Hostname: page-component-78c5997874-t5tsf Total loading time: 0 Render date: 2024-11-10T05:10:03.342Z Has data issue: false hasContentIssue false
  • English
  • Français

Selective Labeling of Visual Corpus Callosum Connections with Aspartate in Cat and Rat?

Published online by Cambridge University Press:  02 June 2009

Andrea J. Elberger
Andrea J. Elberger
Affiliation:
Department of Anatomy and Neurobiology, University of Tennessee, Memphis
Get access Rights & Permissions [Opens in a new window]

Abstract

Tritiated neurotransmitter candidates were unilaterally injected in visual cortical regions with abundant corpus callosum connections. D-aspartate (Asp) or gamma-aminobutyric acid (GABA) was injected along the area 17/18 border in cat, and the area 17/18a and 17/18b borders in rat. Retrograde Asp label was found contralaterally in supragranular and infragranular laminae in areas 17, 18, 19, PMLS, and PLLS in cat, and in areas 29, 18b, 17, and 18a in rat. No contralateral GABA label was found in cat or rat. Thus, the cat and rat corpus callosum may use Asp or a related substance as a neurotransmitter.

Keywords

Corpus callosumAspartateNeurotransmitterVisual cortexGABA
Type
Short Communication
Information
Visual Neuroscience , Volume 2 , Issue 1 , January 1989 , pp. 81 - 85
Copyright
Copyright © Cambridge University Press 1989

