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Treatment Options for the Twin–Twin Transfusion Syndrome: A Review

Published online by Cambridge University Press:  21 February 2012

Mariola Ropacka
Affiliation:
Department of Perinatology and Gynecology, University School of Medical Sciences, Poznan, Poland.
Wieslaw Markwitz
Affiliation:
Department of Perinatology and Gynecology, University School of Medical Sciences, Poznan, Poland.
lsaac Blickstein*
Affiliation:
Department of Obstetrics and Gynecology, Kaplan Medical Center (affiliated with the Hadassah-Hebrew University, School of Medicine, Jerusalem), Rehovot, Israel. [email protected]
*
*Address for correspondence: Isaac Blickstein, MD, Department of Obstetrics and Gynecology Kaplan Medical Center, 76100 Rehovot, Israel.

Abstract

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This article reviews the treatment options of the twin–twin transfusion syndrome (TTTS). No single therapy is associated with a uniformly improved outcome for the involved twins and success is primarily related to gestational age and severity at diagnosis. Treatment options for severe cases include digitalization, ligation of the umbilical cord, serial amniocenteses, septostomy, laser occlusion of placental vessels, and selective feticide. These modalities are associated with significant risks of complications, and variable results of fetal morbidity and mortality. Therefore, they should be considered when risks of withholding treatment clearly outweigh those associated with intervention.

Type
Articles
Copyright
Copyright © Cambridge University Press 2002