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Interaction of marital status and genetic risk for symptoms of depression

Published online by Cambridge University Press:  21 February 2012

Andrew C Heath ,
Lindon J Eaves  and
Nicholas G Martin
Andrew C Heath
Affiliation:
Department of Psychiatry, Washington University, St Louis.
Lindon J Eaves
Affiliation:
Virginia Institute of Psychiatric and Behavioral Genetics, Richmond, USA.
Nicholas G Martin*
Affiliation:
Queensland Institute of Medical Research, Brisbane, Australia. [email protected]
*
*Correspondence: Dr NG Martin, Queensland Institute of Medical Research, Post Office, Royal Brisbane Hospital, Brisbane 4029, Australia. Fax: + 61 7 3362 0101

Abstract

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Depression scores (DSSI) were available for 1232 MZ and 751 DZ female twin pairs who completed a mailed questionnaire. Pairs were divided into those concordant for being in a marriage-like state, concordant for having no partners, and those discordant. The pattern of twin correlations differed according to marital status. Our results suggest that having a marriage-like relationship acts as a protective factor in reducing the impact of inherited liability to symptoms of depression in the general population.

Keywords

twinsdepressionmarital statusgenotype environment interaction
Type
Articles
Information
Twin Research and Human Genetics , Volume 1 , Issue 3 , 01 June 1998 , pp. 119 - 122
Copyright
Copyright © Cambridge University Press 1998