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Gaze field properties of eye position neurones in areas MST and 7a of the macaque monkey

Published online by Cambridge University Press:  02 June 2009

S. Squatrito  and
M. G. Maioli
S. Squatrito
Affiliation:
Department of Physiology, University of Trieste, Italy
M. G. Maioli
Affiliation:
Department of Physiology, University of Bologna, Italy
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Abstract

The activity of parietal cortex neurones primarily related to eye position (EP neurones) was studied in macaque monkeys with the aim of precisely defining the neurones' gaze fields (GF) and comparing them in two functionally different areas, MSTd and 7a. Discharge rates of single neurones in the inferior parietal lobule and in the underlying cortex of the superior temporal sulcus were recorded in two Java monkeys while the animals fixated a steady visual target positioned at several different points on a video screen. The GFs were then drawn as a regression surface fitting the mean discharge rates. Cells tonically influenced by the angle of gaze were found in both areas. The GFs most often took the form of a nearly planar surface best characterized as a ramp tilted towards a hemifield or quadrant of the visual field, shifted eccentrically with respect to the straight ahead (primary position), and with a midpoint centred between 0 deg and 20 deg of gaze eccentricity and saturation between 10 deg and 35 deg. In a minority of cases, the discharge rate was nearly maximal at the primary position and decreased to a minimum within 35 deg of eccentricity. In other instances, the GFs were peaked surfaces, limited to a restricted part of visual space. EP neurones, while showing similar gaze fields in areas MST and 7a, were found intermingled with functionally different types of cells. The results suggest that EP neurones similar to those already described in several areas of the monkey parietal cortex are present also in area MST. These cells, by signalling the degree of gaze eccentricity from the primary position, encode gaze position in an orbito-centered frame extending up to 30–35 deg from the straight-ahead. The role of EP neurones might be to supply contiguous elements with a gaze eccentricity signal required for visuo-motor processes such as the control of tracking movements.

Keywords

Oculomotor systemEye positionParietal cortexMacaque monkey
Type
Research Articles
Information
Visual Neuroscience , Volume 13 , Issue 2 , March 1996 , pp. 385 - 398
Copyright
Copyright © Cambridge University Press 1996