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Baughman, R.W. & Gilbert, C.D. (1980). Aspartate and glutamate as possible neurotransmitters of cells in layer 6 of the visual cortex. Nature 287, 848–850.Google Scholar
Baughman, R.W. & Gilbert, C.D. (1981). Aspartate and glutamate as possible neurotransmitters in the visual cortex. Journal of Neuroscience 1, 427–439.Google Scholar
Bosler, O., Beaudet, A. & Pickel, V.M. (1986). Characterization of chemically defined neurons and their cellular relationships by combined immunocytochemistry and radioautographic localization of transmitter uptake sites. Journal of Electron Microscopy Technique 4, 21–39.Google Scholar
Cuenod, M., Beaudet, A., Canzek, V., Streit, P. & Reubi, J.C. (1981). Glutamatergic pathways in the pigeon and the rat brain. In Glutamate As a Neurotransmitter, ed. DiChiara, G. & Gessa, G.L., pp. 57–68. New York: Raven.Google Scholar
Cuenod, M. & Streit, P. (1983). Neuronal tracing using retrograde migration of labeled transmitter-related compounds. In Handbook of Chemical Neuroanatomy, Vol. I, ed. Bjorklund, A. & Hokfelt, T., pp. 365–397. Amsterdam: Elsevier.Google Scholar
Divac, I., Fonnum, F. & Storm-Mathisen, J. (1977). High-affinity uptake of glutamate in terminals of corticostriatal axons. Nature 266, 377–378.Google Scholar
Elberger, A.J. (1982). The functional role of the corpus callosum in the developing visual system: a review. Progress in Neurobiology 18, 15–79.Google Scholar
Elberger, A.J. (1986). Visual cortical afferents and efferents with possible excitatory and inhibitory neurotransmitters in the cat: ipsilateral and corpus callosum pathways. Society for Neuroscience Abstracts 12, 585.Google Scholar
Elberger, A.J. & Looney, G.A. (1985). Visual cortical pathways via the corpus callosum with possible excitatory neurotransmitters in the rat. Society for Neuroscience Abstracts 11, 650.Google Scholar
Emson, P.C. & Lindvall, O. (1979). Distribution of putative neurotransmitters in the neocortex. Neuroscience 4, 1–30.Google Scholar
Fischer, B.O., Ottersen, O.P. & Storm-Mathisen, J. (1982). Axonal transport of D-(3H) aspartate in the claustro-cortical projection. Neuroscience (Suppl.) 7, S69.Google Scholar
Fosse, V.M., Heggelund, P., Iversen, E. & Fonnum, F. (1984). Effects of area 17 ablation on neurotransmitter parameters in efferents to area 18, the lateral geniculate body, pulvinar and superior colliculus in the cat. Neuroscience Letters 52, 323–328.Google Scholar
Hall, K., Brauth, S.E. & Kitt, C.A. (1984). Retrograde transport of [3H]GABA in the striatotegmental system of the pigeon. Brain Research 310, 157–163.Google Scholar
Harandi, M., Didier, M., Aguera, M., Calas, A. & Belin, M.F. (1986). GABA and serotonin (5-HT) pattern in the supraependymal fibers of the rat epithalamus: combined radioautographic and immunocytochemical studies. Effect of 5-HT content on [3H]GABA accumulation. Brain Research 370, 241–249.Google Scholar
Hicks, T.P. & Guedes, R.C.A. (1981). Synaptic transmission in suprasylvian visual cortex is reduced by excitatory amino acid antagonists. Canadian Journal of Physiological Pharmacology 59, 893–896.Google Scholar
Hicks, T.P. & Guedes, R.C.A. (1983). Neuropharmacological properties of electrophysiologically identified, visually responsive neurones of the posterior lateral suprasylvian area. Experimental Brain Research 49, 157–173.Google Scholar
Hicks, T.P., Ruwe, W.D., Veale, W.L. & Veenhuizen, J. (1985). Aspartate and glutamate as synaptic transmitters of parallel visual cortical pathways. Experimental Brain Research 58, 421–425.CrossRefGoogle ScholarPubMed
Hokfelt, T. & Ljungdahl, A. (1975). Uptake mechanisms as a basis for the histochemical identification and tracing of transmitter-specific neuron populations. In The Use of Axonal Transport For Studies of Neuronal Connectivity, ed. Cowan, W.M. & Cuenod, M., pp. 249–305. Amsterdam: Elsevier.Google Scholar
Iversen, L.L. (1978). Identification of transmitter-specific neurons in CNS by autoradiographic techniques. In Handbook of Psychopharmacology, Vol. 9, 9: Chemical Pathways In The Brain, ed. Iversen, L.L., Iversen, S.D. & Snyder, S.H., pp. 41–68. New York: Plenum.Google Scholar
Iversen, L.L. & Schon, F. (1973). The use of autoradiographic techniques for the identification and mapping of transmitter-specific neurons in CNS. In New Concepts In Neurotransmitter Regulation, ed. Mandell, A.J., pp. 153–193. New York: Plenum.CrossRefGoogle Scholar
Kisvarday, Z.F., Cowey, A., Hodgson, A.J. & Somogyi, P. (1986). The relationship between GABA immunoreactivity and labelling by local uptake of [3H]GABA in the striate cortex of monkey. Experimental Brain Research 62, 89–98.CrossRefGoogle ScholarPubMed
Kvale, I. & Fonnum, F. (1983). The effects of unilateral neonatal removal of visual cortex on transmitter parameters in the adult superior colliculus and lateral geniculate body. Developmental Brain Research 11, 261–266.Google Scholar
LeVay, S. & Sherk, H. (1981). The visual claustrum of the cat, I: Structure and connections. Journal of Neuroscience 1, 956–980.CrossRefGoogle ScholarPubMed
Levi, G., Wilkin, G.P., Ciotti, M.T. & Johnstone, S. (1983). Enrichment of differentiated, stellate astrocytes in cerebellar interneuron cultures as studied by GFAP immunofluorescence and autoradiographic uptake patterns with [3H]D-aspartate and [3H]GABA. Developmental Brain Research 10, 227–241.Google Scholar
Miller, M.W. & Vogt, B.A. (1984). Heterotopic and homotopic callosal connections in rat visual cortex. Brain Research 297, 75–89.Google Scholar
Ottersen, O.P., Fischer, B.O. & Storm-Mathisen, J. (1983). Retrograde transport of D-[3H]Aspartate in thalamocortical neurones. Neuroscience Letters 42, 19–24.CrossRefGoogle Scholar
Segraves, M.A. & Rosenquist, A.C. (1982 a). The distribution of the cells of origin of callosal projections in cat visual cortex. Journal of Neuroscience 2, 1079–1089.Google Scholar
Segraves, M.A. & Rosenquist, A.C. (1982 b). The afferent and efferent callosal connections of retinotopically defined areas in cat cortex. Journal of Neuroscience 2, 1090–1107.Google Scholar
Streit, P. (1980). Selective retrograde labeling indicating the transmitter of neuronal pathways. Journal of Comparative Neurology 191, 429–463.CrossRefGoogle ScholarPubMed