin. Weed Sci. 35:499–505.Google Scholar
2. Hoagland, D. R., and Anion, D. I. 1950. The water culture method for growing plants without soil. Calif. Agr. Exp. Stn. Circ. 347.Google Scholar
3. Klayman, D. L., Lin, A. L., Acton, N., Scovill, J. P., Hoch, J. M., Milhous, W. K., and Theohardies, A. D. 1984. Isolation of artimisin in (qinghaosu) from Artemisia annua growing in the United States. J. Nat. Prod. 47:715–717.Google Scholar
4. Klayman, D. L. 1985. Qinghaosu (Artemisinin): An antimalarial drug from China. Science 228:1049–1055.Google Scholar
5. McWhorter, C. G., and Holstun, J. T. Jr. 1961. Phytotoxicity of s-triazine herbicides to corn and weeds related to structural differences. Weeds 9:592–599.Google Scholar
6. McWhorter, C. G. 1963. Effects of s-triazines on toxicity to soybeans and weeds. Weeds 11:279–283.Google Scholar
7. World Health Organization. 1988. The development of artemisinin and its derivatives. WHO/TDR/CHEMAL/ART 86.3.Google Scholar
8. You-you, T., Mu-yun, N., Yu-rong, Z., Lan-na, L., Shu-lian, C., Muqun, Z., Xiu-zhen, W., Zheng, J., and Xiano-tian, L. 1982. Studies on the constituents of Artemisia annua Part II. Planta Medica 44:143–145.Google Scholar
9. Maurice, J., and Pearce, A. M., ed. 1987. Tropical Disease Research: A Global Partnership. World Health Organization, Geneva.Google Scholar