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References

REFERENCES

Andersen, R.A. & Mountcastle, V.B. (1983). The influence of the angle of gaze upon the excitability of the light-sensitive neurons of the posterior parietal cortex. Journal of Neuroscience 3, 532–548.CrossRefGoogle ScholarPubMed
Andersen, R.A., Asanuma, C. & Cowan, W.M. (1985 a). Callosal and prefrontal associational projecting cell populations in area 7A of the macaque monkey: A study using retrogradely transported fluorescent dyes. Journal of Comparative Neurology 232, 443–455.Google Scholar
Andersen, R.A., Essick, G.K. & Siegel, R.M. (1985 b). Encoding of spatial location by posterior parietal neurons. Science 230, 456–458.CrossRefGoogle ScholarPubMed
Andersen, R.A., Essick, G.K. & Siegel, R.M. (1987). Neurons of area-7 activated by both visual stimuli and oculomotor behavior. Experimental Brain Research 67, 316–322.CrossRefGoogle ScholarPubMed
Andersen, R.A., Asanuma, C., Essick, G. & Siegel, R.M. (1990 a). Corticocortical connections of anatomically and physiologically defined subdivisions within the inferior parietal lobule. Journal of Comparative Neurology 296, 65–113.CrossRefGoogle ScholarPubMed
Andersen, R.A., Bracewell, R.M., Barash, S., Gnadt, J.W. & Fogassi, L. (1990 b). Eye position effects on visual, memory, and saccade-related activity in areas LIP and 7a of macaque. Journal of Neuroscience 10, 1176–1196.Google Scholar
Bach, M., Bouis, D. & Fischer, B. (1983). An accurate and linear infrared oculometer. Journal of Neuroscience Methods 9, 9–14.CrossRefGoogle ScholarPubMed
Bizzi, E. (1968). Discharge of frontal eye field neurons during saccades and following eye movements in unanesthetized monkeys. Experimental Brain Research 6, 69–80.Google Scholar
Desimone, R. & Ungerleider, L.G. (1986). Multiple visual areas in the caudal superior temporal sulcus of the macaque. Journal of Comparative Neurology 248, 164–189.CrossRefGoogle ScholarPubMed
Draper, N. & Smith, H. (1981). Applied regression analysis. New York: Wiley & Sons.Google Scholar
Duffy, C.J. & Wurtz, R.H. (1991). Sensitivity of MST neurons to optic flow stimuli. I. A continuum of response selectivity to large-field stimuli. Journal of Neurophysiology 65, 1329–1345.Google Scholar
Galletti, C. & Battaglini, P.P. (1989). Gaze-dependent visual neurons in area V3A of monkey prestriate cortex. Journal of Neuroscience 9, 1112–1125.Google Scholar
Galletti, C., Battaglini, P.P. & Fattori, P. (1991). Functional properties of neurons in the anterior bank of the parieto-occipital sulcus of the macaque monkey. European Journal of Neuroscience 3, 452–461.CrossRefGoogle ScholarPubMed
Guthrie, B.L., Porter, J.D. & Sparks, D.L. (1983). Corollary discharge provides accurate eye position information to the oculomotor system. Science 221, 1193–1195.Google Scholar
Hikosaka, K., Iwai, E., Saito, H.-K. & Tanaka, K. (1988). Polysensory properties of neurons in the anterior bank of the caudal superior temporal sulcus of the macaque monkey. Journal of Neurophysiology 60, 1615–1637.CrossRefGoogle ScholarPubMed
Komatsu, H. & Wurtz, R.H. (1988). Relation of cortical areas MT and MST to pursuit eye movement. I. Localization and visual properties of neurons. Journal of Neurophysiology 60, 580–603.Google Scholar
Lal, R. & Friedlander, M.J. (1990). Effect of passive eye position changes on retinogeniculate transmission in the cat. Journal of Neurophysiology 63, 502–522.Google Scholar
Luschei, E.S. & Fuchs, A.F. (1972). Activity of brain stem neurons during eye movements of alert monkey. Journal of Neurophysiology 35, 445–461.Google Scholar
Lynch, J.C., Mountcastle, V.B., Talbot, W.H. & Yin, T.C.T. (1977). Parietal lobe mechanisms for directed visual attention. Journal of Neurophysiology 40, 362–389.Google Scholar
Motter, B.C. & Mountcastle, V.B. (1981). The functional properties of the light-sensitive neurons of the posterior parietal cortex studied in waking monkeys: Foveal sparing and opponent vector organization. Journal of Neuroscience 1, 3–26.Google Scholar
Mountcastle, V.B., Lynch, J.C., Georgopoulos, A., Sakata, H. & Acuna, C. (1975). Posterior parietal association cortex of the monkey: Command functions for operations within extrapersonal space. Journal of Neurophysiology 38, 871–908.CrossRefGoogle ScholarPubMed
Noda, H. & Suzuki, D.A. (1979). Processing of eye movement signals in the flocculus of the monkey. Journal of Physiology 294, 349–364.Google Scholar
Peck, C.K. (1986). Eye position signals in cat superior colliculus. Experimental Brain Research 61, 447–450.CrossRefGoogle ScholarPubMed
Robinson, D.A. (1970). Oculomotor unit behavior in the monkey. Journal of Neurophysiology 33, 393–404.CrossRefGoogle ScholarPubMed
Robinson, C.J. & Burton, H. (1980). Organization of somatosensory receptive fields in cortical areas 7b, retroinsula, postauditory and granular insula of M. Fascicularis. Journal of Comparative Neurology 192, 69–92.Google Scholar
Robinson, D.L., McClurkin, J.W. & Kertzman, C. (1990). Orbital position and eye movement influences on visual responses in the pulvinar nuclei of the behaving macaque. Experimental Brain Research 82, 235–246.Google Scholar
Sakata, H., Shibutani, H. & Kawano, K. (1980). Spatial properties of visual fixation neurons in posterior parietal association cortex of the monkey. Journal of Neurophysiology 43, 1654–1672.CrossRefGoogle ScholarPubMed
Schlag, J., Schlag-Rey, M., Peck, C.K. & Joseph, J.P. (1980). Visual responses of thalamic neurons depending on the direction of gaze and the position of targets in space. Experimental Brain Research 40, 170–184.CrossRefGoogle ScholarPubMed
Squatrito, S. & Maioli, M.G. (1993). Activity profiles of eye position and pursuit neurons in the dorsal bank of the macaque superior temporal sulcus. Society for Neuroscience Abstracts 19, 770.Google Scholar
Steinmetz, M.A., Motter, B.C., Duffy, C.J. & Mountcastle, V.B. (1987). Functional properties of parietal visual neurons: Radial organization of directionalities within the visual field. Journal of Neuroscience 7, 177–191.Google Scholar
Steinbach, M.J. (1987). Proprioceptive knowledge of eye position. Vision Research 27, 1737–1744.Google Scholar
Tanaka, K., Hikosaka, K., Saito, H., Yukie, M., Fukada, Y. & Iwai, E. (1986). Analysis of local and wide-field movements in the superior temporal visual areas of the macaque monkey. Journal of Neuroscience 6, 134–144.Google Scholar
Ungerleider, L.G. & Desimone, R. (1986). Cortical connections of visual area MT in the macaque. Journal of Comparative Neurology 248, 190–222.Google Scholar
Van Essen, D.C. & Maunsell, J.H.R. (1980). Two-dimensional maps of the cerebral cortex. Journal of Comparative Neurology 191, 255–281.Google Scholar
Van Essen, D.C., Maunsell, J.H.R. & Bixby, J.L. (1981). The middle temporal visual area in the macaque: Myeloarchitecture, connections, functional properties and topographic representation. Journal of Comparative Neurology 199, 293–326.CrossRefGoogle Scholar