Hostname: page-component-586b7cd67f-r5fsc Total loading time: 0 Render date: 2024-11-27T21:01:23.339Z Has data issue: false hasContentIssue false
  • English
  • Français

Background illumination reduces horizontal cell receptive-field size in both normal and 6-hydroxydopamine-lesioned goldfish retinas

Published online by Cambridge University Press:  02 June 2009

William H. Baldridge  and
Alexander K. Ball
William H. Baldridge
Affiliation:
Division of Anatomy and Experimental Morphology, Department of Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada
Alexander K. Ball
Affiliation:
Division of Anatomy and Experimental Morphology, Department of Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada
Get access Rights & Permissions [Opens in a new window]

Abstract

The effect of background illumination on horizontal cell receptive-field size and dye coupling was investigated in isolated superfused goldfish retinas. Background illumination reduced both horizontal cell receptive-field size and dye coupling. The effect of light on horizontal cell receptive-field size was mimicked by treating the retina with 20 μM dopamine. To test the hypothesis that the effects of light were due to endogenous dopamine release, the effect of light was studied in goldfish retinas in which dopaminergic interplexiform cells were lesioned using 6-hydroxydopamine treatment. In lesioned retinas, background illumination reduced both horizontal cell receptive-field size and dye coupling. Furthermore, the effect of background illumination on unlesioned animals could not be blocked by prior treatment with the D1 dopamine receptor antagonist SCH-23390. These results suggest that, in goldfish retina, dopamine release is not the only mechanism by which horizontal cell receptive-field size could be reduced by light.

Keywords

Horizontal cellsGoldfishGap junctionsDopamine6-hydroxydopamine
Type
Research Articles
Information
Visual Neuroscience , Volume 7 , Issue 5 , November 1991 , pp. 441 - 450
Copyright
Copyright © Cambridge University Press 1991

