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Development of lateral interactions in the infant visual system

Published online by Cambridge University Press:  02 June 2009

Samuel Sokol ,
Vance Zemon  and
Anne Moskowitz
Samuel Sokol
Affiliation:
New England Eye Center, New England Medical Center and Tufts University School of Medicine, Boston
Vance Zemon
Affiliation:
New England Eye Center, New England Medical Center and Tufts University School of Medicine, Boston Laboratory of Biophysics, Rockefeller University, New York
Anne Moskowitz
Affiliation:
New England Eye Center, New England Medical Center and Tufts University School of Medicine, Boston
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Abstract

The development of lateral inhibitory interactions in the infant visual system, as reflected by the visual-evoked potential (VEP), was studied using a radial, asymmetrical windmill-dartboard stimulus. This contrast-reversing stimulus generates VEP responses with a strong fundamental frequency component and an attenuated second harmonic component (relative to that obtained using a symmetrical stimulus). These two harmonic components reflect distinct phenomena, and appear to be the result of short-range (the fundamental) and long-range (attenuated second harmonic) lateral inhibitory interactions elicited by differential luminance-modulation of contiguous spatial regions. We studied the development of the short-and long-range interactions at 100% and 30% contrast in human infants using both VEP amplitude and phase measures. Attenuation of the second harmonic (long-range interactions) was adult-like by 8 weeks of age while the strength of the fundamental (short-range interactions) was adult-like by 20 weeks suggesting a differential development of long-range and short-range interactions. In contrast, corresponding phase data indicated significant immaturities at 20 weeks of age for both the short-and long-range components.

Keywords

Visual developmentEvoked potentialsHuman infantLateral interactions
Type
Research Articles
Information
Visual Neuroscience , Volume 8 , Issue 1 , January 1992 , pp. 3 - 8
Copyright
Copyright © Cambridge University Press 1992

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