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Baldridge, W.H., Ball, A.K. & Miller, R.G. (1987). Dopaminergic regulation of horizontal cell gap-junction particle density in goldfish retina. Journal of Comparative Neurology 265, 428–437.CrossRefGoogle ScholarPubMed
Baldridge, W.H., Ball, A.K. & Miller, R.G. (1989). Regulation of horizontal cell gap-junction particle density in 6-OHDA lesioned goldfish retinas. Journal of Comparative Neurology 287, 238–246.CrossRefGoogle Scholar
Dearry, A. & Burnside, B. (1988). Stimulation of distinct D2 dopaminergic and alpha2-adrenergic receptors induces light-adaptive pigment dispersion in teleost retinal pigment epithelium. Journal of Neurochemistry 51, 1516–1523.CrossRefGoogle Scholar
Devries, S.H. & Schwartz, E.A. (1989). Modulation of an electrical synapse between solitary pairs of catfish horizontal cells by dopamine and second messengers. Journal of Physiology 414, 351–375.CrossRefGoogle ScholarPubMed
Dong, C.-J. & McReynolds, J.S. (1990). Light stimulates dopamine release and uncouples horizontal cells via the ON pathway in mudpuppy retina. Investigative Opthalmology and Visual Science 31, 334.Google Scholar
Dowling, J.E. & Ehinger, B. (1978). Synaptic organization of the dopaminergic neurons in the rabbit retina. Journal of Comparative Neurology 180, 203–220.CrossRefGoogle ScholarPubMed
Kamermans, M., Van Dijk, B.W. & Spekreijse, H. (1990). An evaluation of dopamine and light-induced changes in carp horizontal cells. Investigative Opthalmology and Visual Science 31, 177.Google Scholar
Knapp, A.G. & Dowling, J.E. (1987). Dopamine enhances excitatory amino acid-gated conductances in cultured retinal horizontal cells. Nature 325, 437–439.CrossRefGoogle ScholarPubMed
Lasater, E.M. & Dowling, J.E. (1985). Electrical coupling between pairs of isolated fish horizontal cells is modulated by dopamine and cAMP gap junctions. In Gap Junctions, ed. Bennet, M.V.L. & Spray, D.C., pp. 393–404. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory.Google Scholar
Mangel, S.C. & Dowling, J.E. (1985). Responsiveness and receptivefield size of carp horizontal cells are reduced by prolonged darkness and dopamine. Science 229, 1107–1109.CrossRefGoogle Scholar
Marc, R.E., Stell, W.K., Bok, D. & Lam, D.M.K. (1978). GABAergic pathways in the goldfish retina. Journal of Comparative Neurology 182, 221–245.CrossRefGoogle ScholarPubMed
McMahon, D.G., Knapp, A.G. & Dowling, J.E. (1988). Dopamine affects the open probability of gap junctions in white perch horizontal cells. Society for Neuroscience Abstracts 14, 161.Google Scholar
Naka, K.-I. & Rushton, W.A.H. (1968). S-potential and dark adaptation in fish. Journal of Physiology 194, 259–269.CrossRefGoogle ScholarPubMed
Normann, R.A. & Perlman, I. (1990). Background and bleaching adaptation in luminosity-type horizontal cells in the isolated turtle retina. Journal of Physiology 421, 321–341.CrossRefGoogle ScholarPubMed
Piccolino, M. & Demontis, G. (1988). Dopaminergic system and modulation of electrical transmission between horizontal cells in the turtle retina. In Dopaminergic Mechanisms in Vision, ed. Bodis-Wollner, I. & Piccolino, M., pp. 137–162. New York: Alan R. Liss.Google Scholar
Shigematsu, Y. & Yamada, M. (1988). Effects of dopamine on spatial properties of horizontal cell responses in the carp retina. Neuroscience Research (Suppl.) 8, S69–S80.Google ScholarPubMed
Stell, W.K. (1972). The structure and morphologic relations of rods and cones in the retina of the spiny dogfish, Squalus. Comparative Biochemistry and Physiology 42A, 141–151.Google Scholar
Stell, W.K. & Lightfoot, D.O. (1975). Color-specific interconnections of cones and horizontal cells in the retina of the goldfish. Journal of Comparative Neurology 159, 473–502.CrossRefGoogle ScholarPubMed
Teranishi, T., Negishi, K. & Kato, S. (1984). Regulatory effect of dopamine on spatial properties of horizontal cells in carp retina. Journal of Neuroscience 4, 1271–1280.CrossRefGoogle ScholarPubMed
Tornqvist, K., Yang, X.-L. & Dowling, J.E. (1988). Modulation of cone horizontal cell activity in the teleost fish retina, III: Effects of prolonged darkness and dopamine on electrical coupling between horizontal cells. Journal of Neuroscience 8, 2279–2288.CrossRefGoogle ScholarPubMed
Toyoda, J.-I. & Tonasaki, K. (1978). Effect of polarization of horizontal cells on the ON-center bipolar cell of the carp retina. Nature 276, 399–400.CrossRefGoogle Scholar
Umino, O., Lee, Y. & Dowling, J.E. (1991). Effects of light stimuli on the release of dopamine from interplexiform cells in the white perch retina. Visual Neuroscience 7, 451–458.CrossRefGoogle ScholarPubMed
Vaughan, D.K. & Lasater, E.M. (1990). Evidence for renewal of electrical synapses in teleost horizontal cells. Investigative Opthalmology and Visual Science 31, 285.Google Scholar
Weiler, R., Kohler, K., Kirsch, M. & Wagner, H.J. (1988). Glutamate and dopamine modulate synaptic plasticity in horizontal cell dendrites of fish retina. Neuroscience Letters 87, 205–209.CrossRefGoogle ScholarPubMed
Weiler, R., Kolbinger, W. & Kohler, K. (1989). Reduced light responsiveness of the cone pathway during prolonged darkness does not result from an increase of dopaminergic activity in the fish retina. Neuroscience Letters 99, 214–218.CrossRefGoogle Scholar
Witkovsky, P., Burkhardt, D.A. & Nagy, A.R. (1979). Synaptic connections linking cones and horizontal cells in the retina of the pikeperch (Stizostedion vitreum). Journal of Comparative Neurology 186, 541–560.CrossRefGoogle ScholarPubMed
Witkovsky, P., Stone, S. & Besharse, J. (1988). The effects of dopamine and related ligands on photoreceptor to horizontal cell transfer in the Xenopus retina. Biomedical Research 9, 93–107.Google Scholar
Yang, X.-L., Tornqvist, K. & Dowling, J.E. (1988). Modulation of cone horizontal cell activity in the teleost fish retina, II: Role of interplexiform cells and dopamine in regulating light responsiveness. Journal of Neuroscience 8, 2269–2278.CrossRefGoogle ScholarPubMed
Yazulla, S. & Kleinschmidt, J. (1982). Dopamine blocks carrier-mediated release of GABA from retinal horizontal cells. Brain Research 233, 211–215.CrossRefGoogle ScholarPubMed
Zigmond, M.J., Abercrombie, E.D., Berger, T.W., Grace, A.A. & Stricker, E.M. (1990). Compensation after lesions of central dopaminergic neurons: some clinical and basic implications. Trends in Neuroscience 13, 290–296.CrossRefGoogle ScholarPubMed